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XSB0516 : ras homolog gene family, member A [Canis lupus familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0038

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein NamesTransforming protein RhoA; Rho1; ras homolog gene family; member A; rho1 GTP-binding protein
Gene NamesRHOA; ARHA, RHO1; ARHA; RHO1; ras homolog gene family, member A
Gene Locus20; chromosome 20
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001003273 NM_001003273 403954 P24406 N/A N/A N/A cfa:403954

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 193 aa

Average Mass: 21.740 kDa

Monoisotopic Mass: 21.726 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Ras 1. 7180332.86.9e-97
--- cleavage 180 (inside Ras 7..180) ---

3. Sequence Information

Fasta Sequence: XSB0516.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] FEMATRAALQ180-ARRGKKKSGC

Gln180 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe171Glu172Met173Ala174Thr175Arg176Ala177Ala178Leu179Gln180
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala181Arg182Arg183Gly184Lys185Lys186Lys187Ser188Gly189Cys190

Sequence conservation (by blast)

* References

[PubMed ID: 18097951] Paschoud S, Citi S, Inducible overexpression of cingulin in stably transfected MDCK cells does not affect tight junction organization and gene expression. Mol Membr Biol. 2008 Jan;25(1):1-13.

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