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XSB1015 : phosphodiesterase 1A [Canis lupus familiaris]

[ CaMP Format ]

This entry is computationally expanded from SB0004

* Basic Information

OrganismCanis lupus familiaris (dog)
Protein NamesCalmodulin-activated cyclic nucleotide phosphodiesterase; phosphodiesterase 1A
Gene NamesPDE1A; phosphodiesterase 1A, calmodulin-dependent
Gene Locus36; chromosome 36
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001003091 NM_001003091 403652 Q95NB8 N/A N/A N/A cfa:403652

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 515 aa

Average Mass: 59.375 kDa

Monoisotopic Mass: 59.337 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
PDEase_I_N 1. 57117123.85.4e-34
--- cleavage 110 (inside PDEase_I_N 57..117) ---
PDEase_I 1. 202433505.66.5e-149

3. Sequence Information

Fasta Sequence: XSB1015.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] KFRSIVHAVQ110-AGIFVERMYR

Gln110 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys101Phe102Arg103Ser104Ile105Val106His107Ala108Val109Gln110
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala111Gly112Ile113Phe114Val115Glu116Arg117Met118Tyr119Arg120

Sequence conservation (by blast)

* References

[PubMed ID: 11368912] Clapham JC, Wilderspin AF, Cloning of dog heart PDE1A - a first detailed characterization at the molecular level in this species. Gene. 2001 May 2;268(1-2):165-71.