XSB0655 : protein kinase C, beta [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0039
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Protein kinase C beta type; PKC-beta; PKC-B; 2.7.11.13; protein kinase C; beta; protein kinase C beta-II; beta 1 |
| Gene Names | Prkcb; Pkcb, Prkcb1; Pkcb; Prkcb1; protein kinase C, beta |
| Gene Locus | 7 60.0 cM; chromosome 7 |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 673 aa
Average Mass: 76.894 kDa
Monoisotopic Mass: 76.844 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| C1_1 1. | 37 | 89 | 80.1 | 8.2e-21 |
| C1_1 2. | 102 | 154 | 97.3 | 5.4e-26 |
| C2 1. | 173 | 260 | 128.3 | 2.5e-35 |
| --- cleavage 311 --- | ||||
| --- cleavage 320 --- | ||||
| Pkinase 1. | 342 | 600 | 262.2 | 1.2e-75 |
| Pkinase_C 1. | 620 | 665 | 55.6 | 1.9e-13 |
3. Sequence Information
Fasta Sequence: XSB0655.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] RQKFERAKIG311-QGTKAPEEKT
Gly311 
Gln
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Arg302 | Gln303 | Lys304 | Phe305 | Glu306 | Arg307 | Ala308 | Lys309 | Ile310 | Gly311 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gln312 | Gly313 | Thr314 | Lys315 | Ala316 | Pro317 | Glu318 | Glu319 | Lys320 | Thr321 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| EGEYFNVPVPPEGSEGNEELRQKFERAKIGQGTKAPEEKTANTISKFDNNGNRDRMKLTD |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 126.00 | 10 | - |
| 2 | Mus musculus | 126.00 | 4 | protein kinase C, beta 1 |
| 3 | Rattus norvegicus | 126.00 | 4 | protein kinase C, beta |
| 4 | Oryctolagus cuniculus | 123.00 | 3 | unnamed protein product |
| 5 | Macaca mulatta | 120.00 | 6 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 6 | Canis familiaris | 120.00 | 2 | PREDICTED: similar to Protein kinase C, beta type |
| 7 | Bos taurus | 119.00 | 3 | protein kinase C, beta |
| 8 | Homo sapiens | 118.00 | 9 | protein kinase C, beta isoform 2 |
| 9 | Monodelphis domestica | 116.00 | 3 | PREDICTED: similar to Protein kinase C beta type ( |
| 10 | Gallus gallus | 110.00 | 3 | PREDICTED: similar to protein kinase C beta-1 |
| 11 | Latimeria chalumnae | 102.00 | 2 | protein kinase C beta 1 |
| 12 | Protopterus dolloi | 100.00 | 2 | protein kinase C beta 1 |
| 13 | Tetraodon nigroviridis | 95.10 | 3 | unnamed protein product |
| 14 | Danio rerio | 92.80 | 7 | protein kinase C, beta 1 |
| 15 | Scyliorhinus canicula | 89.40 | 2 | protein kinase C |
| 16 | Petromyzon marinus | 63.50 | 1 | protein kinase C |
| 17 | synthetic construct | 56.20 | 1 | protein kinase C alpha |
| 18 | Takifugu rubripes | 53.90 | 1 | protein kinase C, alpha type |
| 19 | Xenopus tropicalis | 52.80 | 1 | hypothetical protein LOC780209 |
| 20 | Xenopus laevis | 50.40 | 1 | protein kinase C, alpha |
| 21 | Myxine glutinosa | 46.60 | 1 | protein kinase C |
| 22 | Caenorhabditis briggsae | 39.70 | 1 | Hypothetical protein CBG16150 |
| 23 | Aplysia californica | 35.80 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 24 | Branchiostoma lanceolatum | 32.30 | 1 | protein kinase C |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 |
| Mus musculus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 |
| Rattus norvegicus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 |
| Oryctolagus cuniculus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||||#|||| ||||| ||||||||||||||||||| Sbjct 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKTPEEKTTNTISKFDNNGNRDRMKLTD 341 |
| Macaca mulatta | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||| #|||| ||||| ||+|||||||||||||||| Sbjct 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIS#QGTKVPEEKTTNTVSKFDNNGNRDRMKLTD 341 |
| Canis familiaris | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||| #|||||||||| ||||| ||||||||||||| Sbjct 274 EGEYFNVPVPPEGSEGNEELRQKFERAKIS#QGTKAPEEKTTNTISKLDNNGNRDRMKLTD 333 |
| Bos taurus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||||||||||||||||||# | | ||||| ||||||||||||||||||| Sbjct 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#PGPKTPEEKTTNTISKFDNNGNRDRMKLTD 341 |
| Homo sapiens | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||||| ||||||||||||| #|||| ||||| ||+|||||||||||||||| Sbjct 282 EGEYFNVPVPPEGSEANEELRQKFERAKIS#QGTKVPEEKTTNTVSKFDNNGNRDRMKLTD 341 |
| Monodelphis domestica | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| ||||||||||||||||#|||| |||||| ||| ||||||||||||| Sbjct 279 EGEYFNVPVPPEGEEGNEELRQKFERAKIG#QGTKVTEEKTANAISKIDNNGNRDRMKLTD 338 |
| Gallus gallus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| ||||||||||||||||# |+|| +||| | ||||||||+||||||+| Sbjct 281 EGEYFNVPVPPEGEEGNEELRQKFERAKIG#TGSKAADEKTTNAISKFDNNGSRDRMKLSD 340 |
| Latimeria chalumnae | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| |||||||+||||||||# |+|| |+| |+ ||| |||||||+||+| Sbjct 204 EGEYFNVPVPPEGEEGNEELRKKFERAKIG#PGSKATEDKVKNSSSKFGNNGNRDRIKLSD 263 |
| Protopterus dolloi | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| ||||||||||||||||# | +| |+| || +||||||||||+||+| Sbjct 213 EGEYFNVPVPPEGEEGNEELRQKFERAKIG#PGAEAAEDKIANA-AKFDNNGNRDRVKLSD 271 |
| Tetraodon nigroviridis | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| ||||||||||||||||# | | + |+|| |+||+|||+||||| | Sbjct 218 EGEYFNVPVPPEGEEGNEELRQKFERAKIG#PG-KNTDGKSANAASRFDSNGNQDRMKLAD 276 |
| Danio rerio | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||||||||||| ||||||||||||||| # | + ++| |||||+|||||||||+| Sbjct 281 EGEYFNVPVPPEGEEGNEELRQKFERAKI-#-GPSKTDGSSSNAISKFDSNGNRDRMKLSD 338 |
| Scyliorhinus canicula | Query 282 EGEYFNVPVPPE-GSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLT 340 ||||+||||||| ||||||||||||||+||# |+|| ||| +++ || | ||||||||| Sbjct 202 EGEYYNVPVPPEEDSEGNEELRQKFERARIG#PGSKAAEEKRSSSWSKID-NGNRDRMKLA 260 Query 341 D 341 | Query 341 D 341 |
| Petromyzon marinus | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTK--APEEKTANTISKFDNNGNRDRMKL 339 ||||+|||+ |+ +|+ |+|+|||+|++|# | | +|+ ||++| || | ||+| Sbjct 212 EGEYYNVPIAPDIEDGDTEMRRKFEKARLG#PSVKPRASDERRANSLSAILNNANVDRVKA 271 Query 340 TD 341 | Sbjct 272 DD 273 |
| synthetic construct | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||+| ||| |||||||+||+|# | + + + + + | ||+|||| Sbjct 282 EGEYYNVPIPEGDEEGNMELRQKFEKAKLG#---PAGNKVISPSEDRKQPSNNLDRVKLTD 338 |
| Takifugu rubripes | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||+| | + | |||||||+||+|#|| | | +|| ||++| | Sbjct 280 EGEYYNVPIP-EVDDVNLELRQKFEKAKLG#QGKKVITPSDHRRFSL--PSGNMDRVRLND 336 |
| Xenopus tropicalis | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||+| | +|| |||||||+||+|# | +| | | ++||| Sbjct 286 EGEYYNVPIPEEEDDGNIELRQKFEKAKLG#PAGNKVISPTDERRPYVPSN-NIDSVRLTD 344 |
| Xenopus laevis | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||+| | +|| |||||||+||+|# | +| | | ++||| Sbjct 286 EGEYYNVPIP-EADDGNLELRQKFEKAKLG#PAGNKVINPTGERRPYIPSN-NIDSIRLTD 343 |
| Myxine glutinosa | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||| ||| || ||||+ +|++| #+ | + + | + ||+ | | Sbjct 203 EGEYYNVPVAPEGEEG-LELRQRLQRSQIA#RSDKNKQSPAKDQPSDSASLSGLDRVNLED 261 |
| Caenorhabditis briggsae | Query 282 EGEYFNVPVPPEGSEGNEELRQKF-ERAKIG#QGTKA--PEEKTANTISKFDNNGNRDRMK 338 |||++|+ + || | |++|+| + || #+ + | | | | | | ||| +| Sbjct 352 EGEFYNINITPEYDEDMEKVRKKMNDNFKIS#RDSSAGKPRESTPRATSTSLTNTNRDVIK 411 Query 339 LTD 341 +| Sbjct 412 ASD 414 |
| Aplysia californica | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFD 329 |||++ ||| + +| +|++ | |+ | # + || +|| | Sbjct 266 EGEFYGVPVTDDITESIQEIKSKMHRSSIS#SEKRYPEPDKVQNMSKQD 313 |
| Branchiostoma lanceolatum | Query 282 EGEYFNVPVPPEGSEGNEELRQKFERAKIG#QGTKAPEEKTANTISKFDNNGNRDRMKLTD 341 ||||+|||+ | | +|++ ++ |+ #+ | ++ |+ | |+ | || | Sbjct 213 EGEYYNVPIADE-EENVAKLKEHLQKQKLD#EQRKQKSKR-----SEECNIGSLDHMKAAD 266 |
[Site 2] GQGTKAPEEK320-TANTISKFDN
Lys320 Thr
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Gly311 | Gln312 | Gly313 | Thr314 | Lys315 | Ala316 | Pro317 | Glu318 | Glu319 | Lys320 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr321 | Ala322 | Asn323 | Thr324 | Ile325 | Ser326 | Lys327 | Phe328 | Asp329 | Asn330 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| PPEGSEGNEELRQKFERAKIGQGTKAPEEKTANTISKFDNNGNRDRMKLTDFNFLMVLGK |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 125.00 | 10 | - |
| 2 | Rattus norvegicus | 125.00 | 4 | protein kinase C, beta |
| 3 | Mus musculus | 125.00 | 4 | protein kinase C, beta 1 |
| 4 | Oryctolagus cuniculus | 122.00 | 3 | unnamed protein product |
| 5 | Macaca mulatta | 119.00 | 6 | PREDICTED: protein kinase C, beta 1 isoform 5 |
| 6 | Canis familiaris | 119.00 | 3 | PREDICTED: similar to Protein kinase C, beta type |
| 7 | Homo sapiens | 117.00 | 8 | protein kinase C, beta isoform 2 |
| 8 | Bos taurus | 117.00 | 3 | protein kinase C, beta |
| 9 | Monodelphis domestica | 114.00 | 3 | PREDICTED: similar to Protein kinase C beta type ( |
| 10 | Gallus gallus | 108.00 | 3 | PREDICTED: similar to protein kinase C beta-1 |
| 11 | Latimeria chalumnae | 100.00 | 2 | protein kinase C beta 1 |
| 12 | Protopterus dolloi | 99.00 | 2 | protein kinase C beta 1 |
| 13 | Tetraodon nigroviridis | 93.60 | 2 | unnamed protein product |
| 14 | Danio rerio | 91.30 | 6 | protein kinase C, beta 1 |
| 15 | Scyliorhinus canicula | 90.50 | 2 | protein kinase C |
| 16 | Petromyzon marinus | 63.90 | 1 | protein kinase C |
| 17 | synthetic construct | 57.40 | 1 | protein kinase C alpha |
| 18 | Takifugu rubripes | 55.10 | 1 | protein kinase C, alpha type |
| 19 | Xenopus laevis | 51.60 | 1 | protein kinase C, alpha |
| 20 | Xenopus tropicalis | 50.80 | 1 | hypothetical protein LOC780209 |
| 21 | Caenorhabditis briggsae | 43.10 | 1 | Hypothetical protein CBG16150 |
| 22 | Myxine glutinosa | 40.80 | 1 | protein kinase C |
| 23 | Branchiostoma lanceolatum | 35.80 | 1 | protein kinase C |
| 24 | Aplysia californica | 35.80 | 1 | KPC1_APLCA Calcium-dependent protein kinase C (APL |
| 25 | Aedes aegypti | 35.00 | 1 | protein kinase c |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Rattus norvegicus | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Mus musculus | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Oryctolagus cuniculus | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||||||||||||||||||||||||| ||||#| |||||||||||||||||||||||||||| Sbjct 291 PPEGSEGNEELRQKFERAKIGQGTKTPEEK#TTNTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Macaca mulatta | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||||||||||||||||||| |||| ||||#| ||+||||||||||||||||||||||||| Sbjct 291 PPEGSEGNEELRQKFERAKISQGTKVPEEK#TTNTVSKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Canis familiaris | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||||||||||||||||||| |||||||||#| ||||| |||||||||||||||||||||| Sbjct 283 PPEGSEGNEELRQKFERAKISQGTKAPEEK#TTNTISKLDNNGNRDRMKLTDFNFLMVLGK 342 |
| Homo sapiens | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||||| ||||||||||||| |||| ||||#| ||+||||||||||||||||||||||||| Sbjct 291 PPEGSEANEELRQKFERAKISQGTKVPEEK#TTNTVSKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Bos taurus | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||||||||||||||||||||| | | ||||#| |||||||||||||||||||||||||||| Sbjct 291 PPEGSEGNEELRQKFERAKIGPGPKTPEEK#TTNTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |
| Monodelphis domestica | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||||||||||||||| |||#||| ||| |||||||||||||||||||||| Sbjct 288 PPEGEEGNEELRQKFERAKIGQGTKVTEEK#TANAISKIDNNGNRDRMKLTDFNFLMVLGK 347 |
| Gallus gallus | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||||||||||| |+|| +||#| | ||||||||+||||||+|||||||||| Sbjct 290 PPEGEEGNEELRQKFERAKIGTGSKAADEK#TTNAISKFDNNGSRDRMKLSDFNFLMVLGK 349 |
| Latimeria chalumnae | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||+|||||||| |+|| |+|# |+ ||| |||||||+||+|||||||||| Sbjct 213 PPEGEEGNEELRKKFERAKIGPGSKATEDK#VKNSSSKFGNNGNRDRIKLSDFNFLMVLGK 272 |
| Protopterus dolloi | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||||||||||| | +| |+|# || +||||||||||+||+|||||||||| Sbjct 222 PPEGEEGNEELRQKFERAKIGPGAEAAEDK#IANA-AKFDNNGNRDRVKLSDFNFLMVLGK 280 |
| Tetraodon nigroviridis | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||||||||||| | | + |#+|| |+||+|||+||||| |||||||||| Sbjct 227 PPEGEEGNEELRQKFERAKIGPG-KNTDGK#SANAASRFDSNGNQDRMKLADFNFLMVLGK 285 |
| Danio rerio | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 |||| |||||||||||||||| + #++| |||||+|||||||||+|||||||||| Sbjct 290 PPEGEEGNEELRQKFERAKIGPSKT--DGS#SSNAISKFDSNGNRDRMKLSDFNFLMVLGK 347 |
| Scyliorhinus canicula | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 | | ||||||||||||||+|| |+|| |||# +++ || | ||||||||| |||||||||| Sbjct 212 PEEDSEGNEELRQKFERARIGPGSKAAEEK#RSSSWSKID-NGNRDRMKLADFNFLMVLGK 270 |
| Petromyzon marinus | Query 292 PEGSEGNEELRQKFERAKIGQGTK--APEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLG 349 |+ +|+ |+|+|||+|++| | | +|+# ||++| || | ||+| ||||||||| Sbjct 222 PDIEDGDTEMRRKFEKARLGPSVKPRASDER#RANSLSAILNNANVDRVKADDFNFLMVLG 281 Query 350 K 350 | Query 350 K 350 |
| synthetic construct | Query 292 PEGSE-GNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||| | || |||||||+||+| | + # + + + + | ||+||||||||||||| Sbjct 291 PEGDEEGNMELRQKFEKAKLGP---AGNKV#ISPSEDRKQPSNNLDRVKLTDFNFLMVLGK 347 |
| Takifugu rubripes | Query 292 PEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 || + | |||||||+||+||| | # | +|| ||++| ||||| +||| Sbjct 289 PEVDDVNLELRQKFEKAKLGQGKKVITPS#DHRRFSL--PSGNMDRVRLNDFNFLALLGK 345 |
| Xenopus laevis | Query 292 PEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 || +|| |||||||+||+| #| +| | | ++|||| ||||||| Sbjct 295 PEADDGNLELRQKFEKAKLGPAGNKVINP#TGERRPYIPSN-NIDSIRLTDFCFLMVLGK 352 |
| Xenopus tropicalis | Query 291 PPEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 | | +|| |||||||+||+| #| +| | | ++||||+||||||| Sbjct 295 PEEEDDGNIELRQKFEKAKLGPAGNKVISP#TDERRPYVPSN-NIDSVRLTDFSFLMVLGK 353 |
| Caenorhabditis briggsae | Query 292 PEGSEGNEELRQKF-ERAKIGQGTKA--PEEK#TANTISKFDNNGNRDRMKLTDFNFLMVL 348 || | |++|+| + || + + | | | #| | | ||| +| +||||| || Sbjct 362 PEYDEDMEKVRKKMNDNFKISRDSSAGKPRES#TPRATSTSLTNTNRDVIKASDFNFLTVL 421 Query 349 GK 350 || Query 349 GK 350 |
| Myxine glutinosa | Query 292 PEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 ||| || | |||+ +|++| + | + # + | + ||+ | || || |||| Sbjct 213 PEGEEGLE-LRQRLQRSQIARSDKNKQSP#AKDQPSDSASLSGLDRVNLEDFVFLTVLGK 270 |
| Branchiostoma lanceolatum | Query 296 EGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 | +|++ ++ |+ + | ++#+ | |+ | || |||||||||| Sbjct 226 ENVAKLKEHLQKQKLDEQRKQKSKR#SEEC-----NIGSLDHMKAADFNFLMVLGK 275 |
| Aplysia californica | Query 295 SEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 +| +|++ | |+ | + || # +|| +| ++ +||||| |||| Sbjct 279 TESIQEIKSKMHRSSISSEKRYPEPD#KVQNMSK------QDIVRASDFNFLTVLGK 328 |
| Aedes aegypti | Query 292 PEGSEGNEELRQKFERAKIGQGTKAPEEK#TANTISKFDNNGNRDRMKLTDFNFLMVLGK 350 | || + ++ | + | ||| # + | | +| ++ ||||||||||| Sbjct 237 PVPEEGTDLVQLKSQMRKTSISKKAPVLC#DKDVPH---NMGKKDVIRATDFNFLMVLGK 292 |
* References
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