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XSB2858 : phosphorylase kinase, gamma 1 (muscle) [Oryctolagus cuniculus]

[ CaMP Format ]

This entry is computationally expanded from SB0018

* Basic Information

OrganismOryctolagus cuniculus (rabbit)
Protein NamesPhosphorylase b kinase gamma catalytic chain, skeletal muscle isoform; 2.7.11.19; Phosphorylase kinase subunit gamma 1; phosphorylase kinase; gamma 1 (muscle); phosphorylase kinase gamma 1
Gene NamesPHKG1; PHKG; phosphorylase kinase, gamma 1 (muscle)
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_001095175 NM_001101705 100009297 PHKG1_RABIT N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 387 aa

Average Mass: 44.803 kDa

Monoisotopic Mass: 44.774 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Pkinase 1. 20288345.97.7e-101

3. Sequence Information

Fasta Sequence: XSB2858.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Known Structures in PDB: 1PHK (X-ray; 220 A; A=2-299), 1QL6 (X-ray; 240 A; A=2-299), 2PHK (X-ray; 260 A; A=15-291)

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] EEVRHFSPRG303-KFKVICLTVL

Gly303 Lys

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu294Glu295Val296Arg297His298Phe299Ser300Pro301Arg302Gly303
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Lys304Phe305Lys306Val307Ile308Cys309Leu310Thr311Val312Leu313

Sequence conservation (by blast)

* References

[PubMed ID: 9362479] Lowe ED, Noble ME, Skamnaki VT, Oikonomakos NG, Owen DJ, Johnson LN, The crystal structure of a phosphorylase kinase peptide substrate complex: kinase substrate recognition. EMBO J. 1997 Nov 17;16(22):6646-58.

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