logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2875 : spectrin beta 1, isoform CRA_a [Mus musculus]

[ CaMP Format ]

This entry is computationally expanded from SB0052

* Basic Information

OrganismMus musculus (house mouse)
Protein Namesspectrin beta 1; isoform CRA_a
Gene NamesSpnb1
Gene LocusNot available
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
EDL36451 N/A 20741 N/A N/A N/A N/A N/A

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 2137 aa

Average Mass: 246.333 kDa

Monoisotopic Mass: 246.180 kDa

2. Domain Information

Annotated Domains: Not Available.

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
CH 1. 55158118.22.7e-32
CH 2. 174278148.91.5e-41
Spectrin 1. 30241269.41.3e-17
Spectrin 2. 422526107.35.2e-29
Spectrin 3. 52863591.92.2e-24
Spectrin 4. 637741126.68.1e-35
Spectrin 5. 743846101.23.4e-27
Spectrin 6. 84895258.72.1e-14
Spectrin 7. 954105974.63.7e-19
Spectrin 8. 1061116694.82.9e-25
Spectrin 9. 1168127217.10.0012
Spectrin 10. 12741377108.71.9e-29
Spectrin 11. 1381147625.30.00024
Spectrin 12. 1478158275.81.6e-19
Spectrin 13. 1584168889.89.4e-24
Spectrin 14. 16901795115.71.5e-31
Spectrin 15. 1797190185.32.2e-22
Spectrin 16. 19032007100.55.8e-27
Spectrin 17. 2009211726.40.00012
--- cleavage 2061 (inside Spectrin 2009..2117) ---

3. Sequence Information

Fasta Sequence: XSB2875.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] EAFEKSTASW2061-AERFAALEKP

Trp2061 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Glu2052Ala2053Phe2054Glu2055Lys2056Ser2057Thr2058Ala2059Ser2060Trp2061
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala2062Glu2063Arg2064Phe2065Ala2066Ala2067Leu2068Glu2069Lys2070Pro2071

Sequence conservation (by blast)

* References

[PubMed ID: 12040188] Mural RJ, Adams MD, Myers EW, Smith HO, Miklos GL, Wides R, Halpern A, Li PW, Sutton GG, Nadeau J, Salzberg SL, Holt RA, Kodira CD, Lu F, Chen L, Deng Z, Evangelista CC, Gan W, Heiman TJ, Li J, Li Z, Merkulov GV, Milshina NV, Naik AK, Qi R, Shue BC, Wang A, Wang J, Wang X, Yan X, Ye J, Yooseph S, Zhao Q, Zheng L, Zhu SC, Biddick K, Bolanos R, Delcher AL, Dew IM, Fasulo D, Flanigan MJ, Huson DH, Kravitz SA, Miller JR, Mobarry CM, Reinert K, Remington KA, Zhang Q, Zheng XH, Nusskern DR, Lai Z, Lei Y, Zhong W, Yao A, Guan P, Ji RR, Gu Z, Wang ZY, Zhong F, Xiao C, Chiang CC, Yandell M, Wortman JR, Amanatides PG, Hladun SL, Pratts EC, Johnson JE, Dodson KL, Woodford KJ, Evans CA, Gropman B, Rusch DB, Venter E, Wang M, Smith TJ, Houck JT, Tompkins DE, Haynes C, Jacob D, Chin SH, Allen DR, Dahlke CE, Sanders R, Li K, Liu X, Levitsky AA, Majoros WH, Chen Q, Xia AC, Lopez JR, Donnelly MT, Newman MH, Glodek A, Kraft CL, Nodell M, Ali F, An HJ, Baldwin-Pitts D, Beeson KY, Cai S, Carnes M, Carver A, Caulk PM, Center A, Chen YH, Cheng ML, Coyne MD, Crowder M, Danaher S, Davenport LB, Desilets R, Dietz SM, Doup L, Dullaghan P, Ferriera S, Fosler CR, Gire HC, Gluecksmann A, Gocayne JD, Gray J, Hart B, Haynes J, Hoover J, Howland T, Ibegwam C, Jalali M, Johns D, Kline L, Ma DS, MacCawley S, Magoon A, Mann F, May D, McIntosh TC, Mehta S, Moy L, Moy MC, Murphy BJ, Murphy SD, Nelson KA, Nuri Z, Parker KA, Prudhomme AC, Puri VN, Qureshi H, Raley JC, Reardon MS, Regier MA, Rogers YH, Romblad DL, Schutz J, Scott JL, Scott R, Sitter CD, Smallwood M, Sprague AC, Stewart E, Strong RV, Suh E, Sylvester K, Thomas R, Tint NN, Tsonis C, Wang G, Wang G, Williams MS, Williams SM, Windsor SM, Wolfe K, Wu MM, Zaveri J, Chaturvedi K, Gabrielian AE, Ke Z, Sun J, Subramanian G, Venter JC, Pfannkoch CM, Barnstead M, Stephenson LD, A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome. Science. 2002 May 31;296(5573):1661-71.