XSB0806 : unnamed protein product [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0001
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Putative uncharacterized protein |
| Gene Names | Capn2 |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 700 aa
Average Mass: 79.800 kDa
Monoisotopic Mass: 79.750 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 19 --- | ||||
| Peptidase_C2 1. | 45 | 344 | 810.8 | 8.5e-241 |
| Calpain_III 1. | 355 | 510 | 381.5 | 1.5e-111 |
| efhand 1. | 576 | 604 | 20.4 | 0.0074 |
| efhand 2. | 606 | 634 | 19.4 | 0.015 |
| efhand 3. | 671 | 698 | 1.8 | 13 |
3. Sequence Information
Fasta Sequence: XSB0806.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] KDREAAEGLG19-SHERAIKYLN
Gly19 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys10 | Asp11 | Arg12 | Glu13 | Ala14 | Ala15 | Glu16 | Gly17 | Leu18 | Gly19 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser20 | His21 | Glu22 | Arg23 | Ala24 | Ile25 | Lys26 | Tyr27 | Leu28 | Asn29 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MAGIAIKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDP |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 100.00 | 20 | unnamed protein product |
| 2 | N/A | 100.00 | 14 | C |
| 3 | Rattus norvegicus | 99.80 | 9 | calpain 2 |
| 4 | Homo sapiens | 95.50 | 25 | calpain 2, large subunit |
| 5 | catalytic | 95.50 | 1 | Calpain 2, large |
| 6 | Macaca mulatta | 94.00 | 3 | PREDICTED: calpain 2, large subunit |
| 7 | Bos taurus | 92.40 | 7 | Unknown (protein for MGC:138930) |
| 8 | Monodelphis domestica | 80.10 | 2 | PREDICTED: similar to calpain 2 |
| 9 | Xenopus laevis | 69.70 | 10 | hypothetical protein LOC399075 |
| 10 | Gallus gallus | 68.90 | 5 | calpain 1, (mu/I) large subunit |
| 11 | Coturnix coturnix | 68.20 | 1 | quail calpain |
| 12 | Xenopus tropicalis | 67.80 | 6 | calpain 2, (m/II) large subunit |
| 13 | Canis familiaris | 67.40 | 6 | PREDICTED: similar to calpain 8 |
| 14 | Danio rerio | 64.30 | 31 | hypothetical protein LOC550505 |
| 15 | Tetraodon nigroviridis | 60.10 | 7 | unnamed protein product |
| 16 | Oncorhynchus mykiss | 60.10 | 3 | m-calpain |
| 17 | Pan troglodytes | 59.70 | 6 | PREDICTED: similar to calpain, partial |
| 18 | Stizostedion vitreum vitreum | 59.70 | 1 | putative calpain-like protein |
| 19 | Pongo pygmaeus | 55.80 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 20 | synthetic construct | 55.80 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 21 | Sus scrofa | 55.10 | 3 | micromolar calcium-activated neutral protease 1 is |
| 22 | Macaca fascicularis | 40.80 | 1 | unnamed protein product |
| 23 | Bos grunniens | 35.40 | 1 | micromolar calcium-activated neutral protease 1 la |
| 24 | Drosophila melanogaster | 35.00 | 6 | CAA55297.1 |
| 25 | Aedes aegypti | 35.00 | 1 | calpain, putative |
| 26 | Oryctolagus cuniculus | 34.70 | 1 | calpain 3, (p94) |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| N/A | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| Rattus norvegicus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||+|||||||||||||#|||||||||||||||||||||||||||||| Sbjct 1 MAGIAMKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| Homo sapiens | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 1 MAGIAAKLAKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 49 |
| catalytic | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 30 MAGIAAKLAKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 78 |
| Macaca mulatta | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| || ||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 1 MAGIAAKLVKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 49 |
| Bos taurus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||+||||||| ||+|||||||||||| Sbjct 1 MAGIAAKLAKDREAAEGLG#SHERAVKYLNQDYAALRDECLEAGALFQDP 49 |
| Monodelphis domestica | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+||| |+ +||||| |||#+||+|+|||||||||| +|||| | ||||| Sbjct 1 MSGIAAKVVRDREAAAGLG#THEQAVKYLNQDYETLLSECLEEGKLFQDP 49 |
| Xenopus laevis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+|+| +|||+| | | |#++|+|+ |||||+| ||||||++|+||+|| Sbjct 1 MSGVADRLAKERARASGFG#TNEKALPYLNQDFEALRNECLQSGSLFKDP 49 |
| Gallus gallus | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||| +| +|| |||+|# | |+|||||||| |+ ||+|+| ||+|| Sbjct 6 GIAARLQRDRLRAEGVG#EHNNAVKYLNQDYEALKQECIESGTLFRDP 52 |
| Coturnix coturnix | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||| +| +|| |||+|# | |+|||||||| |+ |+|+||||+|| Sbjct 6 GIAARLQRDRLRAEGVG#EHNNAVKYLNQDYEALKQACIESGALFRDP 52 |
| Xenopus tropicalis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+|+| +|||+| | |||#++|+|+ ||+|||| ||||||++| ||+| Sbjct 1 MSGVADRLAKERALASGLG#TNEKALPYLSQDYEALRNECLQSGTLFKD 48 |
| Canis familiaris | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+ +| ++|| + || |||#||++|+||| ||+| || +||+|| ||+|| Sbjct 94 MSALAARIAKQQAAAGGLG#SHQKAVKYLGQDFEKLRQQCLDAGVLFKDP 142 |
| Danio rerio | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| || |+| | |+|#++ +| |+|||||| |+ ||||+| |||| Sbjct 1 MSGIATKLQKNRARAAGIG#TNAQAAKFLNQDYEALKRECLESGRLFQD 48 |
| Tetraodon nigroviridis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| || |+ |+| |#+ +| ||||||+|+|| ||| | |||| Sbjct 1 MSGIAAKLQHHRDRAQGFG#TASQAQKYLNQDFESLRESCLERGELFQD 48 |
| Oncorhynchus mykiss | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+|+| ||| | | | |#++ |+||||||+| || +|| | || || Sbjct 1 MSGMASNLAKKRALAAGFG#TNANAVKYLNQDFEALRAQCLNRGGLFSDP 49 |
| Pan troglodytes | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 || | +++ | | +|||#|++ |+||| ||++||| +||++| ||+|| Sbjct 1 MAAQAAGVSRQRAATQGLG#SNQNALKYLGQDFKTLRQQCLDSGVLFKDP 49 |
| Stizostedion vitreum vitreum | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| | + || +|+|#| +|+|||||||| || |||+ +||+| Sbjct 1 MSGIAATLQRRREKEQGIG#SCSQAVKYLNQDYEALRRRCLESESLFKD 48 |
| Pongo pygmaeus | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++| ||+| Sbjct 13 GVSAQVQKQRARELGLG#RHENAIKYLGQDYEQLRVRCLQSGTLFRD 58 |
| synthetic construct | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++| ||+| Sbjct 13 GVSAQVQKQRARELGLG#RHENAIKYLGQDYEQLRVRCLQSGTLFRD 58 |
| Sus scrofa | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++|+||+| Sbjct 13 GVSAQVQKLRAKELGLG#RHENAIKYLGQDYEQLRAHCLQSGSLFRD 58 |
| Macaca fascicularis | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+ + | | |+|# | | + || +| || || | ||+|| Sbjct 36 GMVAHINYSRLKASGVG#QHHNAHNFGNQSFEELRAVCLRKGELFEDP 82 |
| Bos grunniens | Query 27 YLNQDYETLRNECLEAGALFQD 48 || |||| || ||+ ||||+| Sbjct 1 YLGQDYEQLRVHCLQRGALFRD 22 |
| Drosophila melanogaster | Query 30 QDYETLRNECLEAGALFQDP 49 |||||+ | || +|+||+|| Sbjct 50 QDYETILNSCLASGSLFEDP 69 |
| Aedes aegypti | Query 30 QDYETLRNECLEAGALFQDP 49 ||| ||++|||+|+||+|| Sbjct 115 QDYYVLRSQCLESGSLFEDP 134 |
| Oryctolagus cuniculus | Query 7 KLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 ++ ++|+ | |#+ + ||| ||+ || || ||+| Sbjct 12 RVIRERDRRNGEG#TVTQPIKYEGQDFVVLRQRCLAQKCLFED 53 |
* References
[PubMed ID: 10349636] Carninci P, Hayashizaki Y, High-efficiency full-length cDNA cloning. Methods Enzymol. 1999;303:19-44.
[PubMed ID: 11042159] ... Carninci P, Shibata Y, Hayatsu N, Sugahara Y, Shibata K, Itoh M, Konno H, Okazaki Y, Muramatsu M, Hayashizaki Y, Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Genome Res. 2000 Oct;10(10):1617-30.
[PubMed ID: 11076861] ... Shibata K, Itoh M, Aizawa K, Nagaoka S, Sasaki N, Carninci P, Konno H, Akiyama J, Nishi K, Kitsunai T, Tashiro H, Itoh M, Sumi N, Ishii Y, Nakamura S, Hazama M, Nishine T, Harada A, Yamamoto R, Matsumoto H, Sakaguchi S, Ikegami T, Kashiwagi K, Fujiwake S, Inoue K, Togawa Y, RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Genome Res. 2000 Nov;10(11):1757-71.
[PubMed ID: 11217851] ... Kawai J, Shinagawa A, Shibata K, Yoshino M, Itoh M, Ishii Y, Arakawa T, Hara A, Fukunishi Y, Konno H, Adachi J, Fukuda S, Aizawa K, Izawa M, Nishi K, Kiyosawa H, Kondo S, Yamanaka I, Saito T, Okazaki Y, Gojobori T, Bono H, Kasukawa T, Saito R, Kadota K, Matsuda H, Ashburner M, Batalov S, Casavant T, Fleischmann W, Gaasterland T, Gissi C, King B, Kochiwa H, Kuehl P, Lewis S, Matsuo Y, Nikaido I, Pesole G, Quackenbush J, Schriml LM, Staubli F, Suzuki R, Tomita M, Wagner L, Washio T, Sakai K, Okido T, Furuno M, Aono H, Baldarelli R, Barsh G, Blake J, Boffelli D, Bojunga N, Carninci P, de Bonaldo MF, Brownstein MJ, Bult C, Fletcher C, Fujita M, Gariboldi M, Gustincich S, Hill D, Hofmann M, Hume DA, Kamiya M, Lee NH, Lyons P, Marchionni L, Mashima J, Mazzarelli J, Mombaerts P, Nordone P, Ring B, Ringwald M, Rodriguez I, Sakamoto N, Sasaki H, Sato K, Schonbach C, Seya T, Shibata Y, Storch KF, Suzuki H, Toyo-oka K, Wang KH, Weitz C, Whittaker C, Wilming L, Wynshaw-Boris A, Yoshida K, Hasegawa Y, Kawaji H, Kohtsuki S, Hayashizaki Y, Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90.
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[PubMed ID: 16141072] ... Carninci P, Kasukawa T, Katayama S, Gough J, Frith MC, Maeda N, Oyama R, Ravasi T, Lenhard B, Wells C, Kodzius R, Shimokawa K, Bajic VB, Brenner SE, Batalov S, Forrest AR, Zavolan M, Davis MJ, Wilming LG, Aidinis V, Allen JE, Ambesi-Impiombato A, Apweiler R, Aturaliya RN, Bailey TL, Bansal M, Baxter L, Beisel KW, Bersano T, Bono H, Chalk AM, Chiu KP, Choudhary V, Christoffels A, Clutterbuck DR, Crowe ML, Dalla E, Dalrymple BP, de Bono B, Della Gatta G, di Bernardo D, Down T, Engstrom P, Fagiolini M, Faulkner G, Fletcher CF, Fukushima T, Furuno M, Futaki S, Gariboldi M, Georgii-Hemming P, Gingeras TR, Gojobori T, Green RE, Gustincich S, Harbers M, Hayashi Y, Hensch TK, Hirokawa N, Hill D, Huminiecki L, Iacono M, Ikeo K, Iwama A, Ishikawa T, Jakt M, Kanapin A, Katoh M, Kawasawa Y, Kelso J, Kitamura H, Kitano H, Kollias G, Krishnan SP, Kruger A, Kummerfeld SK, Kurochkin IV, Lareau LF, Lazarevic D, Lipovich L, Liu J, Liuni S, McWilliam S, Madan Babu M, Madera M, Marchionni L, Matsuda H, Matsuzawa S, Miki H, Mignone F, Miyake S, Morris K, Mottagui-Tabar S, Mulder N, Nakano N, Nakauchi H, Ng P, Nilsson R, Nishiguchi S, Nishikawa S, Nori F, Ohara O, Okazaki Y, Orlando V, Pang KC, Pavan WJ, Pavesi G, Pesole G, Petrovsky N, Piazza S, Reed J, Reid JF, Ring BZ, Ringwald M, Rost B, Ruan Y, Salzberg SL, Sandelin A, Schneider C, Schonbach C, Sekiguchi K, Semple CA, Seno S, Sessa L, Sheng Y, Shibata Y, Shimada H, Shimada K, Silva D, Sinclair B, Sperling S, Stupka E, Sugiura K, Sultana R, Takenaka Y, Taki K, Tammoja K, Tan SL, Tang S, Taylor MS, Tegner J, Teichmann SA, Ueda HR, van Nimwegen E, Verardo R, Wei CL, Yagi K, Yamanishi H, Zabarovsky E, Zhu S, Zimmer A, Hide W, Bult C, Grimmond SM, Teasdale RD, Liu ET, Brusic V, Quackenbush J, Wahlestedt C, Mattick JS, Hume DA, Kai C, Sasaki D, Tomaru Y, Fukuda S, Kanamori-Katayama M, Suzuki M, Aoki J, Arakawa T, Iida J, Imamura K, Itoh M, Kato T, Kawaji H, Kawagashira N, Kawashima T, Kojima M, Kondo S, Konno H, Nakano K, Ninomiya N, Nishio T, Okada M, Plessy C, Shibata K, Shiraki T, Suzuki S, Tagami M, Waki K, Watahiki A, Okamura-Oho Y, Suzuki H, Kawai J, Hayashizaki Y, The transcriptional landscape of the mammalian genome. Science. 2005 Sep 2;309(5740):1559-63.
[PubMed ID: 16141073] ... Katayama S, Tomaru Y, Kasukawa T, Waki K, Nakanishi M, Nakamura M, Nishida H, Yap CC, Suzuki M, Kawai J, Suzuki H, Carninci P, Hayashizaki Y, Wells C, Frith M, Ravasi T, Pang KC, Hallinan J, Mattick J, Hume DA, Lipovich L, Batalov S, Engstrom PG, Mizuno Y, Faghihi MA, Sandelin A, Chalk AM, Mottagui-Tabar S, Liang Z, Lenhard B, Wahlestedt C, Antisense transcription in the mammalian transcriptome. Science. 2005 Sep 2;309(5740):1564-6.