logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2360 : protein kinase C, beta 1, isoform CRA_c [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0039

* Basic Information

OrganismMus musculus (house mouse)
Protein Namesprotein kinase C; beta 1; isoform CRA_c
Gene NamesPrkcb1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDL17280 N/A 18751 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 638 aa

Average Mass: 73.235 kDa

Monoisotopic Mass: 73.187 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
C1_1 1. 45680.18.2e-21
C1_1 2. 6912197.35.4e-26
C2 1. 140227128.32.5e-35
--- cleavage 278 ---
--- cleavage 287 ---
Pkinase 1. 309567262.21.2e-75
Pkinase_C 1. 58763371.92.4e-18

3. Sequence Information

Fasta Sequence: XSB2360.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] RQKFERAKIG278-QGTKAPEEKT

Gly278 Gln

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg269Gln270Lys271Phe272Glu273Arg274Ala275Lys276Ile277Gly278
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gln279Gly280Thr281Lys282Ala283Pro284Glu285Glu286Lys287Thr288

Sequence conservation (by blast)

[Site 2] GQGTKAPEEK287-TANTISKFDN

Lys287 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly278Gln279Gly280Thr281Lys282Ala283Pro284Glu285Glu286Lys287
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr288Ala289Asn290Thr291Ile292Ser293Lys294Phe295Asp296Asn297

Sequence conservation (by blast)

* References

[PubMed ID: 12040188] Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD, A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 2002 May 31;296(5573):1661-71.