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XSB2834 : insulin-like growth factor binding protein 4 [Sus scrofa]

[ CaMP Format ]

This entry is computationally expanded from SB0070

* Basic Information

OrganismSus scrofa (pig)
Protein NamesInsulin-like growth factor-binding protein 4; IGF-binding protein 4; IGFBP-4; IBP-4; insulin-like growth factor binding protein 4
Gene NamesIBP4; IGFBP4; insulin-like growth factor binding protein 4
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001116601 NM_001123129 100144490 IBP4_PIG N/A N/A N/A ssc:100144490

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 259 aa

Average Mass: 28.230 kDa

Monoisotopic Mass: 28.212 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
IGFBP 1. 2886101.62.6e-27
--- cleavage 144 ---
--- cleavage 160 ---
--- cleavage 108 ---
Thyroglobulin_1 1. 175250142.21.6e-39

3. Sequence Information

Fasta Sequence: XSB2834.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

3 [sites]

Cleavage sites (±10aa)

[Site 1] QDRRCLQKHL144-AKIRDRSTSG

Leu144 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gln135Asp136Arg137Arg138Cys139Leu140Gln141Lys142His143Leu144
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala145Lys146Ile147Arg148Asp149Arg150Ser151Thr152Ser153Gly154

Sequence conservation (by blast)

[Site 2] STSGGKMKVI160-GAPREEARPV

Ile160 Gly

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Ser151Thr152Ser153Gly154Gly155Lys156Met157Lys158Val159Ile160
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Gly161Ala162Pro163Arg164Glu165Glu166Ala167Arg168Pro169Val170

Sequence conservation (by blast)

[Site 3] GLCMELAEIE108-AIQESLQPSD

Glu108 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Gly99Leu100Cys101Met102Glu103Leu104Ala105Glu106Ile107Glu108
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala109Ile110Gln111Glu112Ser113Leu114Gln115Pro116Ser117Asp118

Sequence conservation (by blast)

* References

[PubMed ID: 1722398] Coleman ME, Pan YC, Etherton TD, Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1131-6.