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XSB2359 : protein kinase C, beta 1, isoform CRA_a [Rattus norvegicus]

[ CaMP Format ]

This entry is computationally expanded from SB0039

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein Namesprotein kinase C; beta 1; isoform CRA_a
Gene NamesPrkcb1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDM17554 N/A 25023 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 544 aa

Average Mass: 62.447 kDa

Monoisotopic Mass: 62.406 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
C1_1 1. 125-9.40.39
C2 1. 44131128.32.5e-35
--- cleavage 182 ---
--- cleavage 191 ---
Pkinase 1. 213471262.21.2e-75
Pkinase_C 1. 49153655.61.9e-13

3. Sequence Information

Fasta Sequence: XSB2359.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] RQKFERAKIG182-QGTKAPEEKT

Gly182 Gln

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg173Gln174Lys175Phe176Glu177Arg178Ala179Lys180Ile181Gly182
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gln183Gly184Thr185Lys186Ala187Pro188Glu189Glu190Lys191Thr192

Sequence conservation (by blast)

[Site 2] GQGTKAPEEK191-TANTISKFDN

Lys191 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly182Gln183Gly184Thr185Lys186Ala187Pro188Glu189Glu190Lys191
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr192Ala193Asn194Thr195Ile196Ser197Lys198Phe199Asp200Asn201

Sequence conservation (by blast)

* References

[PubMed ID: 15632090] Florea L, Di Francesco V, Miller J, Turner R, Yao A, Harris M, Walenz B, Mobarry C, Merkulov GV, Charlab R, Dew I, Deng Z, Istrail S, Li P, Sutton G, Gene and alternative splicing annotation with AIR. Genome Res. 2005 Jan;15(1):54-66.