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XSB0627 : spectrin, beta, erythrocytic (includes spherocytosis, clinical type I) variant [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0052

* Basic Information

OrganismHomo sapiens (human)
Protein NamesSpectrin, beta, erythrocytic (Includes spherocytosis, clinical type I) variant; spectrin; beta; erythrocytic (includes spherocytosis; clinical type I) variant; SubName: Full=Spectrin; erythrocytic; Includes spherocytosis; clinical type I
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
BAD92652 N/A N/A Q59FP5 N/A N/A N/A hsa:6710

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 2332 aa

Average Mass: 268.239 kDa

Monoisotopic Mass: 268.073 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
CH 1. 59162121.72.4e-33
CH 2. 178282148.61.9e-41
Spectrin 1. 30641673.76.9e-19
Spectrin 2. 426530106.11.2e-28
Spectrin 3. 53263996.59.2e-26
Spectrin 4. 641745125.61.6e-34
Spectrin 5. 74785099.51.2e-26
Spectrin 6. 85295675.91.5e-19
Spectrin 7. 958106386.01.3e-22
Spectrin 8. 1065117097.06.4e-26
Spectrin 9. 1172127627.36.5e-05
Spectrin 10. 12781381108.03.3e-29
Spectrin 11. 1385148028.33.2e-05
Spectrin 12. 1482158677.74.2e-20
Spectrin 13. 1588169298.32.6e-26
Spectrin 14. 16941799114.34e-31
Spectrin 15. 1801190586.49.9e-23
Spectrin 16. 19072011102.41.6e-27
Spectrin 17. 2013209917.60.0011
--- cleavage 2065 (inside Spectrin 2013..2099) ---
PH 1. 2183229271.04.3e-18

3. Sequence Information

Fasta Sequence: XSB0627.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] EAFEKSTASW2065-AERFAALEKP

Trp2065 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu2056Ala2057Phe2058Glu2059Lys2060Ser2061Thr2062Ala2063Ser2064Trp2065
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala2066Glu2067Arg2068Phe2069Ala2070Ala2071Leu2072Glu2073Lys2074Pro2075

Sequence conservation (by blast)

* References

None.