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XSB2440 : Chain A, The Structure Of Crystalline Profilin-Beta-Actin

[ CaMP Format ]

This entry is computationally expanded from SB0031

* Basic Information

OrganismBos taurus (cattle)
Protein NamesActin, cytoplasmic 1; Beta-actin; Actin, cytoplasmic 1, N-terminally processed
Gene NamesACTB
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
2BTF_A N/A N/A ACTB_BOVIN N/A N/A N/A bta:280979

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 374 aa

Average Mass: 41.606 kDa

Monoisotopic Mass: 41.579 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Actin 1. 1374830.78.6e-247
--- cleavage 36 (inside Actin 1..374) ---

3. Sequence Information

Fasta Sequence: XSB2440.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1HLU (X-ray; 265 A; A=2-375), 2BTF (X-ray; 255 A; A=2-375), 2OAN (X-ray; 261 A; A/B/C/D=1-375)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] RAVFPSIVGR36-PRHQGVMVGM

Arg36 Pro

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Arg27Ala28Val29Phe30Pro31Ser32Ile33Val34Gly35Arg36
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Pro37Arg38His39Gln40Gly41Val42Met43Val44Gly45Met46

Sequence conservation (by blast)

* References

[PubMed ID: 2585507] Schutt CE, Lindberg U, Myslik J, Strauss N, Molecular packing in profilin: actin crystals and its implications. J Mol Biol. 1989 Oct 20;209(4):735-46.

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