logo CaMPDB: Calpain for Modulatory Proteolysis Database

XSB2997 : aplysia ras-related homolog A2 [Rattus norvegicus]

[ CaMP Format ]

This entry is computationally expanded from SB0038

* Basic Information

OrganismRattus norvegicus (Norway rat)
Protein NamesTransforming protein RhoA; aplysia ras-related homolog A2; plysia ras-related homolog A2
Gene NamesRhoa; Arha, Arha2; Arha; Arha2; ras homolog gene family, member A
Gene Locus16q12.5; chromosome 16
GO FunctionNot available
Entrez Protein Entrez Nucleotide Entrez Gene UniProt OMIM HGNC HPRD KEGG
NP_476473 NM_057132 117273 RHOA_RAT N/A N/A N/A rno:117273

* Information From OMIM

Not Available.

* Structure Information

1. Primary Information

Length: 193 aa

Average Mass: 21.782 kDa

Monoisotopic Mass: 21.768 kDa

2. Domain Information

Annotated Domains: interpro / pfam / smart / prosite

Computationally Assigned Domains (Pfam+HMMER):

domain namebeginendscoree-value
Ras 1. 7180336.45.6e-98
--- cleavage 180 (inside Ras 7..180) ---

3. Sequence Information

Fasta Sequence: XSB2997.fasta

Amino Acid Sequence and Secondary Structures (PsiPred):

4. 3D Information

Not Available.

* Cleavage Information

1 [sites]

Cleavage sites (±10aa)

[Site 1] FEMATRAALQ180-ARRGKKKSGC

Gln180 Ala

P10 P9 P8 P7 P6 P5 P4 P3 P2 P1
Phe171Glu172Met173Ala174Thr175Arg176Ala177Ala178Leu179Gln180
P1' P2' P3' P4' P5' P6' P7' P8' P9' P10'
Ala181Arg182Arg183Gly184Lys185Lys186Lys187Ser188Gly189Cys190

Sequence conservation (by blast)

* References

[PubMed ID: 19289122] Chevallier J, Koop C, Srivastava A, Petrie RJ, Lamarche-Vane N, Presley JF, Rab35 regulates neurite outgrowth and cell shape. FEBS Lett. 2009 Apr 2;583(7):1096-101. Epub 2009 Mar 14.

» More (9)