CaMPDB :: Substrate

XSB0961 : integrin beta 2 [Mus musculus]

This entry is computationally expanded from SB0002

* Basic Information

Organism	Mus musculus (house mouse)
Protein Names	Integrin beta-2; Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta; Complement receptor C3 subunit beta; integrin beta 2; Mac-1 beta; macrophage antigen-1 beta; lymphocyte function associated antigen 1
Gene Names	Itgb2; integrin beta 2
Gene Locus	10 41.5 cM; chromosome 10
GO Function	Not available

Entrez Protein	Entrez Nucleotide	Entrez Gene	UniProt	OMIM	HGNC	HPRD	KEGG
NP_032430	NM_008404	16414	P11835	N/A	N/A	N/A	mmu:16414

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 770 aa

Average Mass: 84.894 kDa

Monoisotopic Mass: 84.838 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain name	begin	end	score	e-value
Integrin_beta 1.	32	447	1064.1	0
EGF_2 1.	449	481	20.8	0.0058
EGF_2 2.	497	534	16.1	0.041
EGF_2 3.	541	573	27.1	7e-05
EGF_2 4.	582	612	26.5	0.00011
Integrin_B_tail 1.	622	701	121.7	2.4e-33
Integrin_b_cyt 1.	725	769	85.5	1.9e-22
--- cleavage 745 (inside Integrin_b_cyt 725..769) ---
--- cleavage 763 (inside Integrin_b_cyt 725..769) ---
--- cleavage 761 (inside Integrin_b_cyt 725..769) ---
--- cleavage 755 (inside Integrin_b_cyt 725..769) ---

3. Sequence Information

Fasta Sequence: XSB0961.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] YRRFEKEKLK⁷⁴⁵-SQWNNDNPLF

Lys⁷⁴⁵ Ser

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Tyr⁷³⁶	Arg⁷³⁷	Arg⁷³⁸	Phe⁷³⁹	Glu⁷⁴⁰	Lys⁷⁴¹	Glu⁷⁴²	Lys⁷⁴³	Leu⁷⁴⁴	Lys⁷⁴⁵

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Ser⁷⁴⁶	Gln⁷⁴⁷	Trp⁷⁴⁸	Asn⁷⁴⁹	Asn⁷⁵⁰	Asp⁷⁵¹	Asn⁷⁵²	Pro⁷⁵³	Leu⁷⁵⁴	Phe⁷⁵⁵

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
IGVLLLVIWKALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES

Summary

#	organism	max score	hits	top seq
1	N/A	115.00	29	I
2	Mus musculus	115.00	16	integrin beta 2
3	Rattus norvegicus	113.00	10	PREDICTED: similar to Integrin beta-2 precursor (C
4	Sigmodon hispidus	113.00	1	AF445415_1 integrin beta-2 precursor
5	Homo sapiens	110.00	25	leukocyte adhesion protein beta-subunit precursor
6	Pan troglodytes	110.00	14	integrin, beta 2
7	Bos taurus	110.00	13	integrin, beta 2
8	synthetic construct	110.00	5	integrin, beta 2 (antigen CD18 (p95), lymphocyte f
9	Bubalus bubalis	110.00	1	integrin beta-2
10	Capra hircus	110.00	1	ITB2_CAPHI Integrin beta-2 precursor (Cell surface
11	Ovis aries	109.00	2	antigen CD18
12	Ovis canadensis	109.00	1	ITB2_OVICA Integrin beta-2 precursor (Cell surface
13	Sus scrofa	107.00	6	CD18 leukocyte adhesion molecule
14	Canis familiaris	106.00	10	AF181965_1 B-2 integrin
15	Monodelphis domestica	89.40	6	PREDICTED: similar to Stromal interaction molecule
16	Gallus gallus	80.90	7	integrin, beta 2
17	Xenopus laevis	67.00	6	hypothetical protein LOC379708
18	Felis catus	64.70	1	integrin beta 1
19	Danio rerio	64.30	14	integrin, beta 1b
20	Tetraodon nigroviridis	64.30	8	unnamed protein product
21	Oryctolagus cuniculus	64.30	2	integrin beta 1
22	Pongo pygmaeus	64.30	2	ITB1_PONPY Integrin beta-1 precursor (Fibronectin
23	Xenopus tropicalis	64.30	1	integrin beta 1 (fibronectin receptor beta)
24	Pacifastacus leniusculus	63.90	1	integrin
25	Ictalurus punctatus	63.50	2	beta-1 integrin
26	Oncorhynchus mykiss	63.50	1	CD18 protein
27	Anopheles gambiae str. PEST	62.40	1	ENSANGP00000021373
28	Anopheles gambiae	62.40	1	integrin beta subunit
29	Caenorhabditis briggsae	62.00	1	Hypothetical protein CBG03601
30	Aedes aegypti	61.60	1	integrin beta subunit
31	Cyprinus carpio	60.80	2	CD18 type 2
32	Caenorhabditis elegans	60.80	1	Paralysed Arrest at Two-fold family member (pat-3)
33	Drosophila melanogaster	60.50	1	myospheroid CG1560-PA
34	Ostrinia furnacalis	59.70	1	integrin beta 1 precursor
35	Crassostrea gigas	59.30	1	integrin beta cgh
36	Tribolium castaneum	58.90	3	PREDICTED: similar to CG1560-PA
37	Biomphalaria glabrata	58.20	1	beta integrin subunit
38	Apis mellifera	57.40	1	PREDICTED: similar to myospheroid CG1560-PA
39	Pseudoplusia includens	57.40	1	integrin beta 1
40	Strongylocentrotus purpuratus	55.80	6	PREDICTED: similar to integrin beta L subunit, par
41	Podocoryne carnea	55.50	1	AF308652_1 integrin beta chain
42	Mus sp.	55.10	1	beta 7 integrin
43	Macaca mulatta	54.70	13	PREDICTED: integrin, beta 7
44	Lytechinus variegatus	53.90	1	beta-C integrin subunit
45	Acropora millepora	52.00	1	integrin subunit betaCn1
46	Canis lupus familiaris	49.30	1	integrin beta chain, beta 3
47	rats, Peptide Partial, 723 aa	49.30	1	beta 3 integrin, GPIIIA
48	mice, Peptide Partial, 680 aa	49.30	1	beta 3 integrin, GPIIIA
49	Equus caballus	49.30	1	integrin, beta 3 (platelet glycoprotein IIIa, anti
50	Halocynthia roretzi	48.50	2	integrin beta Hr2 precursor
51	Schistosoma japonicum	45.80	1	SJCHGC06221 protein
52	Ophlitaspongia tenuis	44.70	1	integrin subunit betaPo1
53	Geodia cydonium	43.10	1	integrin beta subunit
54	Spodoptera frugiperda	42.00	1	integrin beta 1
55	Suberites domuncula	39.70	1	integrin beta subunit
56	Manduca sexta	39.70	1	plasmatocyte-specific integrin beta 1
57	Drosophila pseudoobscura	33.90	1	GA14581-PA

Top-ranked sequences

organism	matching
N/A	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770
Mus musculus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770
Rattus norvegicus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 714 IGVLLLVIWKALTHLTDLNEYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 768
Sigmodon hispidus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 IGVLLLVIWKALTHLTDLREYRHFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
Homo sapiens	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|+\|\|\|\|\|\|\|\|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 IGILLLVIWKALIHLSDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
Pan troglodytes	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|+\|\|\|\|\|\|\|\|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 IGILLLVIWKALIHLSDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
Bos taurus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 +\|+\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 VGILLLVIWKALTHLSDLREYHRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
synthetic construct	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|+\|\|\|\|\|\|\|\|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 IGILLLVIWKALIHLSDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
Bubalus bubalis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 +\|+\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 VGILLLVIWKALTHLSDLREYHRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 769
Capra hircus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 +\|+\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 716 VGILLLVIWKALTHLSDLREYHRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770
Ovis aries	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 +\|+\|\|\| \|\|\|\|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 716 VGILLLAIWKALTHLSDLREYHRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770
Ovis canadensis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 +\|+\|\|\| \|\|\|\|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 716 VGILLLAIWKALTHLSDLREYHRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770
Sus scrofa	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAE 769 +\|+ \|\|\|\|\|\| \|\|\|\|+\|\|\|\|\|+\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 715 VGIFLLVIWKVLTHLSDLREYKRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAE 768
Canis familiaris	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|+\|\|\| \|\|\|\|\|\|\|\|+\|\|\|\|++\|\|\|\|\|\|\|+#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\|\|\|\| Sbjct 710 IGILLLAIWKALTHLSDLREFKRFEKEKLR#SQWNNDNPLFKSATTTVMNPRFAES 764
Monodelphis domestica	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNP 765 \|\|\|\|\|\| +\|\| \|\|\| +\|\|\|\|\|+\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\| \|\|\|++ \| Sbjct 1181 IGVLLLAVWKVLTHFSDLREYKRFEKEKLK#SQWNNDNPLFKKKTTTIIIP 1230
Gallus gallus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMNPKF 767 \|\|+\|\|\|+ \|+ \|\| + \| \|\|\|\|\|\|\|\|\|\| \|#++\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|+\| Sbjct 717 IGLLLLLTWRLLTEIFDRREYRRFEKEKSK#AKWNEADNPLFKSATTTVMNPRF 769
Xenopus laevis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 \|\|+ \|+\|\|\| +\| + \| \|\|+\|\|\|\|\|++ #\|+\|\| \|\|\|+ +\|\|\|\|\| \|\| \|+ Sbjct 717 IGLACLIIWKIITEIKDRNEYQRFEKERMN#SKWNPGHNPLYHNATTTVQNPNFS 770
Felis catus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 743 IGLALLLIWKLLMIIHDTREFAKFEKEKMN#AKWDTGENPIYKSAVTTVVNPKY 795
Danio rerio	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 740 IGLALLLIWKLLMIIHDRREFAKFEKEKMN#AKWDAGENPIYKSAVTTVVNPKY 792
Tetraodon nigroviridis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 736 IGLALLLIWKLLMIIHDRREFAKFEKEKMN#AKWDTGENPIYKSAVTTVVNPKY 788
Oryctolagus cuniculus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 8 IGLALLLIWKLLMIIHDRREFAKFEKEKMN#AKWDTGENPIYKSAVTTVVNPKY 60
Pongo pygmaeus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 743 IGLALLLIWKLLMIIHDRREFAKFEKEKMN#AKWDTGENPIYKSAVTTVVNPKY 795
Xenopus tropicalis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 743 IGLALLLIWKLLMIIHDRREFAKFEKEKMN#AKWDTGENPIYKSAVTTVVNPKY 795
Pacifastacus leniusculus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKE-KLK#SQWNNDNPLFKSATTTVMNPKFAES 770 \|\|+\| \|+\|\|\| \|\| \| \| \|\|\| +\|\|\|\| \|\| #\| +\|\|\|+\|\|\| \|\| \|\| \|\|+\| Sbjct 745 IGLLTLLIWKLLTTLHDRREYAKFEKERKLP#SGKRAENPLYKSAKTTFQNPAFAQS 800
Ictalurus punctatus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+ \|\| \|\|\| \| + \| \|\|+ +\|\|\|\|\|+ #++\|+ +\|\|++\|\|\| \|\|\|+\|\|\|+ Sbjct 752 IGLALLFIWKLLMIIHDRREFAKFEKEKMN#AKWDAGENPIYKSAVTTVVNPKY 804
Oncorhynchus mykiss	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+\|+\|+\| \|\|+ ++ \|++\|+\|\|\|\| \|+ \|# +\|+ \|\|\|\|\| +\|\|\|\|\| \|\| \| Sbjct 722 IGLLILLIIKAILYMRDVKEFRRFENEQKK#GKWSPGDNPLFMNATTTVANPTF 774
Anopheles gambiae str. PEST	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 \|\|+ +\|++\|\| \|\| + \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|\|\| \|\| +\| Sbjct 782 IGMAVLLLWKVLTSIHDRREFARFEKERMM#AKWDTGENPIYKQATTTFKNPTYA 835
Anopheles gambiae	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 \|\|+ +\|++\|\| \|\| + \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|\|\| \|\| +\| Sbjct 782 IGMAVLLLWKVLTSIHDRREFARFEKERMM#AKWDTGENPIYKQATTTFKNPTYA 835
Caenorhabditis briggsae	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 +\|+\|\|\|++\|\| \|\| \| \| \|\| +\| \|+\| #++\|+ \|+\|\|++\| \|\|\|\| \|\| +\| Sbjct 753 LGILLLLLWKLLTVLHDRAEYAKFNNERLM#AKWDTNENPIYKQATTTFKNPVYA 806
Aedes aegypti	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 \|\|+ +\|++\|\| \|\| + \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|\|\| \|\| +\| Sbjct 780 IGLAVLLLWKLLTTIHDRREFARFEKERMM#AKWDTGENPIYKQATTTFKNPTYA 833
Cyprinus carpio	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPKFA 768 \|\|+\|+\|+\| \|\|+ + +\|\|\|\|++\|\|\|\|++ # + + \|\|\|\|++\|\|\|\|\| \|\| \|+ Sbjct 712 IGLLILLIIKAVLYASDLREWKRFEKDRKH#EKTSGTNPLFQNATTTVQNPTFS 764
Caenorhabditis elegans	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 +\|+\|\|\|++\|\| \|\| \| \| \|\| \| \|+\| #++\|+ \|+\|\|++\| \|\|\|\| \|\| +\| Sbjct 752 LGILLLLLWKLLTVLHDRSEYATFNNERLM#AKWDTNENPIYKQATTTFKNPVYA 805
Drosophila melanogaster	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 +\|+ +\|++\|\| \|\| + \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|+\| \|\| +\| Sbjct 791 VGLAILLLWKLLTTIHDRREFARFEKERMN#AKWDTGENPIYKQATSTFKNPMYA 844
Ostrinia furnacalis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 +\|+ \|\|++\|\| +\| + \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|+\| \|\| +\| Sbjct 776 VGLALLMLWKMVTTIHDRREFARFEKERMM#AKWDTGENPIYKQATSTFKNPTYA 829
Crassostrea gigas	Query 717 GVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFAE 769 \|++\|\|+\|\|\| \| ++\| \|\| \|\|\|\|\| + #++\|+ +\|\|++\| \|\|+\| +\|\| + + Sbjct 746 GIILLLIWKLFTTISDKRELARFEKEAMN#ARWDTGENPIYKQATSTFVNPTYRQ 799
Tribolium castaneum	Query 717 GVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+\|\|+ \|\| \| + \| +\|\| +\|\| \|+ \|# \|\|+ \|\|\|\|\|++ \|\|+\| \|\| + Sbjct 700 GVILLLTWKVCTTVHDRQEYAKFENERQK#MQWHRNDNPLYRQATSTFKNPVY 751
Biomphalaria glabrata	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 +\|+ \|\|++\|\| \|\| + \| \|\|+ +\|\|\|\|+ #++\|+ +\|\|++\| \|\|+\| \|\| + Sbjct 733 VGLFLLLLWKLLTFIHDTREFAKFEKERQN#AKWDTGENPIYKQATSTFKNPTY 785
Apis mellifera	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEK-LK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\| +\|+ \|\| \|\| + \| \|\|+++\|\|+\|+ \| #++\|\| \|\|\|\|+\| \|\|+\| \|\| \| Sbjct 760 IGFAILLTWKILTMIRDNREFKKFERERILA#NKWNRRDNPLYKEATSTFKNPTF 813
Pseudoplusia includens	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFA 768 +\|+ \|\|++\|\| \| \| \|\|+ \|\|\|\|\|++ #++\|+ +\|\|++\| \|\|+\| \|\| +\| Sbjct 782 VGLALLMLWKMATTSHDRREFARFEKERMM#AKWDTGENPIYKQATSTFKNPTYA 835
Strongylocentrotus purpuratus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKFAE 769 \|\|++\|+ \|+ \|++ \| \|\|\| ++\| + \|#+\|\|+ +\|\|\|++\|\|+\|\|\| \|\| + + Sbjct 94 IGMILVCAWRLYTYVQDKREYAQWENDCKK#AQWDQSDNPIYKSSTTTFKNPTYGK 148
Podocoryne carnea	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMNPKF 767 \|\|+ \|\|+\|\|\| \| + \| \|\|+ +\|\|\|++ # +\|++ +\|\|++\| \|\|+\| \|\| + Sbjct 726 IGLALLLIWKLLATIQDRREFAKFEKDRQN#PKWDSGENPIYKKATSTFQNPMY 778
Mus sp.	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNND-NPLFKSATTTVMNPKF 767 +\|+ \|++ ++ + \| \|\|\|\|\|\|\|\|\|+ +# \| \| \|\|\|+\|\|\| \|\| +\|\|+\| Sbjct 737 VGLGLVLAYRLSVEIYDRREYRRFEKEQQQ#LNWKQDNNPLYKSAITTTVNPRF 789
Macaca mulatta	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNND-NPLFKSATTTVMNPKFAES 770 +\|+ \|++ ++ + \| \|\|\| \|\|\|\|\|+ +# \| \| \|\|\|+\|\|\| \|\| +\|\|+\| \|+ Sbjct 614 VGLGLVLAYRLSVEIYDRREYSRFEKEQQQ#LNWKQDSNPLYKSAITTTINPRFQEA 669
Lytechinus variegatus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQW-NNDNPLFKSATTTVMNPKF 767 +\|+ \|\|+\|\|+ \|\|++ \| \|\|++ \|\|\|\|+ #+ \| +\|\|++\| +\|+ \|\| + Sbjct 751 VGLALLLIWRLLTYIHDRREFQNFEKERAN#ATWEGGENPIYKPSTSVFKNPTY 803
Acropora millepora	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNND-NPLFKSATTTVMNPKFA 768 +\|+\|+\|++ \| \| + \| \|\|++\|\|+\|++ #\|+\| + \|\|\|+++\| \|\| \|\| +\| Sbjct 735 LGLLILIVIKGLFTMVDRIEYQKFERERMH#SKWTREKNPLYQAAKTTFENPTYA 788
Canis lupus familiaris	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMN 764 \|\|+ \|+\|\|\| \| + \| +\|+ +\|\|+\|+ +#++\|+ +\|\|\|+\| \|\|+\| \| Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEERAR#AKWDTANNPLYKEATSTFTN 778
rats, Peptide Partial, 723 aa	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMN 764 \|\|+ \|+\|\|\| \| + \| +\|+ +\|\|+\|+ +#++\|+ +\|\|\|+\| \|\|+\| \| Sbjct 668 IGLATLLIWKLLITIHDRKEFAKFEEERAR#AKWDTANNPLYKEATSTFTN 717
mice, Peptide Partial, 680 aa	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMN 764 \|\|+ \|+\|\|\| \| + \| +\|+ +\|\|+\|+ +#++\|+ +\|\|\|+\| \|\|+\| \| Sbjct 629 IGLATLLIWKLLITIHDRKEFAKFEEERAR#AKWDTANNPLYKEATSTFTN 678
Equus caballus	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMN 764 \|\|+ \|+\|\|\| \| + \| +\|+ +\|\|+\|+ +#++\|+ +\|\|\|+\| \|\|+\| \| Sbjct 729 IGLATLLIWKLLITIHDRKEFAKFEEERAR#AKWDTANNPLYKEATSTFTN 778
Halocynthia roretzi	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQW-NNDNPLFKSATTTVMNPKF 767 \|\|++ \|+\|\|\| + \| \| \|\|\| +\|+\|\|+ # +\| +\|\|++ +\|++ \|\| \| Sbjct 779 IGIIALIIWKVIQTLRDKREYEKFKKEEDL#RKWTKGENPVYVNASSKFDNPMF 831
Schistosoma japonicum	Query 717 GVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNN-DNPLFKSATTTVMNPKFAES 770 \|++\|\|+\|+\| + + \| \|\| \|+++ # +\| +\|\|+\|+\| \|\| \|+\|\| \| \|+ Sbjct 232 GLILLLIYKLVITIDDRRELANFKQQGEN#MRWEMAENPIFESPTTNVLNPTFEEN 286
Ophlitaspongia tenuis	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQW-NNDNPLFKSATTTVMNPKFAE 769 +\|+\|\|\|++ \| \| \| \|+ \| \|+\|\|+\| #+++ \|+\|\|\|++\|\|\| \|\| + + Sbjct 784 LGLLLLLLLKGLLLLWDVVEVRKFEREIKN#AKYTKNENPLYRSATKDYQNPLYGK 838
Geodia cydonium	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQW-NNDNPLFKSATTTVMNPKFAE 769 +\|+\| \|++ \| \| + \| \| ++\|\| \| \|# ++ \|+\|\|\|+ \|\|\|\| \|\| + + Sbjct 824 LGILALILLKILLMVLDYTELKKFENELAK#VKYTKNENPLYHSATTEHKNPIYGQ 878
Spodoptera frugiperda	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+\| ++\|\|\| \| + \| +\|\|++\|+ \| \| #+ ++ + \|\|\|++ + \|\| + Sbjct 724 IGILTVIIWKILVDMHDKKEYKKFQDEALA#AGYDVSLNPLYQDPSINFSNPVY 776
Suberites domuncula	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQW-NNDNPLFKSATTTVMNPKFAE 769 +\|\|+ \|++ \| + \|+ \| ++\|\|\|\| \|#+++ + \|\|\|++\|\| \|\| + + Sbjct 710 LGVIALLLLKLFLFIIDVIEVKKFEKELAK#TKYPKHQNPLYRSAAKDYQNPIYGQ 764
Manduca sexta	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWN-NDNPLFKSATTTVMNPKF 767 \|\|+\| \|+ \|\| \| \| \| \|\|\| +\|\|+\| # ++ + \|\|\|++ \|\| + Sbjct 709 IGLLTLIAWKILVDLHDKREYAKFEEESRS#RGFDVSLNPLYQEPEINFSNPVY 761
Drosophila pseudoobscura	Query 716 IGVLLLVIWKALTHLTDLREYRRFEKEKLK#SQWNNDNPLFKSATTTVMNPK 766 \|\|+\|\|+ ++ \| \|\|\| \|\|\|+\|+ \|# + + +\|\|\|++ + \|\| Sbjct 710 IGLLLIFLFIWCIRRKDAREYARFEEEQAK#-RVSQENPLYRDPVGRYVVPK 759

[Site 2] LFKSATTTVM⁷⁶³-NPKFAES

Met⁷⁶³ Asn

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Leu⁷⁵⁴	Phe⁷⁵⁵	Lys⁷⁵⁶	Ser⁷⁵⁷	Ala⁷⁵⁸	Thr⁷⁵⁹	Thr⁷⁶⁰	Thr⁷⁶¹	Val⁷⁶²	Met⁷⁶³

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Asn⁷⁶⁴	Pro⁷⁶⁵	Lys⁷⁶⁶	Phe⁷⁶⁷	Ala⁷⁶⁸	Glu⁷⁶⁹	Ser⁷⁷⁰	-	-	-

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
REYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES

Summary

#	organism	max score	hits	top seq
1	N/A	80.50	20	A
2	Homo sapiens	80.50	14	integrin, beta 2 precursor
3	Mus musculus	80.50	10	integrin beta 2
4	Pan troglodytes	80.50	6	integrin, beta 2
5	synthetic construct	80.50	3	integrin, beta 2 (antigen CD18 (p95), lymphocyte f
6	Rattus norvegicus	78.60	8	PREDICTED: similar to Integrin beta-2 precursor (C
7	Bos taurus	78.60	6	integrin, beta 2
8	Ovis canadensis	78.60	1	ITB2_OVICA Integrin beta-2 precursor (Cell surface
9	Sigmodon hispidus	78.60	1	AF445415_1 integrin beta-2 precursor
10	Capra hircus	78.60	1	ITB2_CAPHI Integrin beta-2 precursor (Cell surface
11	Ovis aries	78.60	1	antigen CD18
12	Bubalus bubalis	78.60	1	integrin beta-2
13	Sus scrofa	77.80	4	CD18 leukocyte adhesion molecule
14	Canis familiaris	75.50	4	AF181965_1 B-2 integrin
15	Gallus gallus	62.40	5	integrin, beta 2
16	Monodelphis domestica	61.20	4	PREDICTED: similar to Stromal interaction molecule
17	Xenopus laevis	48.90	5	hypothetical protein LOC379708
18	Mus sp.	48.90	1	beta 7 integrin
19	Macaca mulatta	48.50	2	PREDICTED: integrin, beta 7
20	Danio rerio	48.10	12	integrin, beta 1b
21	Tetraodon nigroviridis	48.10	5	unnamed protein product
22	Oryctolagus cuniculus	48.10	2	integrin beta 1
23	Ictalurus punctatus	48.10	2	beta-1 integrin
24	Xenopus tropicalis	48.10	1	integrin beta 1 (fibronectin receptor beta)
25	Felis catus	48.10	1	integrin beta 1
26	Pongo pygmaeus	48.10	1	ITB1_PONPY Integrin beta-1 precursor (Fibronectin
27	Oncorhynchus mykiss	47.00	1	CD18 protein
28	Anopheles gambiae	44.70	1	integrin beta subunit
29	Anopheles gambiae str. PEST	44.70	1	ENSANGP00000021373
30	Aedes aegypti	44.70	1	integrin beta subunit
31	Pacifastacus leniusculus	44.30	1	integrin
32	Cyprinus carpio	43.90	2	CD18 type 2
33	Drosophila melanogaster	43.50	1	myospheroid CG1560-PA
34	Tribolium castaneum	43.10	2	PREDICTED: similar to CG1560-PA
35	Pseudoplusia includens	43.10	1	integrin beta 1
36	Ostrinia furnacalis	43.10	1	integrin beta 1 precursor
37	Caenorhabditis briggsae	42.00	1	Hypothetical protein CBG03601
38	Apis mellifera	42.00	1	PREDICTED: similar to myospheroid CG1560-PA
39	Strongylocentrotus purpuratus	41.20	5	integrin beta L subunit
40	Caenorhabditis elegans	40.80	1	Paralysed Arrest at Two-fold family member (pat-3)
41	Crassostrea gigas	40.40	1	integrin beta cgh
42	Acropora millepora	40.40	1	integrin subunit betaCn1
43	Biomphalaria glabrata	39.30	1	beta integrin subunit
44	Podocoryne carnea	38.10	1	AF308652_1 integrin beta chain
45	Lytechinus variegatus	35.00	1	beta-C integrin subunit
46	mice, Peptide Partial, 680 aa	34.70	1	beta 3 integrin, GPIIIA
47	rats, Peptide Partial, 723 aa	34.70	1	beta 3 integrin, GPIIIA
48	Canis lupus familiaris	34.70	1	integrin beta chain, beta 3
49	Equus caballus	34.70	1	integrin, beta 3 (platelet glycoprotein IIIa, anti
50	Schistosoma japonicum	33.90	1	SJCHGC06221 protein

Top-ranked sequences

organism	matching
N/A	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Homo sapiens	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Mus musculus	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Pan troglodytes	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
synthetic construct	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Rattus norvegicus	Query 735 EYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Query 735 EYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Bos taurus	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 733 REYHRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 769
Ovis canadensis	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 734 REYHRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Sigmodon hispidus	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 733 REYRHFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 769
Capra hircus	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 734 REYHRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Ovis aries	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 734 REYHRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770
Bubalus bubalis	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\| Sbjct 733 REYHRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 769
Sus scrofa	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAE 769 \|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\| Sbjct 733 REYKRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAE 768
Canis familiaris	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|++\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|+\|\|\|\| Sbjct 728 REFKRFEKEKLRSQWNNDNPLFKSATTTVM#NPRFAES 764
Gallus gallus	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|\|\|\|\|\|\|\|\| \|++\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|+\| Sbjct 735 REYRRFEKEKSKAKWNEADNPLFKSATTTVM#NPRF 769
Monodelphis domestica	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NP 765 \|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|++# \| Sbjct 1199 REYKRFEKEKLKSQWNNDNPLFKKKTTTII#IP 1230
Xenopus laevis	Query 735 EYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKFA 768 \|\|+\|\|\|\|\|++ \|+\|\| \|\|\|+ +\|\|\|\|\| #\|\| \|+ Sbjct 736 EYQRFEKERMNSKWNPGHNPLYHNATTTVQ#NPNFS 770
Mus sp.	Query 734 REYRRFEKEKLKSQWNND-NPLFKSATTTVM#NPKF 767 \|\|\|\|\|\|\|\|\|+ + \| \| \|\|\|+\|\|\| \|\| +#\|\|+\| Sbjct 755 REYRRFEKEQQQLNWKQDNNPLYKSAITTTV#NPRF 789
Macaca mulatta	Query 734 REYRRFEKEKLKSQWNND-NPLFKSATTTVM#NPKFAES 770 \|\|\| \|\|\|\|\|+ + \| \| \|\|\|+\|\|\| \|\| +#\|\|+\| \|+ Sbjct 632 REYSRFEKEQQQLNWKQDSNPLYKSAITTTI#NPRFQEA 669
Danio rerio	Query 734 REYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 758 REFAKFEKEKMNAKWDAGENPIYKSAVTTVV#NPKY 792
Tetraodon nigroviridis	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 754 REFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 788
Oryctolagus cuniculus	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 26 REFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 60
Ictalurus punctatus	Query 734 REYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 770 REFAKFEKEKMNAKWDAGENPIYKSAVTTVV#NPKY 804
Xenopus tropicalis	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795
Felis catus	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795
Pongo pygmaeus	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|\|+#\|\|\|+ Sbjct 761 REFAKFEKEKMNAKWDTGENPIYKSAVTTVV#NPKY 795
Oncorhynchus mykiss	Query 734 REYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKF 767 +\|+\|\|\|\| \|+ \| +\|+ \|\|\|\|\| +\|\|\|\|\| #\|\| \| Sbjct 740 KEFRRFENEQKKGKWSPGDNPLFMNATTTVA#NPTF 774
Anopheles gambiae	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\| #\|\| +\| Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATTTFK#NPTYA 835
Anopheles gambiae str. PEST	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\| #\|\| +\| Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATTTFK#NPTYA 835
Aedes aegypti	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\| #\|\| +\| Sbjct 798 REFARFEKERMMAKWDTGENPIYKQATTTFK#NPTYA 833
Pacifastacus leniusculus	Query 734 REYRRFEKE-KLKSQWNNDNPLFKSATTTVM#NPKFAES 770 \|\|\| +\|\|\|\| \|\| \| +\|\|\|+\|\|\| \|\| #\|\| \|\|+\| Sbjct 763 REYAKFEKERKLPSGKRAENPLYKSAKTTFQ#NPAFAQS 800
Cyprinus carpio	Query 734 REYRRFEKEKLKSQWNNDNPLFKSATTTVM#NPKFA 768 \|\|++\|\|\|\|++ + + \|\|\|\|++\|\|\|\|\| #\|\| \|+ Sbjct 730 REWKRFEKDRKHEKTSGTNPLFQNATTTVQ#NPTFS 764
Drosophila melanogaster	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\| #\|\| +\| Sbjct 809 REFARFEKERMNAKWDTGENPIYKQATSTFK#NPMYA 844
Tribolium castaneum	Query 734 REYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKF 767 +\|\| +\|\| \|+ \| \|\|+ \|\|\|\|\|++ \|\|+\| #\|\| + Sbjct 717 QEYAKFENERQKMQWHRNDNPLYRQATSTFK#NPVY 751
Pseudoplusia includens	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\| #\|\| +\| Sbjct 800 REFARFEKERMMAKWDTGENPIYKQATSTFK#NPTYA 835
Ostrinia furnacalis	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFA 768 \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\| #\|\| +\| Sbjct 794 REFARFEKERMMAKWDTGENPIYKQATSTFK#NPTYA 829
Caenorhabditis briggsae	Query 735 EYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKFA 768 \|\| +\| \|+\| ++\|+ \|+\|\|++\| \|\|\|\| #\|\| +\| Sbjct 772 EYAKFNNERLMAKWDTNENPIYKQATTTFK#NPVYA 806
Apis mellifera	Query 734 REYRRFEKEK-LKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+++\|\|+\|+ \| ++\|\| \|\|\|\|+\| \|\|+\| #\|\| \| Sbjct 778 REFKKFERERILANKWNRRDNPLYKEATSTFK#NPTF 813
Strongylocentrotus purpuratus	Query 734 REYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKFAE 769 \|\|\| ++\| + \|+\|\|+ +\|\|\|++\|\|+\|\|\| #\|\| + + Sbjct 766 REYAQWENDCKKAQWDQSDNPIYKSSTTTFK#NPTYGK 802
Caenorhabditis elegans	Query 735 EYRRFEKEKLKSQWN-NDNPLFKSATTTVM#NPKFA 768 \|\| \| \|+\| ++\|+ \|+\|\|++\| \|\|\|\| #\|\| +\| Sbjct 771 EYATFNNERLMAKWDTNENPIYKQATTTFK#NPVYA 805
Crassostrea gigas	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFAE 769 \|\| \|\|\|\|\| + ++\|+ +\|\|++\| \|\|+\| +#\|\| + + Sbjct 763 RELARFEKEAMNARWDTGENPIYKQATSTFV#NPTYRQ 799
Acropora millepora	Query 735 EYRRFEKEKLKSQWNND-NPLFKSATTTVM#NPKFA 768 \|\|++\|\|+\|++ \|+\| + \|\|\|+++\| \|\| #\|\| +\| Sbjct 754 EYQKFERERMHSKWTREKNPLYQAAKTTFE#NPTYA 788
Biomphalaria glabrata	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|\|+ ++\|+ +\|\|++\| \|\|+\| #\|\| + Sbjct 751 REFAKFEKERQNAKWDTGENPIYKQATSTFK#NPTY 785
Podocoryne carnea	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKF 767 \|\|+ +\|\|\|++ +\|++ +\|\|++\| \|\|+\| #\|\| + Sbjct 744 REFAKFEKDRQNPKWDSGENPIYKKATSTFQ#NPMY 778
Lytechinus variegatus	Query 734 REYRRFEKEKLKSQW-NNDNPLFKSATTTVM#NPKF 767 \|\|++ \|\|\|\|+ + \| +\|\|++\| +\|+ #\|\| + Sbjct 769 REFQNFEKERANATWEGGENPIYKPSTSVFK#NPTY 803
mice, Peptide Partial, 680 aa	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#N 764 +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\| #\| Sbjct 647 KEFAKFEEERARAKWDTANNPLYKEATSTFT#N 678
rats, Peptide Partial, 723 aa	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#N 764 +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\| #\| Sbjct 686 KEFAKFEEERARAKWDTANNPLYKEATSTFT#N 717
Canis lupus familiaris	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#N 764 +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\| #\| Sbjct 747 KEFAKFEEERARAKWDTANNPLYKEATSTFT#N 778
Equus caballus	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#N 764 +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\| #\| Sbjct 747 KEFAKFEEERARAKWDTANNPLYKEATSTFT#N 778
Schistosoma japonicum	Query 734 REYRRFEKEKLKSQWNN-DNPLFKSATTTVM#NPKFAES 770 \|\| \|+++ +\| +\|\|+\|+\| \|\| \|+#\|\| \| \|+ Sbjct 249 RELANFKQQGENMRWEMAENPIFESPTTNVL#NPTFEEN 286

[Site 3] NPLFKSATTT⁷⁶¹-VMNPKFAES

Thr⁷⁶¹ Val

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Asn⁷⁵²	Pro⁷⁵³	Leu⁷⁵⁴	Phe⁷⁵⁵	Lys⁷⁵⁶	Ser⁷⁵⁷	Ala⁷⁵⁸	Thr⁷⁵⁹	Thr⁷⁶⁰	Thr⁷⁶¹

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Val⁷⁶²	Met⁷⁶³	Asn⁷⁶⁴	Pro⁷⁶⁵	Lys⁷⁶⁶	Phe⁷⁶⁷	Ala⁷⁶⁸	Glu⁷⁶⁹	Ser⁷⁷⁰	-

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
DLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES

Summary

#	organism	max score	hits	top seq
1	N/A	84.30	20	A
2	Homo sapiens	84.30	14	leukocyte adhesion protein beta-subunit precursor
3	Mus musculus	84.30	10	integrin beta 2
4	Pan troglodytes	84.30	6	integrin, beta 2
5	synthetic construct	84.30	3	integrin, beta 2 (antigen CD18 (p95), lymphocyte f
6	Rattus norvegicus	82.40	8	PREDICTED: similar to Integrin beta-2 precursor (C
7	Bos taurus	82.40	6	integrin, beta 2
8	Sigmodon hispidus	82.40	1	AF445415_1 integrin beta-2 precursor
9	Capra hircus	82.40	1	ITB2_CAPHI Integrin beta-2 precursor (Cell surface
10	Bubalus bubalis	82.40	1	integrin beta-2
11	Ovis aries	82.40	1	antigen CD18
12	Ovis canadensis	82.40	1	ITB2_OVICA Integrin beta-2 precursor (Cell surface
13	Sus scrofa	81.60	4	CD18 leukocyte adhesion molecule
14	Canis familiaris	79.30	4	AF181965_1 B-2 integrin
15	Monodelphis domestica	65.10	4	PREDICTED: similar to Stromal interaction molecule
16	Gallus gallus	63.90	5	integrin, beta 2
17	Xenopus laevis	50.40	5	hypothetical protein LOC379708
18	Mus sp.	50.40	1	beta 7 integrin
19	Macaca mulatta	50.10	2	PREDICTED: integrin, beta 7
20	Felis catus	50.10	1	integrin beta 1
21	Danio rerio	49.70	12	integrin, beta 1b
22	Tetraodon nigroviridis	49.70	6	unnamed protein product
23	Oryctolagus cuniculus	49.70	2	integrin beta 1
24	Ictalurus punctatus	49.70	2	beta-1 integrin
25	Oncorhynchus mykiss	49.70	1	CD18 protein
26	Pongo pygmaeus	49.70	1	ITB1_PONPY Integrin beta-1 precursor (Fibronectin
27	Xenopus tropicalis	49.70	1	integrin beta 1 (fibronectin receptor beta)
28	Cyprinus carpio	47.80	2	CD18 type 2
29	Anopheles gambiae str. PEST	46.20	1	ENSANGP00000021373
30	Anopheles gambiae	46.20	1	integrin beta subunit
31	Aedes aegypti	46.20	1	integrin beta subunit
32	Pacifastacus leniusculus	45.80	1	integrin
33	Drosophila melanogaster	45.10	1	myospheroid CG1560-PA
34	Tribolium castaneum	44.70	3	PREDICTED: similar to CG1560-PA
35	Pseudoplusia includens	44.70	1	integrin beta 1
36	Ostrinia furnacalis	44.70	1	integrin beta 1 precursor
37	Apis mellifera	43.10	1	PREDICTED: similar to myospheroid CG1560-PA
38	Caenorhabditis briggsae	43.10	1	Hypothetical protein CBG03601
39	Strongylocentrotus purpuratus	42.70	5	integrin beta L subunit
40	Caenorhabditis elegans	42.00	1	Paralysed Arrest at Two-fold family member (pat-3)
41	Crassostrea gigas	42.00	1	integrin beta cgh
42	Biomphalaria glabrata	41.20	1	beta integrin subunit
43	Acropora millepora	40.80	1	integrin subunit betaCn1
44	Podocoryne carnea	39.70	1	AF308652_1 integrin beta chain
45	Lytechinus variegatus	36.60	1	beta-C integrin subunit
46	Equus caballus	36.20	1	integrin, beta 3 (platelet glycoprotein IIIa, anti
47	Canis lupus familiaris	36.20	1	integrin beta chain, beta 3
48	rats, Peptide Partial, 723 aa	36.20	1	beta 3 integrin, GPIIIA
49	mice, Peptide Partial, 680 aa	36.20	1	beta 3 integrin, GPIIIA
50	Schistosoma japonicum	35.40	1	SJCHGC06221 protein
51	Ophlitaspongia tenuis	33.50	1	integrin subunit betaPo1
52	Geodia cydonium	33.10	1	integrin beta subunit

Top-ranked sequences

organism	matching
N/A	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Homo sapiens	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Mus musculus	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Pan troglodytes	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
synthetic construct	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Rattus norvegicus	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 730 DLNEYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 768
Bos taurus	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 731 DLREYHRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 769
Sigmodon hispidus	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 731 DLREYRHFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 769
Capra hircus	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 732 DLREYHRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Bubalus bubalis	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 731 DLREYHRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 769
Ovis aries	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 732 DLREYHRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Ovis canadensis	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\| Sbjct 732 DLREYHRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770
Sus scrofa	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAE 769 \|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\| Sbjct 731 DLREYKRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAE 768
Canis familiaris	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \|\|\|\|++\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|+\|\|\|\| Sbjct 726 DLREFKRFEKEKLRSQWNNDNPLFKSATTT#VMNPRFAES 764
Monodelphis domestica	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNP 765 \|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| \|\|\|#++ \| Sbjct 1197 DLREYKRFEKEKLKSQWNNDNPLFKKKTTT#IIIP 1230
Gallus gallus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|\|\|\|\|\|\|\|\| \|++\|\| \|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|+\| Sbjct 733 DRREYRRFEKEKSKAKWNEADNPLFKSATTT#VMNPRF 769
Xenopus laevis	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\|+\|\|\|\|\|++ \|+\|\| \|\|\|+ +\|\|\|\|#\| \|\| \|+ Sbjct 733 DRNEYQRFEKERMNSKWNPGHNPLYHNATTT#VQNPNFS 770
Mus sp.	Query 732 DLREYRRFEKEKLKSQWNND-NPLFKSATTT#VMNPKF 767 \| \|\|\|\|\|\|\|\|\|+ + \| \| \|\|\|+\|\|\| \|\|# +\|\|+\| Sbjct 753 DRREYRRFEKEQQQLNWKQDNNPLYKSAITT#TVNPRF 789
Macaca mulatta	Query 732 DLREYRRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFAES 770 \| \|\|\| \|\|\|\|\|+ + \| \| \|\|\|+\|\|\| \|\|# +\|\|+\| \|+ Sbjct 630 DRREYSRFEKEQQQLNWKQDSNPLYKSAITT#TINPRFQEA 669
Felis catus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 759 DTREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795
Danio rerio	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 756 DRREFAKFEKEKMNAKWDAGENPIYKSAVTT#VVNPKY 792
Tetraodon nigroviridis	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 752 DRREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 788
Oryctolagus cuniculus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 24 DRREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 60
Ictalurus punctatus	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 768 DRREFAKFEKEKMNAKWDAGENPIYKSAVTT#VVNPKY 804
Oncorhynchus mykiss	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKF 767 \|++\|+\|\|\|\| \|+ \| +\|+ \|\|\|\|\| +\|\|\|\|#\| \|\| \| Sbjct 738 DVKEFRRFENEQKKGKWSPGDNPLFMNATTT#VANPTF 774
Pongo pygmaeus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 759 DRREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795
Xenopus tropicalis	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++\|\|\| \|\|#\|+\|\|\|+ Sbjct 759 DRREFAKFEKEKMNAKWDTGENPIYKSAVTT#VVNPKY 795
Cyprinus carpio	Query 732 DLREYRRFEKEKLKSQWNNDNPLFKSATTT#VMNPKFA 768 \|\|\|\|++\|\|\|\|++ + + \|\|\|\|++\|\|\|\|#\| \|\| \|+ Sbjct 728 DLREWKRFEKDRKHEKTSGTNPLFQNATTT#VQNPTFS 764
Anopheles gambiae str. PEST	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\|# \|\| +\| Sbjct 798 DRREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTYA 835
Anopheles gambiae	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\|# \|\| +\| Sbjct 798 DRREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTYA 835
Aedes aegypti	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|\|\|# \|\| +\| Sbjct 796 DRREFARFEKERMMAKWDTGENPIYKQATTT#FKNPTYA 833
Pacifastacus leniusculus	Query 732 DLREYRRFEKE-KLKSQWNNDNPLFKSATTT#VMNPKFAES 770 \| \|\|\| +\|\|\|\| \|\| \| +\|\|\|+\|\|\| \|\|# \|\| \|\|+\| Sbjct 761 DRREYAKFEKERKLPSGKRAENPLYKSAKTT#FQNPAFAQS 800
Drosophila melanogaster	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\|# \|\| +\| Sbjct 807 DRREFARFEKERMNAKWDTGENPIYKQATST#FKNPMYA 844
Tribolium castaneum	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKF 767 \| +\|\| +\|\| \|+ \| \|\|+ \|\|\|\|\|++ \|\|+\|# \|\| + Sbjct 715 DRQEYAKFENERQKMQWHRNDNPLYRQATST#FKNPVY 751
Pseudoplusia includens	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\|# \|\| +\| Sbjct 798 DRREFARFEKERMMAKWDTGENPIYKQATST#FKNPTYA 835
Ostrinia furnacalis	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++\| \|\|+\|# \|\| +\| Sbjct 792 DRREFARFEKERMMAKWDTGENPIYKQATST#FKNPTYA 829
Apis mellifera	Query 732 DLREYRRFEKEK-LKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+++\|\|+\|+ \| ++\|\| \|\|\|\|+\| \|\|+\|# \|\| \| Sbjct 776 DNREFKKFERERILANKWNRRDNPLYKEATST#FKNPTF 813
Caenorhabditis briggsae	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\| +\| \|+\| ++\|+ \|+\|\|++\| \|\|\|\|# \|\| +\| Sbjct 769 DRAEYAKFNNERLMAKWDTNENPIYKQATTT#FKNPVYA 806
Strongylocentrotus purpuratus	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFAE 769 \| \|\|\| ++\| + \|+\|\|+ +\|\|\|++\|\|+\|\|\|# \|\| + + Sbjct 764 DKREYAQWENDCKKAQWDQSDNPIYKSSTTT#FKNPTYGK 802
Caenorhabditis elegans	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFA 768 \| \|\| \| \|+\| ++\|+ \|+\|\|++\| \|\|\|\|# \|\| +\| Sbjct 768 DRSEYATFNNERLMAKWDTNENPIYKQATTT#FKNPVYA 805
Crassostrea gigas	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKFAE 769 \| \|\| \|\|\|\|\| + ++\|+ +\|\|++\| \|\|+\|# +\|\| + + Sbjct 761 DKRELARFEKEAMNARWDTGENPIYKQATST#FVNPTYRQ 799
Biomphalaria glabrata	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|\|+ ++\|+ +\|\|++\| \|\|+\|# \|\| + Sbjct 749 DTREFAKFEKERQNAKWDTGENPIYKQATST#FKNPTY 785
Acropora millepora	Query 732 DLREYRRFEKEKLKSQWNND-NPLFKSATTT#VMNPKFA 768 \| \|\|++\|\|+\|++ \|+\| + \|\|\|+++\| \|\|# \|\| +\| Sbjct 751 DRIEYQKFERERMHSKWTREKNPLYQAAKTT#FENPTYA 788
Podocoryne carnea	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKF 767 \| \|\|+ +\|\|\|++ +\|++ +\|\|++\| \|\|+\|# \|\| + Sbjct 742 DRREFAKFEKDRQNPKWDSGENPIYKKATST#FQNPMY 778
Lytechinus variegatus	Query 732 DLREYRRFEKEKLKSQW-NNDNPLFKSATTT#VMNPKF 767 \| \|\|++ \|\|\|\|+ + \| +\|\|++\| +\|+ # \|\| + Sbjct 767 DRREFQNFEKERANATWEGGENPIYKPSTSV#FKNPTY 803
Equus caballus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMN 764 \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\|# \| Sbjct 745 DRKEFAKFEEERARAKWDTANNPLYKEATST#FTN 778
Canis lupus familiaris	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMN 764 \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\|# \| Sbjct 745 DRKEFAKFEEERARAKWDTANNPLYKEATST#FTN 778
rats, Peptide Partial, 723 aa	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMN 764 \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\|# \| Sbjct 684 DRKEFAKFEEERARAKWDTANNPLYKEATST#FTN 717
mice, Peptide Partial, 680 aa	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMN 764 \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+\| \|\|+\|# \| Sbjct 645 DRKEFAKFEEERARAKWDTANNPLYKEATST#FTN 678
Schistosoma japonicum	Query 732 DLREYRRFEKEKLKSQWNN-DNPLFKSATTT#VMNPKFAES 770 \| \|\| \|+++ +\| +\|\|+\|+\| \|\| #\|+\|\| \| \|+ Sbjct 247 DRRELANFKQQGENMRWEMAENPIFESPTTN#VLNPTFEEN 286
Ophlitaspongia tenuis	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFAE 769 \|+ \| \|+\|\|+\| +++ \|+\|\|\|++\|\|\| # \|\| + + Sbjct 800 DVVEVRKFEREIKNAKYTKNENPLYRSATKD#YQNPLYGK 838
Geodia cydonium	Query 732 DLREYRRFEKEKLKSQWN-NDNPLFKSATTT#VMNPKFAE 769 \| \| ++\|\| \| \| ++ \|+\|\|\|+ \|\|\|\| # \|\| + + Sbjct 840 DYTELKKFENELAKVKYTKNENPLYHSATTE#HKNPIYGQ 878

[Site 4] SQWNNDNPLF⁷⁵⁵-KSATTTVMNP

Phe⁷⁵⁵ Lys

P10	P9	P8	P7	P6	P5	P4	P3	P2	P1

Ser⁷⁴⁶	Gln⁷⁴⁷	Trp⁷⁴⁸	Asn⁷⁴⁹	Asn⁷⁵⁰	Asp⁷⁵¹	Asn⁷⁵²	Pro⁷⁵³	Leu⁷⁵⁴	Phe⁷⁵⁵

P1'	P2'	P3'	P4'	P5'	P6'	P7'	P8'	P9'	P10'
Lys⁷⁵⁶	Ser⁷⁵⁷	Ala⁷⁵⁸	Thr⁷⁵⁹	Thr⁷⁶⁰	Thr⁷⁶¹	Val⁷⁶²	Met⁷⁶³	Asn⁷⁶⁴	Pro⁷⁶⁵

Sequence conservation (by blast) Sequence conservation (by blast)

Reference peptide (cleaved bond±30 residues)
ALTHLTDLREYRRFEKEKLKSQWNNDNPLFKSATTTVMNPKFAES

Summary

#	organism	max score	hits	top seq
1	N/A	95.90	20	I
2	Mus musculus	95.90	10	integrin beta 2
3	Rattus norvegicus	94.00	8	PREDICTED: similar to Integrin beta-2 precursor (C
4	Sigmodon hispidus	94.00	1	AF445415_1 integrin beta-2 precursor
5	Bos taurus	92.40	6	integrin, beta 2
6	Ovis aries	92.40	1	antigen CD18
7	Ovis canadensis	92.40	1	ITB2_OVICA Integrin beta-2 precursor (Cell surface
8	Bubalus bubalis	92.40	1	integrin beta-2
9	Capra hircus	92.40	1	ITB2_CAPHI Integrin beta-2 precursor (Cell surface
10	Homo sapiens	92.00	14	integrin beta chain, beta 2 precursor variant
11	Pan troglodytes	92.00	6	integrin, beta 2
12	synthetic construct	92.00	3	integrin, beta 2 (antigen CD18 (p95), lymphocyte f
13	Sus scrofa	90.10	4	CD18 leukocyte adhesion molecule
14	Canis familiaris	89.40	4	AF181965_1 B-2 integrin
15	Monodelphis domestica	72.00	4	PREDICTED: similar to Stromal interaction molecule
16	Gallus gallus	67.40	6	integrin, beta 2
17	Xenopus laevis	53.50	5	hypothetical protein LOC379708
18	Oncorhynchus mykiss	52.80	1	CD18 protein
19	Ictalurus punctatus	50.80	2	CD18
20	Mus sp.	50.40	1	beta 7 integrin
21	Cyprinus carpio	50.10	2	CD18 type 2
22	Macaca mulatta	50.10	2	PREDICTED: integrin, beta 7
23	Felis catus	50.10	1	integrin beta 1
24	Danio rerio	49.70	12	integrin, beta 1b
25	Tetraodon nigroviridis	49.70	6	unnamed protein product
26	Oryctolagus cuniculus	49.70	2	integrin beta 1
27	Pongo pygmaeus	49.70	1	ITB1_PONPY Integrin beta-1 precursor (Fibronectin
28	Xenopus tropicalis	49.70	1	integrin beta 1 (fibronectin receptor beta)
29	Pacifastacus leniusculus	49.30	1	integrin
30	Anopheles gambiae str. PEST	49.30	1	ENSANGP00000021373
31	Anopheles gambiae	49.30	1	integrin beta subunit
32	Aedes aegypti	48.90	1	integrin beta subunit
33	Drosophila melanogaster	47.80	1	myospheroid CG1560-PA
34	Apis mellifera	46.20	1	PREDICTED: similar to myospheroid CG1560-PA
35	Caenorhabditis briggsae	46.20	1	Hypothetical protein CBG03601
36	Ostrinia furnacalis	46.20	1	integrin beta 1 precursor
37	Strongylocentrotus purpuratus	45.40	5	integrin beta L subunit
38	Tribolium castaneum	45.40	3	PREDICTED: similar to CG1560-PA
39	Caenorhabditis elegans	45.10	1	Paralysed Arrest at Two-fold family member (pat-3)
40	Pseudoplusia includens	44.70	1	integrin beta 1
41	Crassostrea gigas	44.30	1	integrin beta cgh
42	Biomphalaria glabrata	44.30	1	beta integrin subunit
43	Acropora millepora	41.60	1	integrin subunit betaCn1
44	Podocoryne carnea	40.80	1	AF308652_1 integrin beta chain
45	Lytechinus variegatus	40.80	1	beta-C integrin subunit
46	Canis lupus familiaris	36.60	1	integrin beta chain, beta 3
47	mice, Peptide Partial, 680 aa	36.60	1	beta 3 integrin, GPIIIA
48	rats, Peptide Partial, 723 aa	36.60	1	beta 3 integrin, GPIIIA
49	Equus caballus	36.60	1	integrin, beta 3 (platelet glycoprotein IIIa, anti
50	Schistosoma japonicum	35.80	1	SJCHGC06221 protein
51	Ophlitaspongia tenuis	34.30	1	integrin subunit betaPo1
52	Geodia cydonium	33.50	1	integrin beta subunit

Top-ranked sequences

organism	matching
N/A	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770
Mus musculus	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770
Rattus norvegicus	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 724 ALTHLTDLNEYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 768
Sigmodon hispidus	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|\|\|\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALTHLTDLREYRHFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
Bos taurus	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALTHLSDLREYHRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
Ovis aries	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 726 ALTHLSDLREYHRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770
Ovis canadensis	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 726 ALTHLSDLREYHRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770
Bubalus bubalis	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALTHLSDLREYHRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
Capra hircus	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|\| \|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 726 ALTHLSDLREYHRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770
Homo sapiens	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALIHLSDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
Pan troglodytes	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALIHLSDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
synthetic construct	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\| \|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 725 ALIHLSDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 769
Sus scrofa	Query 727 LTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAE 769 \|\|\|\|+\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|\|\|\|\| Sbjct 726 LTHLSDLREYKRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAE 768
Canis familiaris	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\|\|\|\|+\|\|\|\|++\|\|\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|+\|\|\|\| Sbjct 720 ALTHLSDLREFKRFEKEKLRSQWNNDNPLF#KSATTTVMNPRFAES 764
Monodelphis domestica	Query 727 LTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNP 765 \|\|\| +\|\|\|\|\|+\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|\|#\| \|\|\|++ \| Sbjct 1192 LTHFSDLREYKRFEKEKLKSQWNNDNPLF#KKKTTTIIIP 1230
Gallus gallus	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \|\| + \| \|\|\|\|\|\|\|\|\|\| \|++\|\| \|\|\|\|\|#\|\|\|\|\|\|\|\|\|\|+\| Sbjct 728 LTEIFDRREYRRFEKEKSKAKWNEADNPLF#KSATTTVMNPRF 769
Xenopus laevis	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 +\| + \| \|\|+\|\|\|\|\|++ \|+\|\| \|\|\|+# +\|\|\|\|\| \|\| \|+ Sbjct 728 ITEIKDRNEYQRFEKERMNSKWNPGHNPLY#HNATTTVQNPNFS 770
Oncorhynchus mykiss	Query 726 ALTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKF 767 \|+ ++ \|++\|+\|\|\|\| \|+ \| +\|+ \|\|\|\|\|# +\|\|\|\|\| \|\| \| Sbjct 732 AILYMRDVKEFRRFENEQKKGKWSPGDNPLF#MNATTTVANPTF 774
Ictalurus punctatus	Query 726 ALTHLTDLREYRRFEKEKLKSQW-NNDNPLF#KSATTTVMNPKF 767 \|\| + \|\|+\|+++\|\|\|\| + \|\| +\|\|\|\|#++\|\|\|\|\| \|\| \| Sbjct 726 ALFYFKDLKEWKKFEKEAQRRQWAKGENPLF#QNATTTVANPAF 768
Mus sp.	Query 732 DLREYRRFEKEKLKSQWNND-NPLF#KSATTTVMNPKF 767 \| \|\|\|\|\|\|\|\|\|+ + \| \| \|\|\|+#\|\|\| \|\| +\|\|+\| Sbjct 753 DRREYRRFEKEQQQLNWKQDNNPLY#KSAITTTVNPRF 789
Cyprinus carpio	Query 726 ALTHLTDLREYRRFEKEKLKSQWNNDNPLF#KSATTTVMNPKFA 768 \|+ + +\|\|\|\|++\|\|\|\|++ + + \|\|\|\|#++\|\|\|\|\| \|\| \|+ Sbjct 722 AVLYASDLREWKRFEKDRKHEKTSGTNPLF#QNATTTVQNPTFS 764
Macaca mulatta	Query 732 DLREYRRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFAES 770 \| \|\|\| \|\|\|\|\|+ + \| \| \|\|\|+#\|\|\| \|\| +\|\|+\| \|+ Sbjct 630 DRREYSRFEKEQQQLNWKQDSNPLY#KSAITTTINPRFQEA 669
Felis catus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 759 DTREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKY 795
Danio rerio	Query 732 DLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 756 DRREFAKFEKEKMNAKWDAGENPIY#KSAVTTVVNPKY 792
Tetraodon nigroviridis	Query 732 DLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 752 DRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKY 788
Oryctolagus cuniculus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 24 DRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKY 60
Pongo pygmaeus	Query 732 DLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 759 DRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKY 795
Xenopus tropicalis	Query 732 DLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| \|\|+ +\|\|\|\|\|+ ++\|+ +\|\|++#\|\|\| \|\|\|+\|\|\|+ Sbjct 759 DRREFAKFEKEKMNAKWDTGENPIY#KSAVTTVVNPKY 795
Pacifastacus leniusculus	Query 727 LTHLTDLREYRRFEKE-KLKSQWNNDNPLF#KSATTTVMNPKFAES 770 \|\| \| \| \|\|\| +\|\|\|\| \|\| \| +\|\|\|+#\|\|\| \|\| \|\| \|\|+\| Sbjct 756 LTTLHDRREYAKFEKERKLPSGKRAENPLY#KSAKTTFQNPAFAQS 800
Anopheles gambiae str. PEST	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| + \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|\|\| \|\| +\| Sbjct 793 LTSIHDRREFARFEKERMMAKWDTGENPIY#KQATTTFKNPTYA 835
Anopheles gambiae	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| + \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|\|\| \|\| +\| Sbjct 793 LTSIHDRREFARFEKERMMAKWDTGENPIY#KQATTTFKNPTYA 835
Aedes aegypti	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| + \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|\|\| \|\| +\| Sbjct 791 LTTIHDRREFARFEKERMMAKWDTGENPIY#KQATTTFKNPTYA 833
Drosophila melanogaster	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| + \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|+\| \|\| +\| Sbjct 802 LTTIHDRREFARFEKERMNAKWDTGENPIY#KQATSTFKNPMYA 844
Apis mellifera	Query 727 LTHLTDLREYRRFEKEK-LKSQWNN-DNPLF#KSATTTVMNPKF 767 \|\| + \| \|\|+++\|\|+\|+ \| ++\|\| \|\|\|\|+#\| \|\|+\| \|\| \| Sbjct 771 LTMIRDNREFKKFERERILANKWNRRDNPLY#KEATSTFKNPTF 813
Caenorhabditis briggsae	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| \| \| \|\| +\| \|+\| ++\|+ \|+\|\|++#\| \|\|\|\| \|\| +\| Sbjct 764 LTVLHDRAEYAKFNNERLMAKWDTNENPIY#KQATTTFKNPVYA 806
Ostrinia furnacalis	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 +\| + \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|+\| \|\| +\| Sbjct 787 VTTIHDRREFARFEKERMMAKWDTGENPIY#KQATSTFKNPTYA 829
Strongylocentrotus purpuratus	Query 728 THLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFAE 769 \|++ \| \|\|\| ++\| + \|+\|\|+ +\|\|\|++#\|\|+\|\|\| \|\| + + Sbjct 760 TYVQDKREYAQWENDCKKAQWDQSDNPIY#KSSTTTFKNPTYGK 802
Tribolium castaneum	Query 728 THLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKF 767 \| + \| +\|\| +\|\| \|+ \| \|\|+ \|\|\|\|\|+#+ \|\|+\| \|\| + Sbjct 711 TTVHDRQEYAKFENERQKMQWHRNDNPLY#RQATSTFKNPVY 751
Caenorhabditis elegans	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \|\| \| \| \|\| \| \|+\| ++\|+ \|+\|\|++#\| \|\|\|\| \|\| +\| Sbjct 763 LTVLHDRSEYATFNNERLMAKWDTNENPIY#KQATTTFKNPVYA 805
Pseudoplusia includens	Query 732 DLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFA 768 \| \|\|+ \|\|\|\|\|++ ++\|+ +\|\|++#\| \|\|+\| \|\| +\| Sbjct 798 DRREFARFEKERMMAKWDTGENPIY#KQATSTFKNPTYA 835
Crassostrea gigas	Query 728 THLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFAE 769 \| ++\| \|\| \|\|\|\|\| + ++\|+ +\|\|++#\| \|\|+\| +\|\| + + Sbjct 757 TTISDKRELARFEKEAMNARWDTGENPIY#KQATSTFVNPTYRQ 799
Biomphalaria glabrata	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKF 767 \|\| + \| \|\|+ +\|\|\|\|+ ++\|+ +\|\|++#\| \|\|+\| \|\| + Sbjct 744 LTFIHDTREFAKFEKERQNAKWDTGENPIY#KQATSTFKNPTY 785
Acropora millepora	Query 730 LTDLREYRRFEKEKLKSQWNND-NPLF#KSATTTVMNPKFA 768 + \| \|\|++\|\|+\|++ \|+\| + \|\|\|+#++\| \|\| \|\| +\| Sbjct 749 MVDRIEYQKFERERMHSKWTREKNPLY#QAAKTTFENPTYA 788
Podocoryne carnea	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKF 767 \| + \| \|\|+ +\|\|\|++ +\|++ +\|\|++#\| \|\|+\| \|\| + Sbjct 737 LATIQDRREFAKFEKDRQNPKWDSGENPIY#KKATSTFQNPMY 778
Lytechinus variegatus	Query 727 LTHLTDLREYRRFEKEKLKSQW-NNDNPLF#KSATTTVMNPKF 767 \|\|++ \| \|\|++ \|\|\|\|+ + \| +\|\|++#\| +\|+ \|\| + Sbjct 762 LTYIHDRREFQNFEKERANATWEGGENPIY#KPSTSVFKNPTY 803
Canis lupus familiaris	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMN 764 \| + \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+#\| \|\|+\| \| Sbjct 740 LITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTN 778
mice, Peptide Partial, 680 aa	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMN 764 \| + \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+#\| \|\|+\| \| Sbjct 640 LITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTN 678
rats, Peptide Partial, 723 aa	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMN 764 \| + \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+#\| \|\|+\| \| Sbjct 679 LITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTN 717
Equus caballus	Query 727 LTHLTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMN 764 \| + \| +\|+ +\|\|+\|+ +++\|+ +\|\|\|+#\| \|\|+\| \| Sbjct 740 LITIHDRKEFAKFEEERARAKWDTANNPLY#KEATSTFTN 778
Schistosoma japonicum	Query 730 LTDLREYRRFEKEKLKSQWNN-DNPLF#KSATTTVMNPKFAES 770 + \| \|\| \|+++ +\| +\|\|+\|#+\| \|\| \|+\|\| \| \|+ Sbjct 245 IDDRRELANFKQQGENMRWEMAENPIF#ESPTTNVLNPTFEEN 286
Ophlitaspongia tenuis	Query 730 LTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFAE 769 \| \|+ \| \|+\|\|+\| +++ \|+\|\|\|+#+\|\|\| \|\| + + Sbjct 798 LWDVVEVRKFEREIKNAKYTKNENPLY#RSATKDYQNPLYGK 838
Geodia cydonium	Query 727 LTHLTDLREYRRFEKEKLKSQWN-NDNPLF#KSATTTVMNPKFAE 769 \| + \| \| ++\|\| \| \| ++ \|+\|\|\|+# \|\|\|\| \|\| + + Sbjct 835 LLMVLDYTELKKFENELAKVKYTKNENPLY#HSATTEHKNPIYGQ 878

* References

[PubMed ID: 19299700] Sorgi CA, Secatto A, Fontanari C, Turato WM, Belanger C, de Medeiros AI, Kashima S, Marleau S, Covas DT, Bozza PT, Faccioli LH, Histoplasma capsulatum cell wall {beta}-glucan induces lipid body formation through CD18, TLR2, and dectin-1 receptors: correlation with leukotriene B4 generation and role in HIV-1 infection. J Immunol. 2009 Apr 1;182(7):4025-35.

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