XSB2912 : protein tyrosine phosphatase-like protein [Rattus sp.]
[ CaMP Format ]
This entry is computationally expanded from SB0024
* Basic Information
| Organism | Rattus sp. |
| Protein Names | Receptor-type tyrosine-protein phosphatase-like N; R-PTP-N; 105 kDa islet cell antigen; ICA105; PTP IA-2; PTPLP; Brain-enriched membrane-associated protein tyrosine phosphatase; BEM-3; protein tyrosine phosphatase-like protein |
| Gene Names | Ptprn |
| Gene Locus | Not available |
| GO Function | Not available |
* Information From OMIM
Not Available.
* Structure Information
1. Primary Information
Length: 922 aa
Average Mass: 100.143 kDa
Monoisotopic Mass: 100.081 kDa
2. Domain Information
Annotated Domains: interpro / pfam / smart / prosite
Computationally Assigned Domains (Pfam+HMMER):
| domain name | begin | end | score | e-value |
| Drf_FH1 1. | 16 | 175 | -37.7 | 3.1 |
| DUF1008 1. | 223 | 306 | -101.5 | 8.6 |
| FDX-ACB 1. | 417 | 493 | -52.3 | 2 |
| FCD 1. | 526 | 648 | -29.0 | 7.4 |
| --- cleavage 601 (inside FCD 526..648) --- |
| Y_phosphatase 1. | 677 | 911 | 386.2 | 5.8e-113 |
3. Sequence Information
Fasta Sequence: XSB2912.fasta
Amino Acid Sequence and Secondary Structures (PsiPred):
4. 3D Information
Not Available.
* Cleavage Information
1 [sites]
Cleavage sites (±10aa)
[Site 1] PEPSRVSSVS601-SQFSDAAQAS
Ser601 
Ser
 |
| P10 | P9 | P8 | P7 | P6 |
P5 | P4 | P3 | P2 | P1 |
| Pro592 | Glu593 | Pro594 | Ser595 | Arg596 | Val597 | Ser598 | Ser599 | Val600 | Ser601 |
 |
| P1' | P2' | P3' | P4' | P5' |
P6' | P7' | P8' | P9' | P10' |
| Ser602 | Gln603 | Phe604 | Ser605 | Asp606 | Ala607 | Ala608 | Gln609 | Ala610 | Ser611 |
Sequence conservation (by blast)
Sequence conservation (by blast)
| Reference peptide (cleaved bond±30 residues) |
|---|
|
QDLCRQHMATKSLFNRAEGQPEPSRVSSVSSQFSDAAQASPSSHSSTPSWCEEPAQANMD
|
Summary
| # |
organism |
max score |
hits |
top seq |
| 1 |
Mus musculus |
57.80 |
9 |
AF332083_1 protein tyrosine phosphatase receptor t |
| 2 |
Homo sapiens |
57.80 |
5 |
PTPRN protein |
| 3 |
N/A |
57.80 |
4 |
- |
| 4 |
Rattus norvegicus |
57.80 |
2 |
protein tyrosine phosphatase, receptor type, N |
| 5 |
Pan troglodytes |
57.80 |
1 |
PREDICTED: protein tyrosine phosphatase, receptor |
| 6 |
Bos taurus |
57.80 |
1 |
protein tyrosine phosphatase, receptor type, N |
| 7 |
Pongo pygmaeus |
57.80 |
1 |
hypothetical protein |
| 8 |
synthetic construct |
57.80 |
1 |
Homo sapiens protein tyrosine phosphatase, recepto |
| 9 |
Rattus sp. |
57.80 |
1 |
BAA07397.1 |
| 10 |
Canis familiaris |
53.90 |
2 |
PREDICTED: similar to Receptor-type tyrosine-prote |
Top-ranked sequences
| organism | matching |
|---|
| Mus musculus |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 526 QDLCRQHMATKSLFNRAEGQPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 585
|
| Homo sapiens |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 600 QDLCRQHMATKSLFNRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 659
|
| N/A |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 621 QDLCRQHMATKSLFNRAEGQPEPSRVSSVS#SKFSDAAQANPSSHSSTPSWCEEPAQANMD 680
|
| Rattus norvegicus |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 633 QDLCRQHMATKSLFNRAEGQPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 692
|
| Pan troglodytes |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 629 QDLCRQHMATKSLFNRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 688
|
| Bos taurus |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 629 QDLCRQHMATKSLFNRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 688
|
| Pongo pygmaeus |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 629 QDLCRQHMATKSLFNRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 688
|
| synthetic construct |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 241 QDLCRQHMATKSLFNRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 300
|
| Rattus sp. |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||||||||||||| # |||||||||||
Sbjct 572 QDLCRQHMATKSLFNRAEGQPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 631
|
| Canis familiaris |
Query 572 QDLCRQHMATKSLFNRAEGXXXXXXXXXXX#XXXXXXXXXXXXXXXXXXXWCEEPAQANMD 631
||||||||| ||||+|||| # |||||||||||
Sbjct 726 QDLCRQHMAAKSLFSRAEGPPEPSRVSSVS#SQFSDAAQASPSSHSSTPSWCEEPAQANMD 785
|
* References
[PubMed ID: 7887886] Kambayashi Y, Takahashi K, Bardhan S, Inagami T, Cloning and expression of protein tyrosine phosphatase-like protein derived from a rat pheochromocytoma cell line. Biochem J. 1995 Mar 1;306 ( Pt 2):331-5.
