XSB2830 : PREDICTED: similar to Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP-4) (IGF-binding protein 4) [Equus caballus]
[ CaMP Format ]
This entry is computationally expanded from SB0070
* Basic Information
| Organism | Equus caballus (horse) |
| Protein Names | similar to Insulin-like growth factor-binding protein 4 precursor (IGFBP-4) (IBP-4) (IGF-binding protein 4) |
| Gene Names | LOC100067711; Derived by automated computational analysis using gene prediction method: GNOMON. Supporting evidence includes similarity to: 2 mRNAs |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 158 aa
Average Mass: 17.689 kDa
Monoisotopic Mass: 17.678 kDa
2. Domain Information
Annotated Domains: Not Available.
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| --- cleavage 43 --- |
| --- cleavage 59 --- |
| Thyroglobulin_1 1. | 74 | 149 | 144.0 | 4.7e-40 |
3. Sequence Information
Fasta Sequence: XSB2830.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
2 [sites]
Cleavage sites (±10aa)
[Site 1] HDRRCLQKHF43-AKIRDRSTSG
Phe43 
Ala
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| His34 | Asp35 | Arg36 | Arg37 | Cys38 | Leu39 | Gln40 | Lys41 | His42 | Phe43 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ala44 | Lys45 | Ile46 | Arg47 | Asp48 | Arg49 | Ser50 | Thr51 | Ser52 | Gly53 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
QPSDKDEGDHPNNSFSPCSAHDRRCLQKHFAKIRDRSTSGGKMKVVGVPREEARPVPQGS
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Canis familiaris |
130.00 |
1 |
PREDICTED: similar to Insulin-like growth factor b |
| 2 |
Equus caballus |
130.00 |
1 |
insulin-like growth factor binding protein-4 |
| 3 |
N/A |
125.00 |
2 |
- |
| 4 |
Homo sapiens |
125.00 |
2 |
insulin-like growth factor binding protein 4 precu |
| 5 |
Bos taurus |
125.00 |
2 |
insulin-like growth factor binding protein 4 |
| 6 |
synthetic construct |
125.00 |
2 |
insulin-like growth factor binding protein 4 |
| 7 |
Pan troglodytes |
125.00 |
1 |
PREDICTED: similar to Insulin-like growth factor-b |
| 8 |
Ovis aries |
123.00 |
1 |
IBP4_SHEEP Insulin-like growth factor-binding prot |
| 9 |
Sus scrofa |
121.00 |
1 |
IBP4 |
| 10 |
Mus musculus |
100.00 |
3 |
insulin-like growth factor binding protein 4 |
| 11 |
Rattus norvegicus |
100.00 |
2 |
insulin-like growth factor binding protein 4 |
| 12 |
Monodelphis domestica |
82.00 |
1 |
PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 13 |
Gallus gallus |
73.90 |
1 |
insulin-like growth factor binding protein 4 |
| 14 |
Bubalus bubalis |
72.80 |
1 |
insulin-like growth factor binding protein-4 |
| 15 |
Tetraodon nigroviridis |
36.60 |
1 |
unnamed protein product |
Top-ranked sequences
| organism | matching |
|---|
| Canis familiaris |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#|||||||||||||||+||||||||||||||
Sbjct 307 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVIGVPREEARPVPQGS 366
|
| Equus caballus |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
|
| N/A |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#||||||||||||||| | |||+||||||||
Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173
|
| Homo sapiens |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#||||||||||||||| | |||+||||||||
Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173
|
| Bos taurus |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
|||||||||||||||||||||||+||||| #|||||||||||||||+| ||||||||||||
Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173
|
| synthetic construct |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#||||||||||||||| | |||+||||||||
Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173
|
| Pan troglodytes |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||||||||||||||#||||||||||||||| | |||+||||||||
Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173
|
| Ovis aries |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
|||||||||||||||||||||||+||||| #|||||||||||||||+| |||| |||||||
Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEVRPVPQGS 152
|
| Sus scrofa |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||||||||||||||||| |||||||| #|||||||||||||||+| ||||||||||||
Sbjct 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174
|
| Mus musculus |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
| ||||| +||||||+|||||| |||||| #||||||| |||+|| |||| |||||||
Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKIRDRS----KMKIVGTPREEPRPVPQGS 169
|
| Rattus norvegicus |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
| ||||| +||||||+|||||| |||||| #||+|||| |||||| |||| |||||||
Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKVRDRS----KMKVVGTPREEPRPVPQGS 169
|
| Monodelphis domestica |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVG--VPREEARPVPQ 71
| ++|+| +||||||||||+|||+|+||| #|||| |++ |||| +| ||+ ||+ |
Sbjct 114 QTTEKEESEHPNNSFSPCSSHDRKCMQKHS#AKIRVVSSNSGKMKSIGSSAHREDTRPMAQ 173
Query 72 GS 73
||
Query 72 GS 73
|
| Gallus gallus |
Query 14 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVP--REEARPVPQ 71
|| +|+| +|||||||||| |||+|||| #|| | +| ||+ | | |||+||+ |
Sbjct 119 QPPEKEEIEHPNNSFSPCSIHDRKCLQKQQ#AK---RINNGNKMRSSGSPHHREESRPIAQ 175
Query 72 GS 73
||
Query 72 GS 73
|
| Bubalus bubalis |
Query 38 CLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 73
||||| #|||||||||||||||+| ||||||||||||
Sbjct 1 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 36
|
| Tetraodon nigroviridis |
Query 22 DHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTS 52
+||||| || |+||+|| #|+ +||+
Sbjct 130 EHPNNSNIRCSQQDKRCIQKTL#ARHLSKSTN 160
|
[Site 2] STSGGKMKVV59-GVPREEARPV
Val59 Gly
|
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Ser50 | Thr51 | Ser52 | Gly53 | Gly54 | Lys55 | Met56 | Lys57 | Val58 | Val59 |
|
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Gly60 | Val61 | Pro62 | Arg63 | Glu64 | Glu65 | Ala66 | Arg67 | Pro68 | Val69 |
Sequence conservation (by blast) Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
PCSAHDRRCLQKHFAKIRDRSTSGGKMKVVGVPREEARPVPQGSCQSELHRALERLAASQ
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Canis familiaris |
125.00 |
1 |
PREDICTED: similar to Insulin-like growth factor b |
| 2 |
Equus caballus |
125.00 |
1 |
insulin-like growth factor binding protein-4 |
| 3 |
N/A |
120.00 |
3 |
- |
| 4 |
Homo sapiens |
120.00 |
2 |
insulin-like growth factor binding protein 4 precu |
| 5 |
Bos taurus |
120.00 |
2 |
insulin-like growth factor-binding protein 4 |
| 6 |
synthetic construct |
120.00 |
2 |
insulin-like growth factor binding protein 4 |
| 7 |
Pan troglodytes |
120.00 |
1 |
PREDICTED: similar to Insulin-like growth factor-b |
| 8 |
Ovis aries |
119.00 |
1 |
IBP4_SHEEP Insulin-like growth factor-binding prot |
| 9 |
Sus scrofa |
116.00 |
1 |
IBP4 |
| 10 |
Mus musculus |
103.00 |
3 |
insulin-like growth factor binding protein-4 |
| 11 |
Rattus norvegicus |
103.00 |
1 |
insulin-like growth factor binding protein 4 |
| 12 |
Bubalus bubalis |
103.00 |
1 |
insulin-like growth factor binding protein-4 |
| 13 |
Monodelphis domestica |
87.00 |
1 |
PREDICTED: similar to SWI/SNF-related matrix-assoc |
| 14 |
Gallus gallus |
79.70 |
1 |
insulin-like growth factor binding protein 4 |
| 15 |
Tetraodon nigroviridis |
38.90 |
1 |
unnamed protein product |
| 16 |
Oncorhynchus mykiss |
36.60 |
1 |
insulin-like growth factor binding protein 4 |
Top-ranked sequences
| organism | matching |
|---|
| Canis familiaris |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|||||||||||||||||||||||||||||+#||||||||||||||||||||||||||||||
Sbjct 323 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVI#GVPREEARPVPQGSCQSELHRALERLAASQ 382
|
| Equus caballus |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||||||||||||||||||||||||||||#||||||||||||||||||||||||||||||
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|
| N/A |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||||||||||||||||||||||||||| #| |||+||||||||||||||||||||||||
Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189
|
| Homo sapiens |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||||||||||||||||||||||||||| #| |||+||||||||||||||||||||||||
Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189
|
| Bos taurus |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|||||||+||||| |||||||||||||||+#| ||||||||||||||||||||||||||||
Sbjct 13 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 72
|
| synthetic construct |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||||||||||||||||||||||||||| #| |||+||||||||||||||||||||||||
Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189
|
| Pan troglodytes |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||||||||||||||||||||||||||| #| |||+||||||||||||||||||||||||
Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189
|
| Ovis aries |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|||||||+||||| |||||||||||||||+#| |||| |||||||||||||||||||||||
Sbjct 109 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEVRPVPQGSCQSELHRALERLAASQ 168
|
| Sus scrofa |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||| |||||||| |||||||||||||||+#| ||||||||||||||||||||||||||||
Sbjct 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190
|
| Mus musculus |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|||||| |||||| ||||||| |||+|#| |||| |||||||||||||||||||||||
Sbjct 130 PCSAHDHRCLQKHMAKIRDRS----KMKIV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185
|
| Rattus norvegicus |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
|||||| |||||| ||+|||| |||||#| |||| |||||||||||||||||||||||
Sbjct 130 PCSAHDHRCLQKHMAKVRDRS----KMKVV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185
|
| Bubalus bubalis |
Query 38 CLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 89
||||| |||||||||||||||+#| ||||||||||||||||||||||||||||
Sbjct 1 CLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 52
|
| Monodelphis domestica |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#G--VPREEARPVPQGSCQSELHRALERLAA 87
|||+|||+|+||| |||| |++ |||| +#| ||+ ||+ ||||||||||||||| |
Sbjct 130 PCSSHDRKCMQKHSAKIRVVSSNSGKMKSI#GSSAHREDTRPMAQGSCQSELHRALERLGA 189
Query 88 SQ 89
||
Query 88 SQ 89
|
| Gallus gallus |
Query 30 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVP--REEARPVPQGSCQSELHRALERLAA 87
||| |||+|||| || | +| ||+ #| | |||+||+ |||||||||||||||||
Sbjct 135 PCSIHDRKCLQKQQAK---RINNGNKMRSS#GSPHHREESRPIAQGSCQSELHRALERLAA 191
Query 88 SQ 89
||
Query 88 SQ 89
|
| Tetraodon nigroviridis |
Query 31 CSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAAS 88
|| |+||+|| |+ +||+ + # ||| + | |++|| |||+|||++
Sbjct 139 CSQQDKRCIQKTLARHLSKSTN----QRS#NSGREETKAV-LAPCRAELQRALDRLASN 191
|
| Oncorhynchus mykiss |
Query 31 CSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAAS 88
|| |+||+|| |+ +||+ # |+ | |++|| |||+|| ++
Sbjct 19 CSPQDKRCIQKTLARHPAKSTNQRSNNAR#EDPKAALAP-----CRAELQRALDRLVSN 71
|
