logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB0943 : PREDICTED: similar to integrin beta chain, beta 3 precursor isoform 2 [Macaca mulatta]

[ CaMP Format ]

This entry is computationally expanded from SB0043

* Basic Information

OrganismMacaca mulatta (rhesus monkey)
Protein Namessimilar to integrin beta chain; beta 3 precursor isoform 2
Gene NamesLOC717379; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 5 mRNAs, 61 ESTs, 11 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_001116013 XM_001116013 717379 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 788 aa

Average Mass: 86.961 kDa

Monoisotopic Mass: 86.903 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
DUF2474 1. 725-21.98.3
Integrin_beta 1. 384611050.20
EGF_2 1. 46349713.20.09
EGF_2 2. 51254732.02.4e-06
EGF_2 3. 55458422.80.0014
EGF_2 4. 59362430.28.2e-06
Integrin_B_tail 1. 634718128.03e-35
Integrin_b_cyt 1. 742787106.87.1e-29
--- cleavage 761 (inside Integrin_b_cyt 742..787) ---
--- cleavage 767 (inside Integrin_b_cyt 742..787) ---
--- cleavage 785 (inside Integrin_b_cyt 742..787) ---
--- cleavage 773 (inside Integrin_b_cyt 742..787) ---

3. Sequence Information

Fasta Sequence: XSB0943.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] EFAKFEEERA761-RAKWDTANNP

Ala761 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu752Phe753Ala754Lys755Phe756Glu757Glu758Glu759Arg760Ala761
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg762Ala763Lys764Trp765Asp766Thr767Ala768Asn769Asn770Pro771

Sequence conservation (by blast)

[Site 2] EERARAKWDT767-ANNPLYKEAT

Thr767 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu758Glu759Arg760Ala761Arg762Ala763Lys764Trp765Asp766Thr767
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala768Asn769Asn770Pro771Leu772Tyr773Lys774Glu775Ala776Thr777

Sequence conservation (by blast)

[Site 3] ATSTFTNITY785-RGT

Tyr785 Arg

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ala776Thr777Ser778Thr779Phe780Thr781Asn782Ile783Thr784Tyr785
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Arg786Gly787Thr788-------

Sequence conservation (by blast)

[Site 4] KWDTANNPLY773-KEATSTFTNI

Tyr773 Lys

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys764Trp765Asp766Thr767Ala768Asn769Asn770Pro771Leu772Tyr773
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Lys774Glu775Ala776Thr777Ser778Thr779Phe780Thr781Asn782Ile783

Sequence conservation (by blast)

* References

None.