logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2438 : actin 2 [Brugia malayi]

[ CaMP Format ]

This entry is computationally expanded from SB0031

* Basic Information

OrganismBrugia malayi
Protein NamesActin 2, putative; actin 2
Gene NamesBm1_21725
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
XP_001895799 XM_001895764 6099246 A8PC57_BRUMA N/A N/A N/A bmy:Bm1_21725

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 376 aa

Average Mass: 41.805 kDa

Monoisotopic Mass: 41.778 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 3376836.41.7e-248
--- cleavage 38 (inside Actin 3..376) ---

3. Sequence Information

Fasta Sequence: XSB2438.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR38-PRHQGVMVGM

Arg38 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg29Ala30Val31Phe32Pro33Ser34Ile35Val36Gly37Arg38
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro39Arg40His41Gln42Gly43Val44Met45Val46Gly47Met48

Sequence conservation (by blast)

* References

[PubMed ID: 17885136] Ghedin E, Wang S, Spiro D, Caler E, Zhao Q, Crabtree J, Allen JE, Delcher AL, Guiliano DB, Miranda-Saavedra D, Angiuoli SV, Creasy T, Amedeo P, Haas B, El-Sayed NM, Wortman JR, Feldblyum T, Tallon L, Schatz M, Shumway M, Koo H, Salzberg SL, Schobel S, Pertea M, Pop M, White O, Barton GJ, Carlow CK, Crawford MJ, Daub J, Dimmic MW, Estes CF, Foster JM, Ganatra M, Gregory WF, Johnson NM, Jin J, Komuniecki R, Korf I, Kumar S, Laney S, Li BW, Li W, Lindblom TH, Lustigman S, Ma D, Maina CV, Martin DM, McCarter JP, McReynolds L, Mitreva M, Nutman TB, Parkinson J, Peregrin-Alvarez JM, Poole C, Ren Q, Saunders L, Sluder AE, Smith K, Stanke M, Unnasch TR, Ware J, Wei AD, Weil G, Williams DJ, Zhang Y, Williams SA, Fraser-Liggett C, Slatko B, Blaxter ML, Scott AL, Draft genome of the filarial nematode parasite Brugia malayi. Science. 2007 Sep 21;317(5845):1756-60.