XSB0046 : PREDICTED: similar to von Willebrand factor [Rattus norvegicus]
[ CaMP Format ]
This entry is computationally expanded from SB0030
* Basic Information
| Organism | Rattus norvegicus (Norway rat) |
| Protein Names | similar to von Willebrand factor |
| Gene Names | Vwf; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 8 mRNAs, 32 ESTs, 5 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 2812 aa
Average Mass: 308.995 kDa
Monoisotopic Mass: 308.790 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| VWD 1. | 35 | 179 | 140.7 | 4.5e-39 |
| C8 1. | 218 | 292 | 87.9 | 3.6e-23 |
| TIL 1. | 295 | 348 | 41.8 | 2.8e-09 |
| VWD 2. | 388 | 541 | 177.1 | 4.9e-50 |
| C8 2. | 577 | 649 | 122.5 | 1.4e-33 |
| TIL 2. | 652 | 707 | 39.2 | 1.6e-08 |
| TIL 3. | 776 | 827 | 26.8 | 9.1e-05 |
| VWD 3. | 867 | 1013 | 145.0 | 2.4e-40 |
| C8 3. | 1053 | 1127 | 115.2 | 2.2e-31 |
| TIL 4. | 1142 | 1196 | 34.2 | 5.3e-07 |
| Granulin 1. | 1205 | 1236 | -18.7 | 3.8 |
| VWA 1. | 1277 | 1453 | 108.0 | 3.2e-29 |
| VWA 2. | 1498 | 1664 | 169.8 | 7.7e-48 |
| VWA 3. | 1691 | 1858 | 131.6 | 2.5e-36 |
| fn1 1. | 1879 | 1919 | -8.7 | 8.4 |
| --- cleavage 1913 (inside fn1 1879..1919) --- |
| VWD 4. | 1950 | 2102 | 126.3 | 1e-34 |
| C8 4. | 2132 | 2200 | 92.4 | 1.5e-24 |
| TIL 5. | 2203 | 2254 | 5.9 | 0.01 |
| VWC 1. | 2257 | 2325 | 73.4 | 8.3e-19 |
| Laminin_EGF 1. | 2340 | 2375 | -25.6 | 9.2 |
| VWC 2. | 2431 | 2494 | 81.1 | 3.9e-21 |
| Antistasin 1. | 2548 | 2569 | 7.4 | 0.29 |
| VWC 3. | 2581 | 2643 | 60.1 | 8.5e-15 |
| Cys_knot 1. | 2715 | 2810 | -29.6 | 0.35 |
3. Sequence Information
Fasta Sequence: XSB0046.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] CLANGQTLLQ1913-SHRVNCDHGP
Gln1913 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Cys1904 | Leu1905 | Ala1906 | Asn1907 | Gly1908 | Gln1909 | Thr1910 | Leu1911 | Leu1912 | Gln1913 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser1914 | His1915 | Arg1916 | Val1917 | Asn1918 | Cys1919 | Asp1920 | His1921 | Gly1922 | Pro1923 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
GNEKRPGDVWTLPDQCHTVTCLANGQTLLQSHRVNCDHGPRPSCSNSQSPVRVEETCGCR
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Rattus norvegicus |
137.00 |
4 |
PREDICTED: similar to von Willebrand factor |
| 2 |
Mus musculus |
136.00 |
15 |
VWF |
| 3 |
Contains: von Willebrand antigen 2 (von Willebrand antigen II) |
136.00 |
2 |
VWF_MOUSE von Willebrand factor precursor (vWF) |
| 4 |
N/A |
122.00 |
8 |
V |
| 5 |
Canis familiaris |
122.00 |
3 |
von Willebrand factor |
| 6 |
Canis lupus familiaris |
122.00 |
1 |
von Willebrand factor |
| 7 |
Homo sapiens |
120.00 |
17 |
von Willebrand factor, isoform CRA_a |
| 8 |
Pan troglodytes |
120.00 |
2 |
PREDICTED: von Willebrand factor isoform 2 |
| 9 |
Bos taurus |
112.00 |
4 |
PREDICTED: similar to von Willebrand factor precur |
| 10 |
Sus scrofa |
110.00 |
1 |
VWF_PIG von Willebrand factor precursor (vWF) gb |
| 11 |
Gallus gallus |
92.40 |
2 |
PREDICTED: similar to von Willebrand factor precur |
| 12 |
Tetraodon nigroviridis |
78.60 |
1 |
unnamed protein product |
| 13 |
Macaca mulatta |
41.60 |
1 |
PREDICTED: mucin 2 |
| 14 |
Oryza sativa (japonica cultivar-group) |
34.30 |
1 |
OJ1005_B10.1 |
Top-ranked sequences
| organism | matching |
|---|
| Rattus norvegicus |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|
| Mus musculus |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||||||||||||||||||||||||||||||#||||||||||||||+|||||||||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCANSQSPVRVEETCGCR 1943
|
| Contains: von Willebrand antigen 2 (von Willebrand antigen II) |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||||||||||||||||||||||||||||||#||||||||||||||+|||||||||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCANSQSPVRVEETCGCR 1943
|
| N/A |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|||||||||||||||||||||| +|||||+#||||||| |||||| | | |+|||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCLPDGQTLLK#SHRVNCDRGPRPSCPNGQPPLRVEETCGCR 1943
|
| Canis familiaris |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|||||||||||||||||||||| +|||||+#||||||| |||||| | | |+|||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCLPDGQTLLK#SHRVNCDRGPRPSCPNGQPPLRVEETCGCR 1943
|
| Canis lupus familiaris |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|||||||||||||||||||||| +|||||+#||||||| |||||| | | |+|||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCLPDGQTLLK#SHRVNCDRGPRPSCPNGQPPLRVEETCGCR 1943
|
| Homo sapiens |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||||||||||||||||||||| +|||||+#||||||| | |||| ||||||+||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCQPDGQTLLK#SHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
|
| Pan troglodytes |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||||||||||||||||||||| +|||||+#||||||| | |||| ||||||+||||||||
Sbjct 1884 GNEKRPGDVWTLPDQCHTVTCQPDGQTLLK#SHRVNCDRGLRPSCPNSQSPVKVEETCGCR 1943
|
| Bos taurus |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|||+|||||||| ||||||||| +|||||+#||||||| ||+||| + |+|+|+|| ||||
Sbjct 1899 GNERRPGDVWTLLDQCHTVTCLPDGQTLLK#SHRVNCDQGPQPSCPDGQTPLRMEEACGCR 1958
|
| Sus scrofa |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|+|++||||||||||||||||| +|||||+#||||||| | +||| ++| |+|||| ||||
Sbjct 1553 GSERKPGDVWTLPDQCHTVTCLPDGQTLLK#SHRVNCDQGLQPSCPSNQPPIRVEEACGCR 1612
|
| Gallus gallus |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
||+|+||| |||||||||||| |+|+#||++||+ |+| | ++ |+||||||||
Sbjct 1865 GNKKKPGDKWTLPDQCHTVTCFPGDYTVLE#SHQINCERMPKPVCHSNLPAVKVEETCGCR 1924
|
| Tetraodon nigroviridis |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGCR 1943
|||++||| | | | ||+| | +| +|#+ +|+|| |||||+ ||||++|| ||
Sbjct 2001 GNERKPGDTWLLEDGCHSVLCHPSGAVTVQ#TRKVSCDTQELPSCSNNMPPVRVQDTCNCR 2060
|
| Macaca mulatta |
Query 1887 KRPGDVWTLPDQCHTVTCLANGQTLLQ#SHRVNCDHGPRPSCSNSQSPVRVEETCGC 1942
++ + | | | | || | ++# || |+ | |+||| +|||| + ||
Sbjct 233 RQENETWWLCD-CFMATCKYNNT--VE#IVRVECEPPPMPTCSNGLTPVRVSDPDGC 285
|
| Oryza sativa (japonica cultivar-group) |
Query 1884 GNEKRPGDVWTLPDQCHTVTCLANGQTLLQ--------#SHRVNCDHGPRPSCSNSQSPVR 1935
| |||| +|||+|| | | | | | | #| || || | + | |
Sbjct 62 GREKRPEEVWTVPDDCST-DC-RNLSTFFQLPLHLSRS#SPRV-AGQGPWP-----RVPHR 113
Query 1936 VE-ETCGCR 1943
| |||| +
Sbjct 114 AEHETCGLK 122
|
