XSB0421 : glycine transporter type-2 a form [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0013
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | glycine transporter type-2 a form |
| Gene Names | GlyT2 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein |
Entrez Nucleotide |
Entrez Gene |
UniProt |
OMIM |
HGNC |
HPRD |
KEGG |
| BAD16782 |
N/A |
N/A |
Q761U9 |
N/A |
N/A |
N/A |
mmu: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 182 aa
Average Mass: 18.461 kDa
Monoisotopic Mass: 18.450 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| TT_ORF2a 1. | 34 | 81 | -2.3 | 6.7 |
3. Sequence Information
Fasta Sequence: XSB0421.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] NTPAVGWVNM156-SQSTVVLGTD
Met156 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Asn147 | Thr148 | Pro149 | Ala150 | Val151 | Gly152 | Trp153 | Val154 | Asn155 | Met156 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser157 | Gln158 | Ser159 | Thr160 | Val161 | Val162 | Leu163 | Gly164 | Thr165 | Asp166 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
LRGPEEDANVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIP
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Mus musculus |
115.00 |
7 |
glycine transporter type-2 a form |
| 2 |
Rattus norvegicus |
108.00 |
2 |
sodium dependent glycine type 2b transporter |
| 3 |
Macaca mulatta |
99.80 |
1 |
PREDICTED: solute carrier family 6 (neurotransmitt |
| 4 |
Homo sapiens |
98.20 |
6 |
Solute carrier family 6 (neurotransmitter transpor |
| 5 |
N/A |
98.20 |
1 |
S |
| 6 |
Pan troglodytes |
96.70 |
1 |
PREDICTED: solute carrier family 6 (neurotransmitt |
| 7 |
Bos taurus |
95.90 |
1 |
PREDICTED: similar to glycine transporter GLYT2 is |
| 8 |
Canis familiaris |
87.00 |
1 |
PREDICTED: similar to Sodium- and chloride-depende |
| 9 |
Monodelphis domestica |
78.20 |
1 |
PREDICTED: similar to glycine transporter GLYT2 |
| 10 |
Gallus gallus |
59.30 |
1 |
PREDICTED: similar to glycine transporter GLYT2 |
| 11 |
Danio rerio |
45.40 |
1 |
solute carrier family 6 (neurotransmitter transpor |
| 12 |
Tetraodon nigroviridis |
45.40 |
1 |
unnamed protein product |
Top-ranked sequences
| organism | matching |
|---|
| Mus musculus |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVATTTIP 182
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVATTTIP 182
|
| Rattus norvegicus |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVATTTIP 182
||||||| |||| |||||||||| ||||||#||||||||||||||||||||||||||
Sbjct 119 LRGPEEDENVSVAKGTLEHNNTPPVGWVNM#SQSTVVLGTDGIASVLPGSVATTTIP 174
|
| Macaca mulatta |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||||| |||||||||||| |||||||||||#|||||||||||| |||||||||
Sbjct 169 LRGPEGDANVSVGKGTLERNNTPAVGWVNM#SQSTVVLGTDGITSVLPGSVAT 220
|
| Homo sapiens |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||||| |||||||||||| |||| ||||||#|||||||||||| |||||||||
Sbjct 125 LRGPEGDANVSVGKGTLERNNTPVVGWVNM#SQSTVVLGTDGITSVLPGSVAT 176
|
| N/A |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||||| |||||||||||| |||| ||||||#|||||||||||| |||||||||
Sbjct 125 LRGPEGDANVSVGKGTLERNNTPVVGWVNM#SQSTVVLGTDGITSVLPGSVAT 176
|
| Pan troglodytes |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||||| |||||||||||| |||| |||||+#|||||||||||| |||||||||
Sbjct 125 LRGPEGDANVSVGKGTLERNNTPVVGWVNV#SQSTVVLGTDGITSVLPGSVAT 176
|
| Bos taurus |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||| | |||||||||||| |||||||||||#|||||||||||| |||||||||
Sbjct 126 LRGLEGDANVSVGKGTLERNNTPAVGWVNM#SQSTVVLGTDGITSVLPGSVAT 177
|
| Canis familiaris |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVAT 178
||||| || |||||||| |+||| |||||#||| |||||||| ||||||||+
Sbjct 232 LRGPEGDAAASVGKGTLERNSTPAGGWVNM#SQSAVVLGTDGITSVLPGSVAS 283
|
| Monodelphis domestica |
Query 127 LRGPE--EDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSVATTTIP 182
||| |+ + | |||||| |+| | ||+||#|||||||||||| ||||||| ||+ |
Sbjct 122 LRGASVGEEESGSSGKGTLERNSTQAAGWINM#SQSTVVLGTDGITSVLPGSVTTTSTP 179
|
| Gallus gallus |
Query 127 LRGPEEDANVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSV 176
|+ + ||| ++|| ||| || + || +#||||||||||| ||||| |
Sbjct 183 LQSTDGDANAALGKSTLEQNNAKST-WVTL#SQSTVVLGTDGNTSVLPGRV 231
|
| Danio rerio |
Query 135 NVSVGKGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSV 176
| | + ||||+ | +|#||+|++||||| |||||+|
Sbjct 110 NQSAVRIAAEHNNSTG-DWTSM#SQTTIILGTDGNTSVLPGTV 150
|
| Tetraodon nigroviridis |
Query 140 KGTLEHNNTPAVGWVNM#SQSTVVLGTDGIASVLPGSV 176
+ | | |||| | |#||+|++||||| || ||+|
Sbjct 54 RATAEQNNTPGT-WTAM#SQTTIILGTDGNTSVQPGTV 89
|
[Site 2] NMSQSTVVLG164-TDGIASVLPG
Gly164 Thr
|
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Asn155 | Met156 | Ser157 | Gln158 | Ser159 | Thr160 | Val161 | Val162 | Leu163 | Gly164 |
|
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Thr165 | Asp166 | Gly167 | Ile168 | Ala169 | Ser170 | Val171 | Leu172 | Pro173 | Gly174 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
NVSVGKGTLEHNNTPAVGWVNMSQSTVVLGTDGIASVLPGSVATTTIP
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Mus musculus |
99.00 |
7 |
glycine transporter type-2 a form |
| 2 |
Rattus norvegicus |
94.70 |
2 |
sodium dependent glycine type 2b transporter |
| 3 |
Macaca mulatta |
86.30 |
1 |
PREDICTED: solute carrier family 6 (neurotransmitt |
| 4 |
Bos taurus |
86.30 |
1 |
PREDICTED: similar to glycine transporter GLYT2 is |
| 5 |
Homo sapiens |
84.70 |
6 |
AF352733_1 glycine type 2 transporter variant SC6 |
| 6 |
N/A |
84.70 |
1 |
S |
| 7 |
Pan troglodytes |
83.20 |
1 |
PREDICTED: solute carrier family 6 (neurotransmitt |
| 8 |
Monodelphis domestica |
76.30 |
1 |
PREDICTED: similar to glycine transporter GLYT2 |
| 9 |
Canis familiaris |
74.30 |
1 |
PREDICTED: similar to Sodium- and chloride-depende |
| 10 |
Gallus gallus |
53.90 |
1 |
PREDICTED: similar to glycine transporter GLYT2 |
| 11 |
Danio rerio |
45.40 |
1 |
solute carrier family 6 (neurotransmitter transpor |
Top-ranked sequences
| organism | matching |
|---|
| Mus musculus |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVATTTIP 182
||||||||||||||||||||||||||||||#||||||||||||||||||
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVATTTIP 182
|
| Rattus norvegicus |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVATTTIP 182
|||| |||||||||| ||||||||||||||#||||||||||||||||||
Sbjct 127 NVSVAKGTLEHNNTPPVGWVNMSQSTVVLG#TDGIASVLPGSVATTTIP 174
|
| Macaca mulatta |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||||| |||||||||||||||||||#|||| |||||||||
Sbjct 177 NVSVGKGTLERNNTPAVGWVNMSQSTVVLG#TDGITSVLPGSVAT 220
|
| Bos taurus |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||||| |||||||||||||||||||#|||| |||||||||
Sbjct 134 NVSVGKGTLERNNTPAVGWVNMSQSTVVLG#TDGITSVLPGSVAT 177
|
| Homo sapiens |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||||| |||| ||||||||||||||#|||| |||||||||
Sbjct 133 NVSVGKGTLERNNTPVVGWVNMSQSTVVLG#TDGITSVLPGSVAT 176
|
| N/A |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||||| |||| ||||||||||||||#|||| |||||||||
Sbjct 133 NVSVGKGTLERNNTPVVGWVNMSQSTVVLG#TDGITSVLPGSVAT 176
|
| Pan troglodytes |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||||| |||| |||||+||||||||#|||| |||||||||
Sbjct 133 NVSVGKGTLERNNTPVVGWVNVSQSTVVLG#TDGITSVLPGSVAT 176
|
| Monodelphis domestica |
Query 137 SVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVATTTIP 182
| |||||| |+| | ||+||||||||||#|||| ||||||| ||+ |
Sbjct 134 SSGKGTLERNSTQAAGWINMSQSTVVLG#TDGITSVLPGSVTTTSTP 179
|
| Canis familiaris |
Query 137 SVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSVAT 178
|||||||| |+||| |||||||| ||||#|||| ||||||||+
Sbjct 242 SVGKGTLERNSTPAGGWVNMSQSAVVLG#TDGITSVLPGSVAS 283
|
| Gallus gallus |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSV 176
| ++|| ||| || + || +||||||||#||| ||||| |
Sbjct 191 NAALGKSTLEQNNAKST-WVTLSQSTVVLG#TDGNTSVLPGRV 231
|
| Danio rerio |
Query 135 NVSVGKGTLEHNNTPAVGWVNMSQSTVVLG#TDGIASVLPGSV 176
| | + ||||+ | +|||+|++||#||| |||||+|
Sbjct 110 NQSAVRIAAEHNNSTG-DWTSMSQTTIILG#TDGNTSVLPGTV 150
|
* References
[PubMed ID: 15081419] Ebihara S, Yamamoto T, Obata K, Yanagawa Y, Gene structure and alternative splicing of the mouse glycine transporter type-2. Biochem Biophys Res Commun. 2004 May 7;317(3):857-64.
