logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0752 : PREDICTED: similar to neurofibromin 2 isoform 7 isoform 8 [Canis familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0009

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein Namessimilar to neurofibromin 2 isoform 7 isoform 8
Gene NamesLOC477535; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 11 mRNAs, 31 ESTs, 107 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_865488 XM_860395 477535 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 508 aa

Average Mass: 59.217 kDa

Monoisotopic Mass: 59.180 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
FERM_M 1. 25139107.25.7e-29
FERM_C 1. 143232177.63.5e-50
--- cleavage 215 (inside FERM_C 143..232) ---
--- cleavage 211 (inside FERM_C 143..232) ---
ERM 1. 264497294.22.8e-85

3. Sequence Information

Fasta Sequence: XSB0752.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] KLRVNKLILQ215-LCIGNHDLFM

Gln215 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys206Leu207Arg208Val209Asn210Lys211Leu212Ile213Leu214Gln215
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu216Cys217Ile218Gly219Asn220His221Asp222Leu223Phe224Met225

Sequence conservation (by blast)

[Site 2] FNSSKLRVNK211-LILQLCIGNH

Lys211 Leu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe202Asn203Ser204Ser205Lys206Leu207Arg208Val209Asn210Lys211
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Leu212Ile213Leu214Gln215Leu216Cys217Ile218Gly219Asn220His221

Sequence conservation (by blast)

* References

None.