XSB2834 : insulin-like growth factor binding protein 4 [Sus scrofa]
[ CaMP Format ]
This entry is computationally expanded from SB0070
* Basic Information
Organism | Sus scrofa (pig) |
Protein Names | Insulin-like growth factor-binding protein 4; IGF-binding protein 4; IGFBP-4; IBP-4; insulin-like growth factor binding protein 4 |
Gene Names | IBP4; IGFBP4; insulin-like growth factor binding protein 4 |
Gene Locus | Not available |
GO Function | Not available |
Entrez Protein | Entrez Nucleotide | Entrez Gene | UniProt | OMIM | HGNC | HPRD | KEGG |
---|---|---|---|---|---|---|---|
NP_001116601 | NM_001123129 | 100144490 | IBP4_PIG | N/A | N/A | N/A | ssc:100144490 |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 259 aa
Average Mass: 28.230 kDa
Monoisotopic Mass: 28.212 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
domain name | begin | end | score | e-value |
---|---|---|---|---|
IGFBP 1. | 28 | 86 | 101.6 | 2.6e-27 |
--- cleavage 144 --- | ||||
--- cleavage 160 --- | ||||
--- cleavage 108 --- | ||||
Thyroglobulin_1 1. | 175 | 250 | 142.2 | 1.6e-39 |
3. Sequence Information
Fasta Sequence: XSB2834.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
3 [sites]
Cleavage sites (±10aa)
[Site 1] QDRRCLQKHL144-AKIRDRSTSG
Leu144 Ala
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P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Gln135 | Asp136 | Arg137 | Arg138 | Cys139 | Leu140 | Gln141 | Lys142 | His143 | Leu144 |
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P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Ala145 | Lys146 | Ile147 | Arg148 | Asp149 | Arg150 | Ser151 | Thr152 | Ser153 | Gly154 |
Sequence conservation (by blast)
Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
QPSDKDEGDHPNNSFSPCSPQDRRCLQKHLAKIRDRSTSGGKMKVIGAPREEARPVPQGS |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | Sus scrofa | 129.00 | 1 | IBP4 |
2 | Bos taurus | 123.00 | 2 | insulin-like growth factor binding protein 4 |
3 | Ovis aries | 122.00 | 1 | IBP4_SHEEP Insulin-like growth factor-binding prot |
4 | Equus caballus | 121.00 | 1 | insulin-like growth factor binding protein-4 |
5 | Canis familiaris | 121.00 | 1 | PREDICTED: similar to Insulin-like growth factor b |
6 | Homo sapiens | 119.00 | 2 | insulin-like growth factor binding protein 4 precu |
7 | N/A | 119.00 | 2 | - |
8 | synthetic construct | 119.00 | 2 | insulin-like growth factor binding protein 4 |
9 | Pan troglodytes | 119.00 | 1 | PREDICTED: similar to Insulin-like growth factor-b |
10 | Mus musculus | 95.90 | 3 | insulin-like growth factor binding protein-4 |
11 | Rattus norvegicus | 95.90 | 2 | insulin-like growth factor binding protein 4 |
12 | Monodelphis domestica | 80.10 | 1 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
13 | Bubalus bubalis | 76.30 | 1 | insulin-like growth factor binding protein-4 |
14 | Gallus gallus | 71.60 | 1 | insulin-like growth factor binding protein 4 |
15 | Oncorhynchus mykiss | 42.70 | 1 | insulin-like growth factor binding protein 4 |
16 | Tetraodon nigroviridis | 40.00 | 1 | unnamed protein product |
Top-ranked sequences
organism | matching |
---|---|
Sus scrofa | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 |
Bos taurus | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| ||+||||||#|||||||||||||||||||||||||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 173 |
Ovis aries | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| ||+||||||#|||||||||||||||||||||| ||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRKCLQKHL#AKIRDRSTSGGKMKVIGAPREEVRPVPQGS 152 |
Equus caballus | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #|||||||||||||||+| |||||||||||| Sbjct 93 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVVGVPREEARPVPQGS 152 |
Canis familiaris | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #||||||||||||||||| |||||||||||| Sbjct 307 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVIGVPREEARPVPQGS 366 |
Homo sapiens | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
N/A | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
synthetic construct | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
Pan troglodytes | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||||||||||||||| |||||||| #||||||||||||||| |||||+|||||||| Sbjct 114 QPSDKDEGDHPNNSFSPCSAHDRRCLQKHF#AKIRDRSTSGGKMKVNGAPREDARPVPQGS 173 |
Mus musculus | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 | ||||| +||||||+||| | ||||||+#||||||| |||++| |||| ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKIRDRS----KMKIVGTPREEPRPVPQGS 169 |
Rattus norvegicus | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 | ||||| +||||||+||| | ||||||+#||+|||| ||||+| |||| ||||||| Sbjct 114 QTSDKDESEHPNNSFNPCSAHDHRCLQKHM#AKVRDRS----KMKVVGTPREEPRPVPQGS 169 |
Monodelphis domestica | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIG--APREEARPVPQ 172 | ++|+| +|||||||||| ||+|+||| #|||| |++ |||| || | ||+ ||+ | Sbjct 114 QTTEKEESEHPNNSFSPCSSHDRKCMQKHS#AKIRVVSSNSGKMKSIGSSAHREDTRPMAQ 173 Query 173 GS 174 || Query 173 GS 174 |
Bubalus bubalis | Query 139 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 ||||||#|||||||||||||||||||||||||||||| Query 139 CLQKHL#AKIRDRSTSGGKMKVIGAPREEARPVPQGS 174 |
Gallus gallus | Query 115 QPSDKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTSGGKMKVIGAP--REEARPVPQ 172 || +|+| +|||||||||| ||+|||| #|| | +| ||+ |+| |||+||+ | Sbjct 119 QPPEKEEIEHPNNSFSPCSIHDRKCLQKQQ#AK---RINNGNKMRSSGSPHHREESRPIAQ 175 Query 173 GS 174 || Query 173 GS 174 |
Oncorhynchus mykiss | Query 118 DKDEGDHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTS 153 |+ +||||| |||||+||+|| |#|+ +||+ Sbjct 5 DETIPEHPNNSNIRCSPQDKRCIQKTL#ARHPAKSTN 40 |
Tetraodon nigroviridis | Query 123 DHPNNSFSPCSPQDRRCLQKHL#AKIRDRSTS 153 +||||| || ||+||+|| |#|+ +||+ Sbjct 130 EHPNNSNIRCSQQDKRCIQKTL#ARHLSKSTN 160 |
[Site 2] STSGGKMKVI160-GAPREEARPV
Ile160 Gly
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P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Ser151 | Thr152 | Ser153 | Gly154 | Gly155 | Lys156 | Met157 | Lys158 | Val159 | Ile160 |
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P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Gly161 | Ala162 | Pro163 | Arg164 | Glu165 | Glu166 | Ala167 | Arg168 | Pro169 | Val170 |
Sequence conservation (by blast)
Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
PCSPQDRRCLQKHLAKIRDRSTSGGKMKVIGAPREEARPVPQGSCQSELHRALERLAASQ |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | Sus scrofa | 125.00 | 1 | IBP4 |
2 | Bos taurus | 119.00 | 2 | insulin-like growth factor binding protein 4 |
3 | Ovis aries | 117.00 | 1 | IBP4_SHEEP Insulin-like growth factor-binding prot |
4 | Canis familiaris | 117.00 | 1 | PREDICTED: similar to Insulin-like growth factor b |
5 | Equus caballus | 116.00 | 1 | insulin-like growth factor binding protein-4 |
6 | Homo sapiens | 114.00 | 2 | insulin-like growth factor binding protein 4 precu |
7 | N/A | 114.00 | 2 | - |
8 | synthetic construct | 114.00 | 2 | insulin-like growth factor binding protein 4 |
9 | Pan troglodytes | 114.00 | 1 | PREDICTED: similar to Insulin-like growth factor-b |
10 | Bubalus bubalis | 106.00 | 1 | insulin-like growth factor binding protein-4 |
11 | Mus musculus | 99.40 | 3 | insulin-like growth factor binding protein-4 |
12 | Rattus norvegicus | 99.40 | 1 | insulin-like growth factor binding protein 4 |
13 | Monodelphis domestica | 85.10 | 1 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
14 | Gallus gallus | 77.40 | 1 | insulin-like growth factor binding protein 4 |
15 | Tetraodon nigroviridis | 43.50 | 1 | unnamed protein product |
16 | Oncorhynchus mykiss | 43.50 | 1 | insulin-like growth factor binding protein 4 |
Top-ranked sequences
organism | matching |
---|---|
Sus scrofa | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 |
Bos taurus | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| ||+||||||||||||||||||||||#|||||||||||||||||||||||||||||| Sbjct 130 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 189 |
Ovis aries | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| ||+||||||||||||||||||||||#|||||| ||||||||||||||||||||||| Sbjct 109 PCSAHDRKCLQKHLAKIRDRSTSGGKMKVI#GAPREEVRPVPQGSCQSELHRALERLAASQ 168 |
Canis familiaris | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| ||||||||||||||||#| |||||||||||||||||||||||||||| Sbjct 323 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVI#GVPREEARPVPQGSCQSELHRALERLAASQ 382 |
Equus caballus | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| |||||||||||||||+#| |||||||||||||||||||||||||||| Sbjct 109 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVV#GVPREEARPVPQGSCQSELHRALERLAASQ 168 |
Homo sapiens | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189 |
N/A | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189 |
synthetic construct | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189 |
Pan troglodytes | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| |||||||| ||||||||||||||| #|||||+|||||||||||||||||||||||| Sbjct 130 PCSAHDRRCLQKHFAKIRDRSTSGGKMKVN#GAPREDARPVPQGSCQSELHRALERLAASQ 189 |
Bubalus bubalis | Query 139 CLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 139 CLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 |
Mus musculus | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| | ||||||+||||||| |||++#| |||| ||||||||||||||||||||||| Sbjct 130 PCSAHDHRCLQKHMAKIRDRS----KMKIV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185 |
Rattus norvegicus | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAASQ 190 ||| | ||||||+||+|||| ||||+#| |||| ||||||||||||||||||||||| Sbjct 130 PCSAHDHRCLQKHMAKVRDRS----KMKVV#GTPREEPRPVPQGSCQSELHRALERLAASQ 185 |
Monodelphis domestica | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#G--APREEARPVPQGSCQSELHRALERLAA 188 ||| ||+|+||| |||| |++ |||| |#| | ||+ ||+ ||||||||||||||| | Sbjct 130 PCSSHDRKCMQKHSAKIRVVSSNSGKMKSI#GSSAHREDTRPMAQGSCQSELHRALERLGA 189 Query 189 SQ 190 || Query 189 SQ 190 |
Gallus gallus | Query 131 PCSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAP--REEARPVPQGSCQSELHRALERLAA 188 ||| ||+|||| || | +| ||+ #|+| |||+||+ ||||||||||||||||| Sbjct 135 PCSIHDRKCLQKQQAK---RINNGNKMRSS#GSPHHREESRPIAQGSCQSELHRALERLAA 191 Query 189 SQ 190 || Query 189 SQ 190 |
Tetraodon nigroviridis | Query 132 CSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAAS 189 || ||+||+|| ||+ +||+ + # + ||| + | |++|| |||+|||++ Sbjct 139 CSQQDKRCIQKTLARHLSKSTN----QRS#NSGREETKAV-LAPCRAELQRALDRLASN 191 |
Oncorhynchus mykiss | Query 132 CSPQDRRCLQKHLAKIRDRSTSGGKMKVI#GAPREEARPVPQGSCQSELHRALERLAAS 189 |||||+||+|| ||+ +||+ # |+ | |++|| |||+|| ++ Sbjct 19 CSPQDKRCIQKTLARHPAKSTNQRSNNAR#EDPKAALAP-----CRAELQRALDRLVSN 71 |
[Site 3] GLCMELAEIE108-AIQESLQPSD
Glu108 Ala
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P10 | P9 | P8 | P7 | P6 | P5 | P4 | P3 | P2 | P1 |
---|---|---|---|---|---|---|---|---|---|
Gly99 | Leu100 | Cys101 | Met102 | Glu103 | Leu104 | Ala105 | Glu106 | Ile107 | Glu108 |
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P1' | P2' | P3' | P4' | P5' | P6' | P7' | P8' | P9' | P10' |
Ala109 | Ile110 | Gln111 | Glu112 | Ser113 | Leu114 | Gln115 | Pro116 | Ser117 | Asp118 |
Sequence conservation (by blast)
Sequence conservation (by blast)
Reference peptide (cleaved bond±30 residues) |
---|
LRCYPPRGVEKPLHTLMHGQGLCMELAEIEAIQESLQPSDKDEGDHPNNSFSPCSPQDRR |
Summary
# | organism | max score | hits | top seq |
---|---|---|---|---|
1 | Sus scrofa | 132.00 | 5 | IBP4 |
2 | Pan troglodytes | 127.00 | 3 | PREDICTED: similar to Insulin-like growth factor-b |
3 | Homo sapiens | 126.00 | 15 | insulin-like growth factor binding protein 4 precu |
4 | N/A | 126.00 | 11 | - |
5 | synthetic construct | 126.00 | 10 | insulin-like growth factor binding protein 4 |
6 | Canis familiaris | 125.00 | 4 | PREDICTED: similar to Insulin-like growth factor b |
7 | Equus caballus | 125.00 | 2 | insulin-like growth factor binding protein-4 |
8 | Bos taurus | 123.00 | 5 | insulin-like growth factor binding protein 4 |
9 | Ovis aries | 121.00 | 3 | IBP4_SHEEP Insulin-like growth factor-binding prot |
10 | Monodelphis domestica | 111.00 | 3 | PREDICTED: similar to SWI/SNF-related matrix-assoc |
11 | Mus musculus | 108.00 | 9 | unnamed protein product |
12 | Rattus norvegicus | 108.00 | 6 | insulin-like growth factor binding protein 4 |
13 | Gallus gallus | 105.00 | 3 | insulin-like growth factor binding protein 4 |
14 | Tetraodon nigroviridis | 72.00 | 7 | unnamed protein product |
15 | Xenopus tropicalis | 44.30 | 3 | Unknown (protein for MGC:144994) |
16 | Xenopus laevis | 43.10 | 3 | insulin-like growth factor binding protein 5 |
17 | Danio rerio | 40.80 | 7 | PREDICTED: similar to Igfbp5 protein |
18 | Salmo salar | 40.00 | 1 | IGF binding protein 5 |
19 | Oncorhynchus mykiss | 40.00 | 1 | insulin-like growth factor binding protein 5 |
20 | Macaca mulatta | 39.30 | 5 | PREDICTED: similar to insulin-like growth factor b |
21 | Bubalus bubalis | 38.50 | 1 | insulin-like growth factor binding protein-5 |
22 | Coturnix japonica | 38.10 | 1 | AF293839_1 insulin-like growth factor binding prot |
Top-ranked sequences
organism | matching |
---|---|
Sus scrofa | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||||||||||||||||||||||||#|||||||||||||||||||||||||||||| Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |
Pan troglodytes | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||||||||||||||||||||||||#||||||||||||||||||||||||| ||| Sbjct 78 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
Homo sapiens | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||||||||||||||||||||+||||||||#||||||||||||||||||||||||| ||| Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
N/A | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||||||||||||||||||||+||||||||#||||||||||||||||||||||||| ||| Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
synthetic construct | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||||||||||||||||||||+||||||||#||||||||||||||||||||||||| ||| Sbjct 78 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 137 |
Canis familiaris | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||||||||||||||||||||+||||+|||#||||||||||||||||||||||||| ||| Sbjct 271 LRCYPPRGVEKPLHTLMHGQGVCMELSEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRR 330 |
Equus caballus | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||||||||||||||||||||+||||||||#||||+|||||||||||||||||||| ||| Sbjct 57 LRCYPPRGVEKPLHTLMHGQGVCMELAEIE#AIQENLQPSDKDEGDHPNNSFSPCSAHDRR 116 |
Bos taurus | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||||||||||+||||+||||||||#||||||||||||||||||||||||| ||+ Sbjct 78 LRCYPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 137 |
Ovis aries | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 |||+||||||||||||+||||+||||||||#||||||||||||||||||||||||| ||+ Sbjct 57 LRCHPPRGVEKPLHTLVHGQGVCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSAHDRK 116 |
Monodelphis domestica | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||||||||||||||| |||||+||#||||||| ++|+| +|||||||||| ||+ Sbjct 78 LRCYPPRGVEKPLHTLMHGQGECMELADIE#AIQESLQTTEKEESEHPNNSFSPCSSHDRK 137 |
Mus musculus | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 +|||||||||||| |||||||+| ||+|||#||||||| ||||| +||||||+||| | | Sbjct 78 MRCYPPRGVEKPLRTLMHGQGVCTELSEIE#AIQESLQTSDKDESEHPNNSFNPCSAHDHR 137 |
Rattus norvegicus | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 +|||||||||||| |||||||+| ||+|||#||||||| ||||| +||||||+||| | | Sbjct 78 MRCYPPRGVEKPLRTLMHGQGVCTELSEIE#AIQESLQTSDKDESEHPNNSFNPCSAHDHR 137 |
Gallus gallus | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||| +||||||||||+| +||++|#|||||||| +|+| +|||||||||| ||+ Sbjct 83 LRCYPPRGVPRPLHTLMHGQGVCTDLADVE#AIQESLQPPEKEEIEHPNNSFSPCSIHDRK 142 |
Tetraodon nigroviridis | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDRR 138 ||||||||||+|||+||||||+| + |+|# + |+ +||||| || ||+| Sbjct 87 LRCYPPRGVERPLHSLMHGQGVCTDEREVE#E-NSATDRQDEIIPEHPNNSNIRCSQQDKR 145 |
Xenopus tropicalis | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMEL------AEIE#AIQE 112 ||| | +| ||||| |+||+|+|+ | ++|+#+|+| Sbjct 78 LRCLPEQGEEKPLHALLHGRGVCLNLKNHRDQSKID#SIEE 117 |
Xenopus laevis | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMEL 104 ||| | +| ||||| |+||+|+|+ | Sbjct 79 LRCLPEQGEEKPLHALLHGRGVCLNL 104 |
Danio rerio | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNSFSPCSPQDR 137 ||| | | ||||| |+||+|+| +# + | |++ +| +++ | + +|+ Sbjct 74 LRCLPRNGEEKPLHALLHGRGVC---TNEK#GYKPPHPPIDRESIEH-DDTVKPDTTEDQ 128 |
Salmo salar | Query 79 LRCYPPRGVEKPLHTLMHGQGLC 101 ||| | | ||||| |+||+|+| Sbjct 76 LRCLPRNGEEKPLHALLHGRGVC 98 |
Oncorhynchus mykiss | Query 79 LRCYPPRGVEKPLHTLMHGQGLC 101 ||| | | ||||| |+||+|+| Sbjct 76 LRCLPRNGEEKPLHALLHGRGVC 98 |
Macaca mulatta | Query 79 LRCYPPRGVEKPLHTLMHGQGLCME----LAEIE#AIQESLQPSDKDEGDHPNNSFSP 131 ||| | + ||||| |+||+|+|+ +++# ++| + + + ++|| Sbjct 78 LRCLPRQDEEKPLHALLHGRGVCLNEKSYREQVK#IERDSREHEEPTTSEMAEETYSP 134 |
Bubalus bubalis | Query 79 LRCYPPRGVEKPLHTLMHGQGLCM 102 ||| | + ||||| |+||+|+|+ Sbjct 34 LRCLPRQDEEKPLHALLHGRGVCL 57 |
Coturnix japonica | Query 79 LRCYPPRGVEKPLHTLMHGQGLCMELAEIE#AIQESLQPSDKDEGDHPNNS 128 +|| | +| ||||| |+|| +| |+| # +++ + | + | | Sbjct 34 VRCLPRQGEEKPLHALLHGTAVC--LSEKS#YREQAKAERESREHEEPTTS 81 |
* References
[PubMed ID: 1722398] Coleman ME, Pan YC, Etherton TD, Identification and NH2-terminal amino acid sequence of three insulin-like growth factor-binding proteins in porcine serum. Biochem Biophys Res Commun. 1991 Dec 31;181(3):1131-6.