XSB2828 : unnamed protein product [Homo sapiens]
[ CaMP Format ]
This entry is computationally expanded from SB0070
* Basic Information
| Organism | Homo sapiens (human) |
| Protein Names | cDNA FLJ52130, highly similar to Insulin-like growth factor-binding protein 4 |
| Gene Names | Not available |
| Gene Locus | Not available |
| GO Function | Not available |
| Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
|---|---|---|---|---|---|---|---|
| BAG65363 | N/A | N/A | B4E351_HUMAN | N/A | N/A | N/A | hsa: |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 158 aa
Average Mass: 17.635 kDa
Monoisotopic Mass: 17.624 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
|---|---|---|---|---|
| --- cleavage 43 --- | ||||
| --- cleavage 59 --- | ||||
| Thyroglobulin_1 1. | 74 | 149 | 144.0 | 4.7e-40 |
3. Sequence Information
Fasta Sequence: XSB2828.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] HDRRCLQKHF43-AKIRDRSTSG
Phe43 
Ala
 |
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| His34 | Asp35 | Arg36 | Arg37 | Cys38 | Leu39 | Gln40 | Lys41 | His42 | Phe43 |
 |
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Ala44 | Lys45 | Ile46 | Arg47 | Asp48 | Arg49 | Ser50 | Thr51 | Ser52 | Gly53 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| QPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGS |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 131.00 | 2 | - |
| 2 | Homo sapiens | 131.00 | 2 | insulin-like growth factor binding protein 4 precu |
| 3 | synthetic construct | 131.00 | 2 | insulin-like growth factor binding protein 4 |
| 4 | Pan troglodytes | 131.00 | 1 | PREDICTED: similar to Insulin-like growth factor-b |
| 5 | Canis familiaris | 125.00 | 1 | PREDICTED: similar to Insulin-like growth factor b |
| 6 | Equus caballus | 125.00 | 1 | insulin-like growth factor binding protein-4 |
| 7 | Bos taurus | 123.00 | 2 | insulin-like growth factor binding protein 4 |
| 8 | Ovis aries | 121.00 | 1 | IBP4_SHEEP Insulin-like growth factor-binding prot |
| 9 | Sus scrofa | 119.00 | 1 | IBP4 |
| 10 | Mus musculus | 96.70 | 3 | unnamed protein product |
| 11 | Rattus norvegicus | 96.70 | 2 | insulin-like growth factor binding protein 4 |
| 12 | Monodelphis domestica | 82.80 | 1 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 13 | Gallus gallus | 75.10 | 1 | insulin-like growth factor binding protein 4 |
| 14 | Bubalus bubalis | 70.90 | 1 | insulin-like growth factor binding protein-4 |
| 15 | Oncorhynchus mykiss | 36.60 | 1 | insulin-like growth factor binding protein 4 |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |
| Homo sapiens | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |
| synthetic construct | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |
| Pan troglodytes | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |
| Canis familiaris | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#||||||||||||||| | |||+|||||||| Sbjct 307 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVIGVPREEARPVPQGS 366 |
| Equus caballus | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||||||||||||||#||||||||||||||| | |||+|||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 152 |
| Bos taurus | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |
| Ovis aries | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 |||||||||||||||||||||||+||||| #||||||||||||||| |||||+ ||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEVRPVPQGS 152 |
| Sus scrofa | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||||||||||||||||| |||||||| #||||||||||||||| |||||+|||||||| Sbjct 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 |
| Mus musculus | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 | ||||| +||||||+|||||| |||||| #||||||| |||+ | |||+ ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKIRDRS----KMKIVGTPREEPRPVPQGS 169 |
| Rattus norvegicus | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 | ||||| +||||||+|||||| |||||| #||+|||| |||| | |||+ ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKVRDRS----KMKVVGTPREEPRPVPQGS 169 |
| Monodelphis domestica | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNG--APREDARPVPQ 71 | ++|+| +||||||||||+|||+|+||| #|||| |++ |||| | | ||| ||+ | Sbjct 114 QTTEKEESEHPNNSFSPCSSHDRKCMQKHS#AKIRVVSSNSGKMKSIGSSAHREDTRPMAQ 173 Query 72 GS 73 || Query 72 GS 73 |
| Gallus gallus | Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAP--REDARPVPQ 71 || +|+| +|||||||||| |||+|||| #|| | +| ||+ +|+| ||++||+ | Sbjct 119 QPPEKEEIEHPNNSFSPCSIHDRKCLQKQQ#AK---RINNGNKMRSSGSPHHREESRPIAQ 175 Query 72 GS 73 || Query 72 GS 73 |
| Bubalus bubalis | Query 38 CLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 73 ||||| #||||||||||||||| |||||+|||||||| Sbjct 1 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 36 |
| Oncorhynchus mykiss | Query 17 DKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDAR 67 |+ +||||| || |+||+|| #|+ +||+ + | | ||| + Sbjct 5 DETIPEHPNNSNIRCSPQDKRCIQKTL#ARHPAKSTN---QRSNNA-REDPK 51 |
[Site 2] STSGGKMKVN59-GAPREDARPV
Asn59 Gly
|
|||||||||
| P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
|---|---|---|---|---|---|---|---|---|---|
| Ser50 | Thr51 | Ser52 | Gly53 | Gly54 | Lys55 | Met56 | Lys57 | Val58 | Asn59 |
|
|||||||||
| P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
| Gly60 | Ala61 | Pro62 | Arg63 | Glu64 | Asp65 | Ala66 | Arg67 | Pro68 | Val69 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
| PCSAHDRRCLQKHFAKIRDRSTSGGKMKVNGAPREDARPVPQGSCQSELHRALERLAASQ |
Summary
| # | organism | max score | hits | top seq |
|---|---|---|---|---|
| 1 | N/A | 127.00 | 3 | - |
| 2 | Homo sapiens | 127.00 | 2 | insulin-like growth factor binding protein 4 precu |
| 3 | synthetic construct | 127.00 | 2 | insulin-like growth factor binding protein 4 |
| 4 | Pan troglodytes | 127.00 | 1 | PREDICTED: similar to Insulin-like growth factor-b |
| 5 | Canis familiaris | 120.00 | 1 | PREDICTED: similar to Insulin-like growth factor b |
| 6 | Equus caballus | 120.00 | 1 | insulin-like growth factor binding protein-4 |
| 7 | Bos taurus | 118.00 | 2 | insulin-like growth factor-binding protein 4 |
| 8 | Ovis aries | 117.00 | 1 | IBP4_SHEEP Insulin-like growth factor-binding prot |
| 9 | Sus scrofa | 114.00 | 1 | IBP4 |
| 10 | Bubalus bubalis | 101.00 | 1 | insulin-like growth factor binding protein-4 |
| 11 | Mus musculus | 100.00 | 3 | insulin-like growth factor binding protein 4 |
| 12 | Rattus norvegicus | 100.00 | 1 | insulin-like growth factor binding protein 4 |
| 13 | Monodelphis domestica | 87.80 | 1 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 14 | Gallus gallus | 80.90 | 1 | insulin-like growth factor binding protein 4 |
| 15 | Tetraodon nigroviridis | 40.00 | 1 | unnamed protein product |
| 16 | Oncorhynchus mykiss | 37.70 | 1 | insulin-like growth factor binding protein 4 |
Top-ranked sequences
| organism | matching |
|---|---|
| N/A | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |
| Homo sapiens | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |
| synthetic construct | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |
| Pan troglodytes | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |
| Canis familiaris | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||| #| |||+|||||||||||||||||||||||| Sbjct 323 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVI#GVPREEARPVPQGSCQSELHRALERLAASQ 382 |
| Equus caballus | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||||||||||||||||||||||||||| #| |||+|||||||||||||||||||||||| Sbjct 109 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 168 |
| Bos taurus | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |||||||+||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 13 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 72 |
| Ovis aries | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |||||||+||||| ||||||||||||||| #|||||+ ||||||||||||||||||||||| Sbjct 109 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEVRPVPQGSCQSELHRALERLAASQ 168 |
| Sus scrofa | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||| |||||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 |
| Bubalus bubalis | Query 38 CLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 ||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 1 CLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 52 |
| Mus musculus | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |||||| |||||| ||||||| |||+ #| |||+ ||||||||||||||||||||||| Sbjct 130 PCSAHDHRCLQKHMAKIRDRS----KMKIV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185 |
| Rattus norvegicus | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 89 |||||| |||||| ||+|||| |||| #| |||+ ||||||||||||||||||||||| Sbjct 130 PCSAHDHRCLQKHMAKVRDRS----KMKVV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185 |
| Monodelphis domestica | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#G--APREDARPVPQGSCQSELHRALERLAA 87 |||+|||+|+||| |||| |++ |||| #| | ||| ||+ ||||||||||||||| | Sbjct 130 PCSSHDRKCMQKHSAKIRVVSSNSGKMKSI#GSSAHREDTRPMAQGSCQSELHRALERLGA 189 Query 88 SQ 89 || Query 88 SQ 89 |
| Gallus gallus | Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAP--REDARPVPQGSCQSELHRALERLAA 87 ||| |||+|||| || | +| ||+ +#|+| ||++||+ ||||||||||||||||| Sbjct 135 PCSIHDRKCLQKQQAK---RINNGNKMRSS#GSPHHREESRPIAQGSCQSELHRALERLAA 191 Query 88 SQ 89 || Query 88 SQ 89 |
| Tetraodon nigroviridis | Query 31 CSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAAS 88 || |+||+|| |+ +||+ + +# + ||+ + | |++|| |||+|||++ Sbjct 139 CSQQDKRCIQKTLARHLSKSTN----QRS#NSGREETKAV-LAPCRAELQRALDRLASN 191 |
| Oncorhynchus mykiss | Query 31 CSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAAS 88 || |+||+|| |+ +||+ + |# | ||| + |++|| |||+|| ++ Sbjct 19 CSPQDKRCIQKTLARHPAKSTN---QRSN#NA-REDPK-AALAPCRAELQRALDRLVSN 71 |
* References
None.