XSB0266 : insulin-like growth factor binding protein 4 [Bos taurus]
[ CaMP Format ]
This entry is computationally expanded from SB0070
* Basic Information
| Organism | Bos taurus (cattle) |
| Protein Names | Insulin-like growth factor-binding protein 4; IGF-binding protein 4; IGFBP-4; IBP-4; insulin-like growth factor binding protein 4 |
| Gene Names | IGFBP4; insulin-like growth factor binding protein 4 |
| Gene Locus | 19; chromosome 19 |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_776982 | NM_174557 | 282262 | Q05716 | N/A | N/A | N/A | bta:282262 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 258 aa
Average Mass: 27.890 kDa
Monoisotopic Mass: 27.872 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 23 --- | ||||
| IGFBP 1. | 27 | 85 | 101.6 | 2.6e-27 |
| --- cleavage 143 --- | ||||
| --- cleavage 107 --- | ||||
| Thyroglobulin_1 1. | 174 | 249 | 144.0 | 4.7e-40 |
3. Sequence Information
Fasta Sequence: XSB0266.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] AGPGPSLGDE23-AIHCPPCSEE
Glu23 
Ala
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ala14 | Gly15 | Pro16 | Gly17 | Pro18 | Ser19 | Leu20 | Gly21 | Asp22 | Glu23 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala24 | Ile25 | His26 | Cys27 | Pro28 | Pro29 | Cys30 | Ser31 | Glu32 | Glu33 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MLSLCLMAALLLAAGPGPSLGDEAIHCPPCSEEKLARCRPPVGCEELVREPGC |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Homo sapiens | 79.30 | 16 | insulin-like growth factor binding protein 4 precu |
| 2 | Mus musculus | 79.30 | 14 | unnamed protein product |
| 3 | synthetic construct | 79.30 | 8 | insulin-like growth factor binding protein 4 |
| 4 | Rattus norvegicus | 79.30 | 7 | insulin-like growth factor binding protein 4 |
| 5 | Sus scrofa | 79.30 | 6 | IBP4 |
| 6 | Bos taurus | 79.30 | 5 | insulin-like growth factor binding protein 4 |
| 7 | Pan troglodytes | 79.30 | 2 | PREDICTED: similar to Insulin-like growth factor-b |
| 8 | N/A | 77.00 | 14 | B |
| 9 | Ovis aries | 77.00 | 2 | IBP4_SHEEP Insulin-like growth factor-binding prot |
| 10 | Equus caballus | 77.00 | 1 | insulin-like growth factor binding protein-4 |
| 11 | Canis familiaris | 76.30 | 4 | PREDICTED: similar to Insulin-like growth factor b |
| 12 | Monodelphis domestica | 76.30 | 4 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 13 | Gallus gallus | 60.50 | 3 | insulin-like growth factor binding protein 4 |
| 14 | Tetraodon nigroviridis | 60.10 | 5 | unnamed protein product |
| 15 | human, TE85 osteosarcoma cells, Peptide Partial, 21 aa | 48.10 | 1 | insulin-like growth factor binding protein 4, IGFB |
| 16 | Danio rerio | 46.60 | 11 | insulin-like growth factor binding protein 1 |
| 17 | Xenopus laevis | 45.40 | 4 | insulin-like growth factor binding protein 1 |
| 18 | Macaca mulatta | 42.70 | 8 | PREDICTED: similar to insulin-like growth factor b |
| 19 | Xenopus tropicalis | 42.00 | 4 | Unknown (protein for MGC:144994) |
| 20 | Salmo salar | 39.70 | 5 | IGF binding protein 1 |
| 21 | Oncorhynchus mykiss | 39.70 | 4 | insulin-like growth factor binding protein 1 |
| 22 | Spermophilus tridecemlineatus | 39.70 | 1 | IBP1_SPETR Insulin-like growth factor-binding prot |
| 23 | Oncorhynchus tshawytscha | 39.70 | 1 | insulin-like growth factor binding protein-1 |
| 24 | Papio anubis | 37.70 | 1 | insulin-like growth factor binding protein-1 |
| 25 | Sparus aurata | 37.40 | 1 | AF377998_1 insulin-like growth factor binding prot |
| 26 | chickens, eye, Peptide Partial, 51 aa | 36.60 | 1 | insulin-like growth factor binding protein-5, IGFB |
Top-ranked sequences
| organism | matching |
|---|---|
| Homo sapiens | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Mus musculus | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| synthetic construct | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Rattus norvegicus | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Sus scrofa | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Bos taurus | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Pan troglodytes | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||||||||||||||||| Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| N/A | Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 ||#|||||||||||||||||||||||||||||| Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Ovis aries | Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 ||#|||||||||||||||||||||||||||||| Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Equus caballus | Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 ||#|||||||||||||||||||||||||||||| Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |
| Canis familiaris | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#||||| |||||||||||||||||||||||| Sbjct 214 GDE#AIHCPSCSEEKLARCRPPVGCEELVREPGC 246 |
| Monodelphis domestica | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |||#|||||||||||||||+|| ||||||||||| Sbjct 21 GDE#AIHCPPCSEEKLARCQPPTGCEELVREPGC 53 |
| Gallus gallus | Query 21 GDE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |+|#| |||||||+||||+ | || | |||||| Sbjct 26 GEE#ATQCPPCSEERLARCKAPQGCTESVREPGC 58 |
| Tetraodon nigroviridis | Query 22 DE#AIHCPPCSEEKLARCRPPVGCEELVREPGC 53 |+#|| || ||||+||||| | |||| |||||| Sbjct 31 DQ#AIRCPVCSEERLARCRLPEGCEETVREPGC 62 |
| human, TE85 osteosarcoma cells, Peptide Partial, 21 aa | Query 22 DE#AIHCPPCSEEKLARCRPPV 42 ||#|||||| |||||||||||| Sbjct 1 DE#AIHCPPXSEEKLARCRPPV 21 |
| Danio rerio | Query 21 GDE#AIHCPPCSEEKLARCRPPV--GCEELVREPGC 53 | |# | | ||| |+|| | | | ||||++||||| Sbjct 30 GQE#PIRCAPCSPERLAEC-PAVDAGCEEVLREPGC 63 |
| Xenopus laevis | Query 23 E#AIHCPPCSEEKLARCRP-PVGCEELVREPGC 53 |#++|| |+||+|| | | | | || ||||| Sbjct 26 E#SLHCAQCTEERLALCPPVPSDCPELAREPGC 57 |
| Macaca mulatta | Query 25 IHCPPCSEEKLARCRP-PVGCEELVREPGC 53 +|| || |+ |+ | | |+|| |||+|||| Sbjct 25 VHCEPCDEKALSMCPPSPLGC-ELVKEPGC 53 |
| Xenopus tropicalis | Query 25 IHCPPCSEEKLARCRP-PVGCEELVREPGC 53 +|| || ++ ++ | | |||| |||+|||| Sbjct 25 VHCEPCDDKAMSMCPPTPVGC-ELVKEPGC 53 |
| Salmo salar | Query 21 GDE#AIHCPPCSEEKLARCRPPVG--CEELVREPGC 53 | |# | | ||++||| | | + |++++||||| Sbjct 30 GPE#PIRCAPCTQEKLDEC-PAISPDCKQVLREPGC 63 |
| Oncorhynchus mykiss | Query 21 GDE#AIHCPPCSEEKLARCRPPVG--CEELVREPGC 53 | |# | | ||++||| | | + |++++||||| Sbjct 30 GPE#PIRCAPCTQEKLDEC-PAISPDCKQVLREPGC 63 |
| Spermophilus tridecemlineatus | Query 26 HCPPCSEEKLARCRP-PVGCEELVREPGC 53 || ||| |||| | | | | || | || Sbjct 31 HCAPCSAEKLALCPPVPSSCPELSRPAGC 59 |
| Oncorhynchus tshawytscha | Query 21 GDE#AIHCPPCSEEKLARCRPPVG--CEELVREPGC 53 | |# | | ||++||| | | + |++++||||| Sbjct 30 GPE#PIRCAPCTQEKLDEC-PAISPDCKQVLREPGC 63 |
| Papio anubis | Query 27 CPPCSEEKLARCRP-PVGCEELVREPGC 53 | ||| |||| | | | | |+ | || Sbjct 30 CAPCSAEKLALCPPVPASCSEVTRSAGC 57 |
| Sparus aurata | Query 21 GDE#AIHCPPCSEEKLARC-RPPVGCEELVREPGC 53 || #| || |+ |+|| | + | |+||| || Sbjct 22 GDL#AFRCPSCTAERLAACPKVTAMCPEIVRELGC 55 |
| chickens, eye, Peptide Partial, 51 aa | Query 25 IHCPPCSEEKLARCRPP-VGCEELVREPGC 53 + | || + |+ | || +||| ||+|||| Sbjct 5 VQCEPCDGKALSLCPPPPLGCE-LVKEPGC 33 |
[Site 2] HDRKCLQKHL143-AKIRDRSTSG
Leu143 Ala
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| His134 | Asp135 | Arg136 | Lys137 | Cys138 | Leu139 | Gln140 | Lys141 | His142 | Leu143 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala144 | Lys145 | Ile146 | Arg147 | Asp148 | Arg149 | Ser150 | Thr151 | Ser152 | Gly153 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QPSDKDEGDHPNNSFSPCSAHDRKCLQKHLAKIRDRSTSGGKMKVIGAPREEARPVPQGS |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 129.00 | 2 | insulin-like growth factor binding protein 4 |
| 2 | Ovis aries | 128.00 | 1 | IBP4_SHEEP Insulin-like growth factor-binding prot |
| 3 | Canis familiaris | 125.00 | 1 | PREDICTED: similar to Insulin-like growth factor b |
| 4 | Equus caballus | 125.00 | 1 | insulin-like growth factor binding protein-4 |
| 5 | Homo sapiens | 123.00 | 2 | insulin-like growth factor binding protein 4 precu |
| 6 | N/A | 123.00 | 2 | - |
| 7 | synthetic construct | 123.00 | 2 | insulin-like growth factor binding protein 4 |
| 8 | Sus scrofa | 123.00 | 1 | IBP4 |
| 9 | Pan troglodytes | 123.00 | 1 | PREDICTED: similar to Insulin-like growth factor-b |
| 10 | Mus musculus | 99.80 | 3 | insulin-like growth factor binding protein-4 |
| 11 | Rattus norvegicus | 99.80 | 2 | insulin-like growth factor binding protein 4 |
| 12 | Monodelphis domestica | 85.10 | 1 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 13 | Gallus gallus | 76.60 | 1 | insulin-like growth factor binding protein 4 |
| 14 | Bubalus bubalis | 76.30 | 1 | insulin-like growth factor binding protein-4 |
| 15 | Tetraodon nigroviridis | 37.00 | 1 | unnamed protein product |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |
| Ovis aries | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 ||||||||||||||||||||||||||||||#|||||||||||||||||||||| ||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEVRPVPQGS 152 |
| Canis familiaris | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #||||||||||||||||| |||||||||||| Sbjct 307 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVIGVPREEARPVPQGS 366 |
| Equus caballus | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #|||||||||||||||+| |||||||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 152 |
| Homo sapiens | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
| N/A | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
| synthetic construct | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
| Sus scrofa | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 ||||||||||||||||||| ||+||||||#|||||||||||||||||||||||||||||| Sbjct 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 |
| Pan troglodytes | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
| Mus musculus | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 | ||||| +||||||+|||||| +|||||+#||||||| |||++| |||| ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKIRDRS----KMKIVGTPREEPRPVPQGS 169 |
| Rattus norvegicus | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 | ||||| +||||||+|||||| +|||||+#||+|||| ||||+| |||| ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKVRDRS----KMKVVGTPREEPRPVPQGS 169 |
| Monodelphis domestica | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIG--APREEARPVPQ 171 | ++|+| +||||||||||+|||||+||| #|||| |++ |||| || | ||+ ||+ | Sbjct 114 QTTEKEESEHPNNSFSPCSSHDRKCMQKHS#AKIRVVSSNSGKMKSIGSSAHREDTRPMAQ 173 Query 172 GS 173 || Query 172 GS 173 |
| Gallus gallus | Query 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAP--REEARPVPQ 171 || +|+| +|||||||||| |||||||| #|| | +| ||+ |+| |||+||+ | Sbjct 119 QPPEKEEIEHPNNSFSPCSIHDRKCLQKQQ#AK---RINNGNKMRSSGSPHHREESRPIAQ 175 Query 172 GS 173 || Query 172 GS 173 |
| Bubalus bubalis | Query 138 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 ||||||#|||||||||||||||||||||||||||||| Query 138 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |
| Tetraodon nigroviridis | Query 122 DHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTS 152 +||||| || |++|+|| |#|+ +||+ Sbjct 130 EHPNNSNIRCSQQDKRCIQKTL#ARHLSKSTN 160 |
[Site 3] GVCMELAEIE107-AIQESLQPSD
Glu107 Ala
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gly98 | Val99 | Cys100 | Met101 | Glu102 | Leu103 | Ala104 | Glu105 | Ile106 | Glu107 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala108 | Ile109 | Gln110 | Glu111 | Ser112 | Leu113 | Gln114 | Pro115 | Ser116 | Asp117 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| LRCYPPRGVEKPLHTLVHGQGVCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSAHDRK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Bos taurus | 132.00 | 5 | insulin-like growth factor binding protein 4 |
| 2 | Ovis aries | 130.00 | 3 | IBP4_SHEEP Insulin-like growth factor-binding prot |
| 3 | Homo sapiens | 129.00 | 10 | insulin-like growth factor binding protein 4 precu |
| 4 | N/A | 129.00 | 10 | - |
| 5 | synthetic construct | 129.00 | 4 | insulin-like growth factor binding protein 4 |
| 6 | Canis familiaris | 128.00 | 4 | PREDICTED: similar to Insulin-like growth factor b |
| 7 | Pan troglodytes | 128.00 | 2 | PREDICTED: similar to Insulin-like growth factor-b |
| 8 | Equus caballus | 128.00 | 2 | insulin-like growth factor binding protein-4 |
| 9 | Sus scrofa | 123.00 | 6 | IBP4 |
| 10 | Monodelphis domestica | 115.00 | 4 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 11 | Mus musculus | 112.00 | 9 | insulin-like growth factor binding protein 4 |
| 12 | Rattus norvegicus | 112.00 | 5 | insulin-like growth factor binding protein 4 |
| 13 | Gallus gallus | 110.00 | 3 | insulin-like growth factor binding protein 4 |
| 14 | Tetraodon nigroviridis | 68.60 | 5 | unnamed protein product |
| 15 | Xenopus tropicalis | 45.10 | 3 | Unknown (protein for MGC:144994) |
| 16 | Xenopus laevis | 43.90 | 4 | insulin-like growth factor binding protein 5 |
| 17 | Danio rerio | 41.20 | 9 | insulin-like growth factor binding protein 5 |
| 18 | Salmo salar | 40.80 | 1 | IGF binding protein 5 |
| 19 | Oncorhynchus mykiss | 40.80 | 1 | insulin-like growth factor binding protein 5 |
| 20 | Macaca mulatta | 40.00 | 5 | PREDICTED: similar to insulin-like growth factor b |
| 21 | Bubalus bubalis | 39.30 | 1 | insulin-like growth factor binding protein-5 |
| 22 | Coturnix japonica | 38.90 | 1 | AF293839_1 insulin-like growth factor binding prot |
| 23 | Oncorhynchus tshawytscha | 32.30 | 1 | insulin-like growth factor binding protein-1 |
Top-ranked sequences
| organism | matching |
|---|---|
| Bos taurus | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 |
| Ovis aries | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 |||+||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 57 LRCHPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 116 |
| Homo sapiens | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||||||||||||#|||||||||||||||||||||||||||||+ Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
| N/A | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||||||||||||#|||||||||||||||||||||||||||||+ Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
| synthetic construct | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||||||||||||#|||||||||||||||||||||||||||||+ Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
| Canis familiaris | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||||||||+|||#|||||||||||||||||||||||||||||+ Sbjct 271 LRCYPPRGVEKPLHTLMHGQGVCMELSEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 330 |
| Pan troglodytes | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+||||+||||||||#|||||||||||||||||||||||||||||+ Sbjct 78 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
| Equus caballus | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||||||||||||#||||+||||||||||||||||||||||||+ Sbjct 57 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQENLQPSDKDEGDHPNNSFSPCSAHDRR 116 |
| Sus scrofa | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+||||+||||||||#||||||||||||||||||||||||| ||+ Sbjct 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |
| Monodelphis domestica | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||||||||+|||| |||||+||#||||||| ++|+| +||||||||||+|||| Sbjct 78 LRCYPPRGVEKPLHTLMHGQGECMELADIE#AIQESLQTTEKEESEHPNNSFSPCSSHDRK 137 |
| Mus musculus | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 +|||||||||||| ||+|||||| ||+|||#||||||| ||||| +||||||+|||||| + Sbjct 78 MRCYPPRGVEKPLRTLMHGQGVCTELSEIE#AIQESLQTSDKDESEHPNNSFNPCSAHDHR 137 |
| Rattus norvegicus | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 +|||||||||||| ||+|||||| ||+|||#||||||| ||||| +||||||+|||||| + Sbjct 78 MRCYPPRGVEKPLRTLMHGQGVCTELSEIE#AIQESLQTSDKDESEHPNNSFNPCSAHDHR 137 |
| Gallus gallus | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||| +|||||+|||||| +||++|#|||||||| +|+| +|||||||||| |||| Sbjct 83 LRCYPPRGVPRPLHTLMHGQGVCTDLADVE#AIQESLQPPEKEEIEHPNNSFSPCSIHDRK 142 |
| Tetraodon nigroviridis | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 ||||||||||+|||+|+|||||| + |+|# + |+ +||||| || |++ Sbjct 87 LRCYPPRGVERPLHSLMHGQGVCTDEREVE#E-NSATDRQDEIIPEHPNNSNIRCSQQDKR 145 |
| Xenopus tropicalis | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMEL------AEIE#AIQE 111 ||| | +| ||||| |+||+|||+ | ++|+#+|+| Sbjct 78 LRCLPEQGEEKPLHALLHGRGVCLNLKNHRDQSKID#SIEE 117 |
| Xenopus laevis | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMEL 103 ||| | +| ||||| |+||+|||+ | Sbjct 79 LRCLPEQGEEKPLHALLHGRGVCLNL 104 |
| Danio rerio | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDR 136 ||| | | ||||| |+||+||| +# + | |++ +| +++ | + |+ Sbjct 74 LRCLPRNGEEKPLHALLHGRGVC---TNEK#GYKPPHPPIDRESIEH-DDTVKPDTTEDQ 128 |
| Salmo salar | Query 78 LRCYPPRGVEKPLHTLVHGQGVC 100 ||| | | ||||| |+||+||| Sbjct 76 LRCLPRNGEEKPLHALLHGRGVC 98 |
| Oncorhynchus mykiss | Query 78 LRCYPPRGVEKPLHTLVHGQGVC 100 ||| | | ||||| |+||+||| Sbjct 76 LRCLPRNGEEKPLHALLHGRGVC 98 |
| Macaca mulatta | Query 78 LRCYPPRGVEKPLHTLVHGQGVCME----LAEIE#AIQESLQPSDKDEGDHPNNSFSP 130 ||| | + ||||| |+||+|||+ +++# ++| + + + ++|| Sbjct 78 LRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVK#IERDSREHEEPTTSEMAEETYSP 134 |
| Bubalus bubalis | Query 78 LRCYPPRGVEKPLHTLVHGQGVCM 101 ||| | + ||||| |+||+|||+ Sbjct 34 LRCLPRQDEEKPLHALLHGRGVCL 57 |
| Coturnix japonica | Query 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNS 127 +|| | +| ||||| |+|| || |+| # +++ + | + | | Sbjct 34 VRCLPRQGEEKPLHALLHGTAVC--LSEKS#YREQAKAERESREHEEPTTS 81 |
| Oncorhynchus tshawytscha | Query 78 LRCYPPRGVEKPLHTLVHGQGVCME 102 |+| | | +|||+| || +| | Sbjct 88 LKCSPRAGDPRPLHSLTRGQAICTE 112 |
* References
[PubMed ID: 16159699] Canty MJ, Boland MP, Evans AC, Crowe MA, Alterations in follicular IGFBP mRNA expression and follicular fluid IGFBP concentrations during the first follicle wave in beef heifers. Anim Reprod Sci. 2006 Jul;93(3-4):199-217. Epub 2005 Sep 12.
[PubMed ID: 1282670] ... Moser DR, Lowe WL Jr, Dake BL, Booth BA, Boes M, Clemmons DR, Bar RS, Endothelial cells express insulin-like growth factor-binding proteins 2 to 6. Mol Endocrinol. 1992 Nov;6(11):1805-14.