logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB1036 : hCG2001034 [Homo sapiens]

[ CaMP Format ]

This entry is computationally expanded from SB0063

* Basic Information

OrganismHomo sapiens (human)
Protein NameshCG2001034
Gene NamesNot available
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EAW84441 N/A N/A N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 219 aa

Average Mass: 24.723 kDa

Monoisotopic Mass: 24.706 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
EGF_2 1. 205133.77.6e-07
Integrin_B_tail 1. 61149159.01.4e-44
Integrin_b_cyt 1. 173218112.31.6e-30
--- cleavage 210 (inside Integrin_b_cyt 173..218) ---
--- cleavage 212 (inside Integrin_b_cyt 173..218) ---
--- cleavage 199 (inside Integrin_b_cyt 173..218) ---
--- cleavage 198 (inside Integrin_b_cyt 173..218) ---

3. Sequence Information

Fasta Sequence: XSB1036.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

4 [sites]

Cleavage sites (±10aa)

[Site 1] NPIYKSAVTT210-VVNPKYEGK

Thr210 Val

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn201Pro202Ile203Tyr204Lys205Ser206Ala207Val208Thr209Thr210
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Val211Val212Asn213Pro214Lys215Tyr216Glu217Gly218Lys219-

Sequence conservation (by blast)

[Site 2] IYKSAVTTVV212-NPKYEGK

Val212 Asn

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ile203Tyr204Lys205Ser206Ala207Val208Thr209Thr210Val211Val212
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Asn213Pro214Lys215Tyr216Glu217Gly218Lys219---

Sequence conservation (by blast)

[Site 3] EKMNAKWDTG199-ENPIYKSAVT

Gly199 Glu

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu190Lys191Met192Asn193Ala194Lys195Trp196Asp197Thr198Gly199
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Glu200Asn201Pro202Ile203Tyr204Lys205Ser206Ala207Val208Thr209

Sequence conservation (by blast)

[Site 4] KEKMNAKWDT198-GENPIYKSAV

Thr198 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Lys189Glu190Lys191Met192Asn193Ala194Lys195Trp196Asp197Thr198
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly199Glu200Asn201Pro202Ile203Tyr204Lys205Ser206Ala207Val208

Sequence conservation (by blast)

* References

[PubMed ID: 11181995] Venter JC, Adams MD, Myers EW, Li PW, Mural RJ, Sutton GG, Smith HO, Yandell M, Evans CA, Holt RA, Gocayne JD, Amanatides P, Ballew RM, Huson DH, Wortman JR, Zhang Q, Kodira CD, Zheng XH, Chen L, Skupski M, Subramanian G, Thomas PD, Zhang J, Gabor Miklos GL, Nelson C, Broder S, Clark AG, Nadeau J, McKusick VA, Zinder N, Levine AJ, Roberts RJ, Simon M, Slayman C, Hunkapiller M, Bolanos R, Delcher A, Dew I, Fasulo D, Flanigan M, Florea L, Halpern A, Hannenhalli S, Kravitz S, Levy S, Mobarry C, Reinert K, Remington K, Abu-Threideh J, Beasley E, Biddick K, Bonazzi V, Brandon R, Cargill M, Chandramouliswaran I, Charlab R, Chaturvedi K, Deng Z, Di Francesco V, Dunn P, Eilbeck K, Evangelista C, Gabrielian AE, Gan W, Ge W, Gong F, Gu Z, Guan P, Heiman TJ, Higgins ME, Ji RR, Ke Z, Ketchum KA, Lai Z, Lei Y, Li Z, Li J, Liang Y, Lin X, Lu F, Merkulov GV, Milshina N, Moore HM, Naik AK, Narayan VA, Neelam B, Nusskern D, Rusch DB, Salzberg S, Shao W, Shue B, Sun J, Wang Z, Wang A, Wang X, Wang J, Wei M, Wides R, Xiao C, Yan C, Yao A, Ye J, Zhan M, Zhang W, Zhang H, Zhao Q, Zheng L, Zhong F, Zhong W, Zhu S, Zhao S, Gilbert D, Baumhueter S, Spier G, Carter C, Cravchik A, Woodage T, Ali F, An H, Awe A, Baldwin D, Baden H, Barnstead M, Barrow I, Beeson K, Busam D, Carver A, Center A, Cheng ML, Curry L, Danaher S, Davenport L, Desilets R, Dietz S, Dodson K, Doup L, Ferriera S, Garg N, Gluecksmann A, Hart B, Haynes J, Haynes C, Heiner C, Hladun S, Hostin D, Houck J, Howland T, Ibegwam C, Johnson J, Kalush F, Kline L, Koduru S, Love A, Mann F, May D, McCawley S, McIntosh T, McMullen I, Moy M, Moy L, Murphy B, Nelson K, Pfannkoch C, Pratts E, Puri V, Qureshi H, Reardon M, Rodriguez R, Rogers YH, Romblad D, Ruhfel B, Scott R, Sitter C, Smallwood M, Stewart E, Strong R, Suh E, Thomas R, Tint NN, Tse S, Vech C, Wang G, Wetter J, Williams S, Williams M, Windsor S, Winn-Deen E, Wolfe K, Zaveri J, Zaveri K, Abril JF, Guigo R, Campbell MJ, Sjolander KV, Karlak B, Kejariwal A, Mi H, Lazareva B, Hatton T, Narechania A, Diemer K, Muruganujan A, Guo N, Sato S, Bafna V, Istrail S, Lippert R, Schwartz R, Walenz B, Yooseph S, Allen D, Basu A, Baxendale J, Blick L, Caminha M, Carnes-Stine J, Caulk P, Chiang YH, Coyne M, Dahlke C, Mays A, Dombroski M, Donnelly M, Ely D, Esparham S, Fosler C, Gire H, Glanowski S, Glasser K, Glodek A, Gorokhov M, Graham K, Gropman B, Harris M, Heil J, Henderson S, Hoover J, Jennings D, Jordan C, Jordan J, Kasha J, Kagan L, Kraft C, Levitsky A, Lewis M, Liu X, Lopez J, Ma D, Majoros W, McDaniel J, Murphy S, Newman M, Nguyen T, Nguyen N, Nodell M, Pan S, Peck J, Peterson M, Rowe W, Sanders R, Scott J, Simpson M, Smith T, Sprague A, Stockwell T, Turner R, Venter E, Wang M, Wen M, Wu D, Wu M, Xia A, Zandieh A, Zhu X, The sequence of the human genome. Science. 2001 Feb 16;291(5507):1304-51.