logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2380 : solute carrier family 6 (neurotransmitter transporter, glycine), member 5, isoform CRA_b [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0013

* Basic Information

OrganismMus musculus (house mouse)
Protein Namessolute carrier family 6 (neurotransmitter transporter; glycine); member 5; isoform CRA_b
Gene NamesSlc6a5
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDL22980 N/A 104245 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 370 aa

Average Mass: 39.331 kDa

Monoisotopic Mass: 39.306 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
TT_ORF2a 1. 2673-2.36.7
HdeA 1. 125193-32.89.9
--- cleavage 156 (inside HdeA 125..193) ---
--- cleavage 148 (inside HdeA 125..193) ---
DUP 1. 275357-53.49.2

3. Sequence Information

Fasta Sequence: XSB2380.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

2 [sites]

Cleavage sites (±10aa)

[Site 1] NMSQSTVVLG156-TDGIASVLPG

Gly156 Thr

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn147Met148Ser149Gln150Ser151Thr152Val153Val154Leu155Gly156
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Thr157Asp158Gly159Ile160Ala161Ser162Val163Leu164Pro165Gly166

Sequence conservation (by blast)

[Site 2] NTPAVGWVNM148-SQSTVVLGTD

Met148 Ser

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Asn139Thr140Pro141Ala142Val143Gly144Trp145Val146Asn147Met148
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ser149Gln150Ser151Thr152Val153Val154Leu155Gly156Thr157Asp158

Sequence conservation (by blast)

* References

[PubMed ID: 12040188] Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD, A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 2002 May 31;296(5573):1661-71.