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XSB0638 : integrin beta chain, beta 2 precursor variant [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0002

* Basic Information

OrganismHomo sapiens (human)
Protein NamesIntegrin beta; integrin beta chain; beta 2 precursor variant
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
BAD96225 N/A N/A Q53HS5 N/A N/A N/A hsa:

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 769 aa

Average Mass: 84.775 kDa

Monoisotopic Mass: 84.719 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Integrin_beta 1. 324471048.00
EGF_2 1. 44948118.70.02
EGF_2 2. 49753411.80.13
EGF_2 3. 54157316.00.042
EGF_2 4. 58261225.70.00019
Integrin_B_tail 1. 622700132.01.8e-36
Integrin_b_cyt 1. 72476887.83.9e-23
--- cleavage 762 (inside Integrin_b_cyt 724..768) ---
--- cleavage 760 (inside Integrin_b_cyt 724..768) ---

3. Sequence Information

Fasta Sequence: XSB0638.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] LFKSATTTVM762-NPKFAES

Met762 Asn

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Leu753Phe754Lys755Ser756Ala757Thr758Thr759Thr760Val761Met762
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Asn763Pro764Lys765Phe766Ala767Glu768Ser769---

Sequence conservation (by blast)

[Site 2] NPLFKSATTT760-VMNPKFAES

Thr760 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn751Pro752Leu753Phe754Lys755Ser756Ala757Thr758Thr759Thr760
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val761Met762Asn763Pro764Lys765Phe766Ala767Glu768Ser769-

Sequence conservation (by blast)

* References

[PubMed ID: 8125298] Maruyama K, Sugano S, Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides. Gene. 1994 Jan 28;138(1-2):171-4.

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