XSB2669 : calpain 2 [Mus musculus]
[ CaMP Format ]
This entry is computationally expanded from SB0001
* Basic Information
| Organism | Mus musculus (house mouse) |
| Protein Names | Calpain-2 catalytic subunit; 3.4.22.53; Calpain-2 large subunit; Calcium-activated neutral proteinase 2; CANP 2; Calpain M-type; M-calpain; Millimolar-calpain; 80 kDa M-calpain subunit; CALP80; calpain 2; cysteine proteinase; m-calpain 80 kDa large subunit; m-calpain large subunit |
| Gene Names | Capn2; calpain 2 |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| NP_033924 | NM_009794 | 12334 | CAN2_MOUSE | N/A | N/A | N/A | mmu:12334 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 700 aa
Average Mass: 79.872 kDa
Monoisotopic Mass: 79.822 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 19 --- | ||||
| --- cleavage 9 --- | ||||
| Peptidase_C2 1. | 45 | 344 | 810.8 | 8.5e-241 |
| Calpain_III 1. | 355 | 510 | 384.7 | 1.6e-112 |
| efhand 1. | 576 | 604 | 20.4 | 0.0074 |
| efhand 2. | 606 | 634 | 19.4 | 0.015 |
| efhand 3. | 671 | 698 | 1.8 | 13 |
3. Sequence Information
Fasta Sequence: XSB2669.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] KDREAAEGLG19-SHERAIKYLN
Gly19 
Ser
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Lys10 | Asp11 | Arg12 | Glu13 | Ala14 | Ala15 | Glu16 | Gly17 | Leu18 | Gly19 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ser20 | His21 | Glu22 | Arg23 | Ala24 | Ile25 | Lys26 | Tyr27 | Leu28 | Asn29 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MAGIAIKLAKDREAAEGLGSHERAIKYLNQDYETLRNECLEAGALFQDP |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 100.00 | 20 | unnamed protein product |
| 2 | N/A | 100.00 | 14 | C |
| 3 | Rattus norvegicus | 99.80 | 9 | calpain 2 |
| 4 | Homo sapiens | 95.50 | 25 | calpain 2, large subunit |
| 5 | catalytic | 95.50 | 1 | Calpain 2, large |
| 6 | Macaca mulatta | 94.00 | 3 | PREDICTED: calpain 2, large subunit |
| 7 | Bos taurus | 92.40 | 7 | Unknown (protein for MGC:138930) |
| 8 | Monodelphis domestica | 80.10 | 2 | PREDICTED: similar to calpain 2 |
| 9 | Xenopus laevis | 69.70 | 10 | hypothetical protein LOC399075 |
| 10 | Gallus gallus | 68.90 | 5 | calpain 1, (mu/I) large subunit |
| 11 | Coturnix coturnix | 68.20 | 1 | quail calpain |
| 12 | Xenopus tropicalis | 67.80 | 6 | calpain 2, (m/II) large subunit |
| 13 | Canis familiaris | 67.40 | 6 | PREDICTED: similar to calpain 8 |
| 14 | Danio rerio | 64.30 | 31 | hypothetical protein LOC550505 |
| 15 | Tetraodon nigroviridis | 60.10 | 7 | unnamed protein product |
| 16 | Oncorhynchus mykiss | 60.10 | 3 | m-calpain |
| 17 | Pan troglodytes | 59.70 | 6 | PREDICTED: similar to calpain, partial |
| 18 | Stizostedion vitreum vitreum | 59.70 | 1 | putative calpain-like protein |
| 19 | Pongo pygmaeus | 55.80 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 20 | synthetic construct | 55.80 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 21 | Sus scrofa | 55.10 | 3 | micromolar calcium-activated neutral protease 1 is |
| 22 | Macaca fascicularis | 40.80 | 1 | unnamed protein product |
| 23 | Bos grunniens | 35.40 | 1 | micromolar calcium-activated neutral protease 1 la |
| 24 | Drosophila melanogaster | 35.00 | 6 | CAA55297.1 |
| 25 | Aedes aegypti | 35.00 | 1 | calpain, putative |
| 26 | Oryctolagus cuniculus | 34.70 | 1 | calpain 3, (p94) |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| N/A | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||||||||||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| Rattus norvegicus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |||||+|||||||||||||#|||||||||||||||||||||||||||||| Sbjct 1 MAGIAMKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |
| Homo sapiens | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 1 MAGIAAKLAKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 49 |
| catalytic | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 30 MAGIAAKLAKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 78 |
| Macaca mulatta | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| || ||||||||||#|||||||||||||| ||||||||| ||||| Sbjct 1 MAGIAAKLVKDREAAEGLG#SHERAIKYLNQDYEALRNECLEAGTLFQDP 49 |
| Bos taurus | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||||| |||||||||||||#|||||+||||||| ||+|||||||||||| Sbjct 1 MAGIAAKLAKDREAAEGLG#SHERAVKYLNQDYAALRDECLEAGALFQDP 49 |
| Monodelphis domestica | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+||| |+ +||||| |||#+||+|+|||||||||| +|||| | ||||| Sbjct 1 MSGIAAKVVRDREAAAGLG#THEQAVKYLNQDYETLLSECLEEGKLFQDP 49 |
| Xenopus laevis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+|+| +|||+| | | |#++|+|+ |||||+| ||||||++|+||+|| Sbjct 1 MSGVADRLAKERARASGFG#TNEKALPYLNQDFEALRNECLQSGSLFKDP 49 |
| Gallus gallus | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||| +| +|| |||+|# | |+|||||||| |+ ||+|+| ||+|| Sbjct 6 GIAARLQRDRLRAEGVG#EHNNAVKYLNQDYEALKQECIESGTLFRDP 52 |
| Coturnix coturnix | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 ||| +| +|| |||+|# | |+|||||||| |+ |+|+||||+|| Sbjct 6 GIAARLQRDRLRAEGVG#EHNNAVKYLNQDYEALKQACIESGALFRDP 52 |
| Xenopus tropicalis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+|+| +|||+| | |||#++|+|+ ||+|||| ||||||++| ||+| Sbjct 1 MSGVADRLAKERALASGLG#TNEKALPYLSQDYEALRNECLQSGTLFKD 48 |
| Canis familiaris | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+ +| ++|| + || |||#||++|+||| ||+| || +||+|| ||+|| Sbjct 94 MSALAARIAKQQAAAGGLG#SHQKAVKYLGQDFEKLRQQCLDAGVLFKDP 142 |
| Danio rerio | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| || |+| | |+|#++ +| |+|||||| |+ ||||+| |||| Sbjct 1 MSGIATKLQKNRARAAGIG#TNAQAAKFLNQDYEALKRECLESGRLFQD 48 |
| Tetraodon nigroviridis | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| || |+ |+| |#+ +| ||||||+|+|| ||| | |||| Sbjct 1 MSGIAAKLQHHRDRAQGFG#TASQAQKYLNQDFESLRESCLERGELFQD 48 |
| Oncorhynchus mykiss | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+|+| ||| | | | |#++ |+||||||+| || +|| | || || Sbjct 1 MSGMASNLAKKRALAAGFG#TNANAVKYLNQDFEALRAQCLNRGGLFSDP 49 |
| Pan troglodytes | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 || | +++ | | +|||#|++ |+||| ||++||| +||++| ||+|| Sbjct 1 MAAQAAGVSRQRAATQGLG#SNQNALKYLGQDFKTLRQQCLDSGVLFKDP 49 |
| Stizostedion vitreum vitreum | Query 1 MAGIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |+||| | + || +|+|#| +|+|||||||| || |||+ +||+| Sbjct 1 MSGIAATLQRRREKEQGIG#SCSQAVKYLNQDYEALRRRCLESESLFKD 48 |
| Pongo pygmaeus | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++| ||+| Sbjct 13 GVSAQVQKQRARELGLG#RHENAIKYLGQDYEQLRVRCLQSGTLFRD 58 |
| synthetic construct | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++| ||+| Sbjct 13 GVSAQVQKQRARELGLG#RHENAIKYLGQDYEQLRVRCLQSGTLFRD 58 |
| Sus scrofa | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 |++ ++ | | |||# || ||||| |||| || ||++|+||+| Sbjct 13 GVSAQVQKLRAKELGLG#RHENAIKYLGQDYEQLRAHCLQSGSLFRD 58 |
| Macaca fascicularis | Query 3 GIAIKLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQDP 49 |+ + | | |+|# | | + || +| || || | ||+|| Sbjct 36 GMVAHINYSRLKASGVG#QHHNAHNFGNQSFEELRAVCLRKGELFEDP 82 |
| Bos grunniens | Query 27 YLNQDYETLRNECLEAGALFQD 48 || |||| || ||+ ||||+| Sbjct 1 YLGQDYEQLRVHCLQRGALFRD 22 |
| Drosophila melanogaster | Query 30 QDYETLRNECLEAGALFQDP 49 |||||+ | || +|+||+|| Sbjct 50 QDYETILNSCLASGSLFEDP 69 |
| Aedes aegypti | Query 30 QDYETLRNECLEAGALFQDP 49 ||| ||++|||+|+||+|| Sbjct 115 QDYYVLRSQCLESGSLFEDP 134 |
| Oryctolagus cuniculus | Query 7 KLAKDREAAEGLG#SHERAIKYLNQDYETLRNECLEAGALFQD 48 ++ ++|+ | |#+ + ||| ||+ || || ||+| Sbjct 12 RVIRERDRRNGEG#TVTQPIKYEGQDFVVLRQRCLAQKCLFED 53 |
[Site 2] MAGIAIKLA9-KDREAAEGLG
Ala9 Lys
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| - | Met1 | Ala2 | Gly3 | Ile4 | Ala5 | Ile6 | Lys7 | Leu8 | Ala9 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Lys10 | Asp11 | Arg12 | Glu13 | Ala14 | Ala15 | Glu16 | Gly17 | Leu18 | Gly19 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| MAGIAIKLAKDREAAEGLGSHERAIKYLNQDYETLRNEC |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | Mus musculus | 81.30 | 15 | unnamed protein product |
| 2 | N/A | 81.30 | 12 | C |
| 3 | Rattus norvegicus | 80.10 | 5 | calpain 2 |
| 4 | Homo sapiens | 77.40 | 17 | AF261089_1 calpain large polypeptide L2 |
| 5 | catalytic | 77.40 | 1 | Calpain 2, large |
| 6 | Macaca mulatta | 75.90 | 3 | PREDICTED: calpain 2, large subunit |
| 7 | Bos taurus | 72.80 | 6 | Unknown (protein for MGC:138930) |
| 8 | Monodelphis domestica | 64.30 | 2 | PREDICTED: similar to calpain 2 |
| 9 | Xenopus tropicalis | 56.20 | 5 | calpain 2, (m/II) large subunit |
| 10 | Xenopus laevis | 55.10 | 9 | hypothetical protein LOC399075 |
| 11 | Gallus gallus | 54.70 | 5 | PREDICTED: similar to calpain 8 (nCL-2) |
| 12 | Canis familiaris | 52.00 | 3 | PREDICTED: similar to calpain 8 |
| 13 | Coturnix coturnix | 52.00 | 1 | quail calpain |
| 14 | Danio rerio | 50.80 | 23 | hypothetical protein LOC445091 |
| 15 | Oncorhynchus mykiss | 50.10 | 3 | calpain 2 catalytic subunit |
| 16 | Stizostedion vitreum vitreum | 49.70 | 1 | putative calpain-like protein |
| 17 | Tetraodon nigroviridis | 47.00 | 6 | unnamed protein product |
| 18 | Pan troglodytes | 45.40 | 5 | PREDICTED: similar to calpain, partial |
| 19 | Pongo pygmaeus | 44.30 | 1 | CAN1_PONPY Calpain-1 catalytic subunit (Calpain-1 |
| 20 | synthetic construct | 44.30 | 1 | Homo sapiens calpain 1, (mu/I) large subunit |
| 21 | Sus scrofa | 43.10 | 2 | micromolar calcium-activated neutral protease 1 is |
Top-ranked sequences
| organism | matching |
|---|---|
| Mus musculus | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |
| N/A | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |||||||||#|||||||||||||||||||||||||||||| Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |
| Rattus norvegicus | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |||||+|||#|||||||||||||||||||||||||||||| Sbjct 1 MAGIAMKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |
| Homo sapiens | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 ||||| |||#|||||||||||||||||||||||| ||||| Sbjct 1 MAGIAAKLA#KDREAAEGLGSHERAIKYLNQDYEALRNEC 39 |
| catalytic | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 ||||| |||#|||||||||||||||||||||||| ||||| Sbjct 30 MAGIAAKLA#KDREAAEGLGSHERAIKYLNQDYEALRNEC 68 |
| Macaca mulatta | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 ||||| || #|||||||||||||||||||||||| ||||| Sbjct 1 MAGIAAKLV#KDREAAEGLGSHERAIKYLNQDYEALRNEC 39 |
| Bos taurus | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 ||||| |||#|||||||||||||||+||||||| ||+|| Sbjct 1 MAGIAAKLA#KDREAAEGLGSHERAVKYLNQDYAALRDEC 39 |
| Monodelphis domestica | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+||| |+ #+||||| |||+||+|+|||||||||| +|| Sbjct 1 MSGIAAKVV#RDREAAAGLGTHEQAVKYLNQDYETLLSEC 39 |
| Xenopus tropicalis | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+|+| +||#|+| | |||++|+|+ ||+|||| ||||| Sbjct 1 MSGVADRLA#KERALASGLGTNEKALPYLSQDYEALRNEC 39 |
| Xenopus laevis | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+|+| +||#|+| | | |++|+|+ |||||+| ||||| Sbjct 1 MSGVADRLA#KERARASGFGTNEKALPYLNQDFEALRNEC 39 |
| Gallus gallus | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |||+| +| #++| |||||||+ +|| || |||| || | Sbjct 1 MAGLAARLC#QERAAAEGLGSYRKAISYLGQDYEALRQRC 39 |
| Canis familiaris | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+ +| ++|#| + || |||||++|+||| ||+| || +| Sbjct 94 MSALAARIA#KQQAAAGGLGSHQKAVKYLGQDFEKLRQQC 132 |
| Coturnix coturnix | Query 3 GIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 ||| +| #+|| |||+| | |+|||||||| |+ | Sbjct 6 GIAARLQ#RDRLRAEGVGEHNNAVKYLNQDYEALKQAC 42 |
| Danio rerio | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+|||||| # | | |+|++ +|+|+|||||| |+ || Sbjct 1 MSGIAIKLQ#HKRAQAAGIGTNAQAVKFLNQDYEALKREC 39 |
| Oncorhynchus mykiss | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |||+| ||#| | | | |++ | ||||||+|+||+|| Sbjct 1 MAGVASTLA#KKRALAAGFGTNANASKYLNQDFESLRSEC 39 |
| Stizostedion vitreum vitreum | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+||| | #+ || +|+|| +|+|||||||| || | Sbjct 1 MSGIAATLQ#RRREKEQGIGSCSQAVKYLNQDYEALRRRC 39 |
| Tetraodon nigroviridis | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |+||| || # |+ |+| |+ +| ||||||+|+|| | Sbjct 1 MSGIAAKLQ#HHRDRAQGFGTASQAQKYLNQDFESLRESC 39 |
| Pan troglodytes | Query 1 MAGIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 || | ++#+ | | +||||++ |+||| ||++||| +| Sbjct 1 MAAQAAGVS#RQRAATQGLGSNQNALKYLGQDFKTLRQQC 39 |
| Pongo pygmaeus | Query 3 GIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |++ ++ #| | ||| || ||||| |||| || | Sbjct 13 GVSAQVQ#KQRARELGLGRHENAIKYLGQDYEQLRVRC 49 |
| synthetic construct | Query 3 GIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |++ ++ #| | ||| || ||||| |||| || | Sbjct 13 GVSAQVQ#KQRARELGLGRHENAIKYLGQDYEQLRVRC 49 |
| Sus scrofa | Query 3 GIAIKLA#KDREAAEGLGSHERAIKYLNQDYETLRNEC 39 |++ ++ #| | ||| || ||||| |||| || | Sbjct 13 GVSAQVQ#KLRAKELGLGRHENAIKYLGQDYEQLRAHC 49 |
* References
[PubMed ID: 18840650] Undyala VV, Dembo M, Cembrola K, Perrin BJ, Huttenlocher A, Elce JS, Greer PA, Wang YL, Beningo KA, The calpain small subunit regulates cell-substrate mechanical interactions during fibroblast migration. J Cell Sci. 2008 Nov 1;121(Pt 21):3581-8. Epub 2008 Oct 7.
[PubMed ID: 18216163] ... Honda M, Masui F, Kanzawa N, Tsuchiya T, Toyo-oka T, Specific knockdown of m-calpain blocks myogenesis with cDNA deduced from the corresponding RNAi. Am J Physiol Cell Physiol. 2008 Apr;294(4):C957-65. Epub 2008 Jan 23.
[PubMed ID: 18415939] ... Raynaud F, Marcilhac A, Chebli K, Benyamin Y, Rossel M, Calpain 2 expression pattern and sub-cellular localization during mouse embryogenesis. Int J Dev Biol. 2008;52(4):383-8.
[PubMed ID: 17640526] ... Chen F, Qian L, Yang ZH, Huang Y, Ngo ST, Ruan NJ, Wang J, Schneider C, Noakes PG, Ding YQ, Mei L, Luo ZG, Rapsyn interaction with calpain stabilizes AChR clusters at the neuromuscular junction. Neuron. 2007 Jul 19;55(2):247-60.
[PubMed ID: 17541403] ... Wu Y, Liang S, Oda Y, Ohmori I, Nishiki T, Takei K, Matsui H, Tomizawa K, Truncations of amphiphysin I by calpain inhibit vesicle endocytosis during neural hyperexcitation. EMBO J. 2007 Jun 20;26(12):2981-90. Epub 2007 May 31.
[PubMed ID: 9396712] ... Sorimachi H, Ishiura S, Suzuki K, Structure and physiological function of calpains. Biochem J. 1997 Dec 15;328 ( Pt 3):721-32.
[PubMed ID: 9339374] ... Dear N, Matena K, Vingron M, Boehm T, A new subfamily of vertebrate calpains lacking a calmodulin-like domain: implications for calpain regulation and evolution. Genomics. 1997 Oct 1;45(1):175-84.
[PubMed ID: 8806430] ... Spencer MJ, Tidball JG, Calpain translocation during muscle fiber necrosis and regeneration in dystrophin-deficient mice. Exp Cell Res. 1996 Aug 1;226(2):264-72.
[PubMed ID: 8738748] ... Li J, Grynspan F, Berman S, Nixon R, Bursztajn S, Regional differences in gene expression for calcium activated neutral proteases (calpains) and their endogenous inhibitor calpastatin in mouse brain and spinal cord. J Neurobiol. 1996 Jun;30(2):177-91.
[PubMed ID: 2209092] ... Ohno S, Minoshima S, Kudoh J, Fukuyama R, Shimizu Y, Ohmi-Imajoh S, Shimizu N, Suzuki K, Four genes for the calpain family locate on four distinct human chromosomes. Cytogenet Cell Genet. 1990;53(4):225-9.