XSB0581 : PREDICTED: similar to Neuromodulin (Axonal membrane protein GAP-43) (Growth associated protein 43) (PP46) (Neural phosphoprotein B-50) [Canis familiaris]
[ CaMP Format ]
This entry is computationally expanded from SB0067
* Basic Information
| Organism | Canis lupus familiaris (dog) |
| Protein Names | similar to Neuromodulin (Axonal membrane protein GAP-43) (Growth associated protein 43) (PP46) (Neural phosphoprotein B-50) |
| Gene Names | LOC478572; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 6 mRNAs, 140 ESTs, 16 Proteins |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 243 aa
Average Mass: 25.158 kDa
Monoisotopic Mass: 25.143 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| Neuromodulin_N 1. | 1 | 31 | 65.8 | 1.6e-16 |
| --- cleavage 4 (inside Neuromodulin_N 1..31) --- | ||||
| IQ 1. | 32 | 52 | 32.4 | 1.9e-06 |
| --- cleavage 40 (inside IQ 32..52) --- | ||||
| Neuromodulin 1. | 67 | 243 | 312.2 | 1.1e-90 |
3. Sequence Information
Fasta Sequence: XSB0581.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] AHKAATKIQA40-SFRGHITRKK
Ala40 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ala31 | His32 | Lys33 | Ala34 | Ala35 | Thr36 | Lys37 | Ile38 | Gln39 | Ala40 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser41 | Phe42 | Arg43 | Gly44 | His45 | Ile46 | Thr47 | Arg48 | Lys49 | Lys50 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| VEKNDEDQKIEQDGIKPEDKAHKAATKIQASFRGHITRKKLKGEKKGDAQAAEAEAKEKD |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 85.50 | 4 | N |
| 2 | Bos taurus | 85.50 | 3 | growth associated protein 43 |
| 3 | Macaca mulatta | 85.50 | 3 | PREDICTED: growth associated protein 43 isoform 2 |
| 4 | Felis catus | 85.50 | 2 | growth associated protein 43 |
| 5 | Canis familiaris | 85.50 | 2 | PREDICTED: similar to Neuromodulin (Axonal membran |
| 6 | Capra hircus | 85.50 | 2 | growth associated protein 43 |
| 7 | Saimiri boliviensis | 85.50 | 1 | growth associated protein 43 |
| 8 | Mus musculus | 85.10 | 2 | growth associated protein 43 |
| 9 | Rattus norvegicus | 85.10 | 1 | growth associated protein 43 |
| 10 | synthetic construct | 84.30 | 2 | growth associated protein 43 |
| 11 | Homo sapiens | 84.30 | 2 | growth associated protein 43 |
| 12 | Pongo pygmaeus | 84.30 | 1 | NEUM_PONPY Neuromodulin (Axonal membrane protein G |
| 13 | Monodelphis domestica | 79.70 | 3 | PREDICTED: similar to neuron growth-associated pro |
| 14 | Serinus canaria | 78.20 | 2 | NEUM_SERCA Neuromodulin (Axonal membrane protein G |
| 15 | Gallus gallus | 78.20 | 2 | PREDICTED: similar to growth-associated polypeptid |
| 16 | Lonchura striata | 78.20 | 1 | growth-associated protein 43 |
| 17 | Xenopus tropicalis | 73.60 | 2 | hypothetical protein LOC779658 |
| 18 | Danio rerio | 72.00 | 7 | Gap43 protein |
| 19 | Xenopus laevis | 71.20 | 2 | growth associated protein 43 |
| 20 | Tetraodon nigroviridis | 69.70 | 2 | unnamed protein product |
| 21 | Gillichthys mirabilis | 36.60 | 1 | AF419164_1 neurogranin |
| 22 | Drosophila melanogaster | 35.40 | 2 | igloo CG18285-PA, isoform A |
| 23 | Anopheles gambiae str. PEST | 35.00 | 2 | ENSANGP00000015620 |
| 24 | Tribolium castaneum | 35.00 | 1 | PREDICTED: similar to CG18285-PA, isoform A |
| 25 | Apis mellifera | 34.70 | 1 | PREDICTED: similar to igloo CG18285-PA, isoform A |
| 26 | Pan troglodytes | 34.30 | 1 | PREDICTED: similar to neurogranin |
| 27 | Aedes aegypti | 34.30 | 1 | conserved hypothetical protein |
| 28 | Drosophila pseudoobscura | 34.30 | 1 | GA14874-PA |
| 29 | Schistosoma japonicum | 32.70 | 1 | SJCHGC01496 protein |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Bos taurus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Macaca mulatta | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Felis catus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Canis familiaris | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Capra hircus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Saimiri boliviensis | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||||||||||||||||||#||||||||||| Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Mus musculus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||+|||||||||||||||#||||||||||| Sbjct 11 VEKNDEDQKIEQDGVKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Rattus norvegicus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||||||||||||+|||||||||||||||#||||||||||| Sbjct 11 VEKNDEDQKIEQDGVKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| synthetic construct | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |||||+||||||||||||||||||||||||#||||||||||| Sbjct 11 VEKNDDDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Homo sapiens | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |||||+||||||||||||||||||||||||#||||||||||| Sbjct 11 VEKNDDDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Pongo pygmaeus | Query 11 VEKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |||||+||||||||||||||||||||||||#||||||||||| Sbjct 11 VEKNDDDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |
| Monodelphis domestica | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |||||+ ||||||||||||||||||||||||#||||||||||| Sbjct 21 VEKNDDADQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 62 |
| Serinus canaria | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||++ ||||||||||||||||||||||||#||||||||||| Sbjct 4 VEKNEDGDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 45 |
| Gallus gallus | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||++ ||||||||||||||||||||||||#||||||||||| Sbjct 204 VEKNEDGDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 245 |
| Lonchura striata | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||++ ||||||||||||||||||||||||#||||||||||| Sbjct 11 VEKNEDGDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 52 |
| Xenopus tropicalis | Query 11 VEKN-DEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 |||| | |||||||| |||||||||||||||#|||||| |||| Sbjct 11 VEKNEDADQKIEQDGNKPEDKAHKAATKIQA#SFRGHIIRKKL 52 |
| Danio rerio | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||+| ||+|+|||||||+ ||||||||||#||||||||||+ Sbjct 11 VEKNEEADQEIKQDGIKPEENAHKAATKIQA#SFRGHITRKKM 52 |
| Xenopus laevis | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||++ ||||+||| |||||||||||||||#|||||| |||+ Sbjct 11 VEKNEDGDQKIDQDGNKPEDKAHKAATKIQA#SFRGHIIRKKM 52 |
| Tetraodon nigroviridis | Query 11 VEKNDE-DQKIEQDGI--KPEDKAHKAATKIQA#SFRGHITRKKL 51 ||||+| +||+|||| |||||||||||||||#||||||||||+ Sbjct 11 VEKNEEAEQKVEQDGTTNKPEDKAHKAATKIQA#SFRGHITRKKM 54 |
| Gillichthys mirabilis | Query 28 EDKAHKAATKIQA#SFRGHITRKKL 51 + +|++|| ||||# ||||+||||+ Sbjct 25 DPEANRAAAKIQA#GFRGHMTRKKM 48 |
| Drosophila melanogaster | Query 18 QKIEQDGIKPEDKAHKAATKIQA#SFRGHITRK 49 ++++ | || +||||||||#||||| ||| Sbjct 206 EELDIDLTDPE--LNKAATKIQA#SFRGHKTRK 235 |
| Anopheles gambiae str. PEST | Query 12 EKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRK 49 +| |+ |+ | + + ||||+||||#||||| || Sbjct 38 KKVAEELDIDMD----DPELHKAASKIQA#SFRGHKVRK 71 |
| Tribolium castaneum | Query 12 EKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKKL 51 | |++||+ + + |||||||#|||||+ ||++ Sbjct 89 ETEPTQQELEQEFRSDDHELCHAATKIQA#SFRGHMIRKQM 128 Query 12 EKNDEDQKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKK 50 +||+|+ |+ + +||| ||||#|||||+ ||+ Sbjct 141 KKNEEELDIDLS----DPDLNKAAVKIQA#SFRGHMVRKE 175 |
| Apis mellifera | Query 11 VEKNDEDQKIEQDGIKPEDK-AHKAATKIQA#SFRGHITRKKL 51 +|+ +| | +|| | |||||||||#||||| |+++ Sbjct 75 MEEKAKDAMNELEGIDLTDPDLHKAATKIQA#SFRGHKVRQEV 116 Query 18 QKIEQDGIKPEDKAHKAATKIQA#SFRGHITRKK 50 ++++|+ + + +|||||||#|||||++||+ Sbjct 22 EQLQQEFRADDKELCEAATKIQA#SFRGHMSRKE 54 |
| Pan troglodytes | Query 31 AHKAATKIQA#SFRGHITRKKL 51 |+ || ||||#|||||+ |||+ Sbjct 156 ANAAAAKIQA#SFRGHMARKKI 176 |
| Aedes aegypti | Query 12 EKNDEDQK------------IEQDGIKPED-KAHKAATKIQA#SFRGHITRK 49 +|+||| | |+ | +| + ||||+||||#||||| |+ Sbjct 10 KKDDEDDKKDVNIDELTRKVAEELDIDMDDPELHKAASKIQA#SFRGHKVRR 60 |
| Drosophila pseudoobscura | Query 18 QKIEQDGIKPEDKAHKAATKIQA#SFRGHITRK 49 ++++ | || +||||||||#||||| ||+ Sbjct 206 EELDIDLTDPE--LNKAATKIQA#SFRGHKTRR 235 |
| Schistosoma japonicum | Query 29 DKAHKAATKIQA#SFRGHITRKK 50 || |||||||# +||+ |||| Sbjct 38 DKESLAATKIQA#GYRGYCTRKK 59 |
[Site 2] MLCC4-MRRTKQVEKN
Cys4 Met
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | Met1 | Leu2 | Cys3 | Cys4 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Met5 | Arg6 | Arg7 | Thr8 | Lys9 | Gln10 | Val11 | Glu12 | Lys13 | Asn14 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MLCCMRRTKQVEKNDEDQKIEQDGIKPEDKAHKA |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 75.10 | 4 | N |
| 2 | Bos taurus | 75.10 | 2 | growth associated protein 43 |
| 3 | Macaca mulatta | 75.10 | 2 | PREDICTED: growth associated protein 43 isoform 2 |
| 4 | Canis familiaris | 75.10 | 1 | PREDICTED: similar to Neuromodulin (Axonal membran |
| 5 | Felis catus | 75.10 | 1 | growth associated protein 43 |
| 6 | Rattus norvegicus | 74.70 | 1 | growth associated protein 43 |
| 7 | Mus musculus | 74.70 | 1 | growth associated protein 43 |
| 8 | synthetic construct | 73.90 | 3 | growth associated protein 43 |
| 9 | Pongo pygmaeus | 73.90 | 1 | NEUM_PONPY Neuromodulin (Axonal membrane protein G |
| 10 | Homo sapiens | 73.90 | 1 | growth associated protein 43 |
| 11 | Lonchura striata | 67.80 | 1 | growth-associated protein 43 |
| 12 | Xenopus tropicalis | 65.50 | 1 | hypothetical protein LOC779658 |
| 13 | Xenopus laevis | 63.90 | 2 | growth associated protein 43 |
| 14 | Saimiri boliviensis | 62.80 | 1 | growth associated protein 43 |
| 15 | Danio rerio | 58.50 | 2 | Gap43 protein |
| 16 | Capra hircus | 57.00 | 1 | growth associated protein 43 |
| 17 | Tetraodon nigroviridis | 56.20 | 1 | unnamed protein product |
| 18 | Serinus canaria | 51.60 | 1 | NEUM_SERCA Neuromodulin (Axonal membrane protein G |
| 19 | Monodelphis domestica | 47.40 | 1 | PREDICTED: similar to neuron growth-associated pro |
| 20 | Gallus gallus | 45.80 | 1 | PREDICTED: similar to growth-associated polypeptid |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||||||||||||||||||||| Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Bos taurus | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||||||||||||||||||||| Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Macaca mulatta | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||||||||||||||||||||| Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Canis familiaris | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||||||||||||||||||||| Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Felis catus | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||||||||||||||||||||| Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Rattus norvegicus | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#||||||||||||||||||||+||||||||| Sbjct 1 MLCC#MRRTKQVEKNDEDQKIEQDGVKPEDKAHKA 34 |
| Mus musculus | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#||||||||||||||||||||+||||||||| Sbjct 1 MLCC#MRRTKQVEKNDEDQKIEQDGVKPEDKAHKA 34 |
| synthetic construct | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||+|||||||||||||||||| Sbjct 1 MLCC#MRRTKQVEKNDDDQKIEQDGIKPEDKAHKA 34 |
| Pongo pygmaeus | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||+|||||||||||||||||| Sbjct 1 MLCC#MRRTKQVEKNDDDQKIEQDGIKPEDKAHKA 34 |
| Homo sapiens | Query 1 MLCC#MRRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||||+|||||||||||||||||| Sbjct 1 MLCC#MRRTKQVEKNDDDQKIEQDGIKPEDKAHKA 34 |
| Lonchura striata | Query 1 MLCC#MRRTKQVEKNDE-DQKIEQDGIKPEDKAHKA 34 ||||#||||||||||++ |||||||||||||||||| Sbjct 1 MLCC#MRRTKQVEKNEDGDQKIEQDGIKPEDKAHKA 35 |
| Xenopus tropicalis | Query 1 MLCC#MRRTKQVEKN-DEDQKIEQDGIKPEDKAHKA 34 ||||#|||||||||| | |||||||| ||||||||| Sbjct 1 MLCC#MRRTKQVEKNEDADQKIEQDGNKPEDKAHKA 35 |
| Xenopus laevis | Query 1 MLCC#MRRTKQVEKNDE-DQKIEQDGIKPEDKAHKA 34 ||||#||||||||||++ ||||+||| ||||||||| Sbjct 1 MLCC#MRRTKQVEKNEDGDQKIDQDGNKPEDKAHKA 35 |
| Saimiri boliviensis | Query 6 RRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 ||||||||||||||||||||||||||||| Query 6 RRTKQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Danio rerio | Query 1 MLCC#MRRTKQVEKNDE-DQKIEQDGIKPEDKAHKA 34 ||||#+|||| ||||+| ||+|+|||||||+ |||| Sbjct 1 MLCC#IRRTKPVEKNEEADQEIKQDGIKPEENAHKA 35 |
| Capra hircus | Query 9 KQVEKNDEDQKIEQDGIKPEDKAHKA 34 |||||||||||||||||||||||||| Query 9 KQVEKNDEDQKIEQDGIKPEDKAHKA 34 |
| Tetraodon nigroviridis | Query 1 MLCC#MRRTKQVEKNDE-DQKIEQDGI--KPEDKAHKA 34 ||||#+|||| ||||+| +||+|||| ||||||||| Sbjct 1 MLCC#IRRTKPVEKNEEAEQKVEQDGTTNKPEDKAHKA 37 |
| Serinus canaria | Query 8 TKQVEKNDE-DQKIEQDGIKPEDKAHKA 34 |||||||++ |||||||||||||||||| Sbjct 1 TKQVEKNEDGDQKIEQDGIKPEDKAHKA 28 |
| Monodelphis domestica | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKA 34 |||||+ |||||||||||||||||| Sbjct 21 VEKNDDADQKIEQDGIKPEDKAHKA 45 |
| Gallus gallus | Query 11 VEKNDE-DQKIEQDGIKPEDKAHKA 34 ||||++ |||||||||||||||||| Sbjct 204 VEKNEDGDQKIEQDGIKPEDKAHKA 228 |
* References
None.