XSB0722 : PREDICTED: similar to Neurotensin/neuromedin N precursor [Canis familiaris]
[ CaMP Format ]
This entry is computationally expanded from SB0034
* Basic Information
| Organism | Canis lupus familiaris (dog) |
| Protein Names | Neurotensin/neuromedin N; Large neuromedin N; NmN-125; Neuromedin N; NmN; NN; Neurotensin; NT; NT-tail; Tail peptide; similar to Neurotensin/neuromedin N precursor |
| Gene Names | LOC611687; NTS; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 1 mRNA, 5 ESTs, 1 Protein |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 170 aa
Average Mass: 19.863 kDa
Monoisotopic Mass: 19.850 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| Pro-NT_NN 1. | 2 | 170 | 473.9 | 2.3e-139 |
| --- cleavage 153 (inside Pro-NT_NN 2..170) --- |
3. Sequence Information
Fasta Sequence: XSB0722.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] IPYILKRQLY153-ENKPRRPYIL
Tyr153 
Glu
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Ile144 | Pro145 | Tyr146 | Ile147 | Leu148 | Lys149 | Arg150 | Gln151 | Leu152 | Tyr153 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Glu154 | Asn155 | Lys156 | Pro157 | Arg158 | Arg159 | Pro160 | Tyr161 | Ile162 | Leu163 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
EDVLDAGNDKNEKEEVIKRKIPYILKRQLYENKPRRPYILKRGSYYY
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Contains: Large neuromedin N (NmN-125); Neuromedin N (NmN) (NN); Neurotensin (NT); Tail peptide |
100.00 |
2 |
NEUT_BOVIN Neurotensin/neuromedin N precursor |
| 2 |
Bos taurus |
100.00 |
1 |
neurotensin |
| 3 |
Canis familiaris |
100.00 |
1 |
PREDICTED: similar to Neurotensin/neuromedin N pre |
| 4 |
Pan troglodytes |
95.90 |
3 |
PREDICTED: neurotensin/neuromedin N isoform 3 |
| 5 |
Macaca mulatta |
95.90 |
1 |
PREDICTED: neurotensin |
| 6 |
Macaca fascicularis |
95.90 |
1 |
hypothetical protein |
| 7 |
Mus musculus |
94.40 |
1 |
neurotensin |
| 8 |
Homo sapiens |
93.20 |
3 |
neurotensin/neuromedin N preproprotein |
| 9 |
N/A |
91.70 |
1 |
- |
| 10 |
Rattus norvegicus |
91.70 |
1 |
PREDICTED: similar to Neurotensin/neuromedin N pre |
| 11 |
Monodelphis domestica |
70.50 |
1 |
PREDICTED: similar to Neurotensin/neuromedin N pre |
| 12 |
Xenopus laevis |
64.70 |
1 |
MGC84018 protein |
| 13 |
Gallus gallus |
61.20 |
1 |
PREDICTED: similar to Neurotensin/neuromedin N pre |
Top-ranked sequences
| organism | matching |
|---|
| Contains: Large neuromedin N (NmN-125); Neuromedin N (NmN) (NN); Neurotensin (NT); Tail peptide |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|||||||||||||||||||||||||||#|||||||||||||||||
Sbjct 123 EDILDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 169
|
| Bos taurus |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|||||||||||||||||||||||||||#|||||||||||||||||
Sbjct 124 EDILDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
|
| Canis familiaris |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||||||||||||||||||||||||||||||#|||||||||||||||||
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
|
| Pan troglodytes |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||||||||||||||||||||||||#|||||||||||| ||||
Sbjct 124 EDILDTGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRDSYYY 170
|
| Macaca mulatta |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||||||||||||||||||||||||#|||||||||||| ||||
Sbjct 124 EDILDTGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRDSYYY 170
|
| Macaca fascicularis |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||||||||||||||||||||||||#|||||||||||| ||||
Sbjct 124 EDILDTGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRDSYYY 170
|
| Mus musculus |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| |||||||||||||||||||||||#|||||||||||||||||
Sbjct 123 EDILDNVNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 169
|
| Homo sapiens |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||||| ||||||||||||||||||#|||||||||||| ||||
Sbjct 124 EDILDTGNDKNGKEEVIKRKIPYILKRQLY#ENKPRRPYILKRDSYYY 170
|
| N/A |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||+| |||||||||||||||||||#|||||||||||| ||||
Sbjct 79 EDILDHGNEKTEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRASYYY 125
|
| Rattus norvegicus |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
||+|| ||+| |||||||||||||||||||#|||||||||||| ||||
Sbjct 123 EDILDHGNEKTEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRASYYY 169
|
| Monodelphis domestica |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYYY 170
+|+|+ || |||||+||| |||||||++# || |||||||| | ||
Sbjct 119 DDILETGNLNREKEEVMKRKTPYILKRQIH#VNKARRPYILKRSSSYY 165
|
| Xenopus laevis |
Query 125 DVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYY 169
| |+ + +||+| |||| ||||||| |# +| ||||||||||||
Sbjct 122 DYLEPNSPNSEKDEPIKRKTPYILKRQTY#VSKARRPYILKRGSYY 166
|
| Gallus gallus |
Query 124 EDVLDAGNDKNEKEEVIKRKIPYILKRQLY#ENKPRRPYILKRGSYY 169
+| | | ||| ++||| ||||||||+# || |||||||| |||
Sbjct 120 QDAFDLENSSQEKE-IMKRKNPYILKRQLH#VNKARRPYILKRSSYY 164
|
