XSB2376 : solute carrier family 6 (neurotransmitter transporter, glycine), member 5 isoform b [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0013
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Transporter; solute carrier family 6 (neurotransmitter transporter; glycine); member 5 isoform b; glycine transporter 2 |
| Gene Names | Slc6a5; solute carrier family 6 (neurotransmitter transporter, glycine), member 5 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_683733 | NM_148931 | 104245 | B2RQX9_MOUSE | N/A | N/A | N/A | mmu:104245 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 791 aa
Average Mass: 87.029 kDa
Monoisotopic Mass: 86.972 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| TT_ORF2a 1. | 26 | 73 | -2.0 | 6.1 |
| --- cleavage 156 --- | ||||
| --- cleavage 148 --- | ||||
| SNF 1. | 185 | 748 | 1018.6 | 2.4e-303 |
3. Sequence Information
Fasta Sequence: XSB2376.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] NMSQSTVVLG156-TDGIASVLPG
Gly156 
Thr
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn147 | Met148 | Ser149 | Gln150 | Ser151 | Thr152 | Val153 | Val154 | Leu155 | Gly156 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Thr157 | Asp158 | Gly159 | Ile160 | Ala161 | Ser162 | Val163 | Leu164 | Pro165 | Gly166 |
Sequence conservation (by blast)
[Site 2] NTPAVGWVNM148-SQSTVVLGTD
Met148 Ser
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Asn139 | Thr140 | Pro141 | Ala142 | Val143 | Gly144 | Trp145 | Val146 | Asn147 | Met148 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser149 | Gln150 | Ser151 | Thr152 | Val153 | Val154 | Leu155 | Gly156 | Thr157 | Asp158 |
Sequence conservation (by blast)
* References
[PubMed ID: 18634777] Huang M, Huang T, Xiang Y, Xie Z, Chen Y, Yan R, Xu J, Cheng L, Ptf1a, Lbx1 and Pax2 coordinate glycinergic and peptidergic transmitter phenotypes in dorsal spinal inhibitory neurons. Dev Biol. 2008 Oct 15;322(2):394-405. Epub 2008 Jul 2.