logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2379 : solute carrier family 6 (neurotransmitter transporter, glycine), member 5, isoform CRA_a [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0013

* Basic Information

OrganismMus musculus (house mouse)
Protein Namessolute carrier family 6 (neurotransmitter transporter; glycine); member 5; isoform CRA_a
Gene NamesSlc6a5
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDL22979 N/A 104245 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 378 aa

Average Mass: 40.193 kDa

Monoisotopic Mass: 40.167 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
TT_ORF2a 1. 3481-2.36.7
HdeA 1. 133201-32.89.9
--- cleavage 164 (inside HdeA 133..201) ---
--- cleavage 156 (inside HdeA 133..201) ---
DUP 1. 283365-53.49.2

3. Sequence Information

Fasta Sequence: XSB2379.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] NMSQSTVVLG164-TDGIASVLPG

Gly164 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn155Met156Ser157Gln158Ser159Thr160Val161Val162Leu163Gly164
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr165Asp166Gly167Ile168Ala169Ser170Val171Leu172Pro173Gly174

Sequence conservation (by blast)

[Site 2] NTPAVGWVNM156-SQSTVVLGTD

Met156 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn147Thr148Pro149Ala150Val151Gly152Trp153Val154Asn155Met156
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser157Gln158Ser159Thr160Val161Val162Leu163Gly164Thr165Asp166

Sequence conservation (by blast)

* References

[PubMed ID: 12040188] Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD, A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 2002 May 31;296(5573):1661-71.