logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1009 : PREDICTED: similar to Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP-4) (IGF-binding protein 4) isoform 2 [Pan troglodytes]

[ CaMP Format ]

This entry is computationally expanded from SB0070

* Basic Information

OrganismPan troglodytes (chimpanzee)
Protein Namessimilar to Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP-4) (IGF-binding protein 4) isoform 2
Gene NamesLOC454652; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 7 mRNAs, 1384 ESTs, 14 Proteins
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_511475 XM_511475 454652 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 258 aa

Average Mass: 27.948 kDa

Monoisotopic Mass: 27.929 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 2785102.02.1e-27
--- cleavage 143 ---
--- cleavage 159 ---
--- cleavage 107 ---
Thyroglobulin_1 1. 174249144.04.7e-40

3. Sequence Information

Fasta Sequence: XSB1009.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

3 [sites]

Cleavage sites (±10aa)

[Site 1] HDRRCLQKHF143-AKIRDRSTSG

Phe143 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
His134Asp135Arg136Arg137Cys138Leu139Gln140Lys141His142Phe143
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala144Lys145Ile146Arg147Asp148Arg149Ser150Thr151Ser152Gly153

Sequence conservation (by blast)

[Site 2] STSGGKMKVN159-GAPREDARPV

Asn159 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser150Thr151Ser152Gly153Gly154Lys155Met156Lys157Val158Asn159
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly160Ala161Pro162Arg163Glu164Asp165Ala166Arg167Pro168Val169

Sequence conservation (by blast)

[Site 3] GLCMELAEIE107-AIQESLQPSD

Glu107 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly98Leu99Cys100Met101Glu102Leu103Ala104Glu105Ile106Glu107
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala108Ile109Gln110Glu111Ser112Leu113Gln114Pro115Ser116Asp117

Sequence conservation (by blast)

* References

None.